Patents by Inventor Leonard S. Jacob

Leonard S. Jacob has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-aqueous colonic purgative formulations
    Patent number: 6162464
    Abstract: Orally administered colonic purgative formulations and methods of its use for effecting partial or complete purgation of the colon in mammals, the formulations consisting of non-aqueous admixtures of a purgative salt selected from the group consisting of Mg.sub.3 (PO.sub.4).sub.2, MgHPO.sub.4, Mg(H.sub.2 PO.sub.4).sub.2, MgSO.sub.4, MgCl.sub.2, Na.sub.2 SO.sub.4, sodium tartrate, potassium tartrate, magnesium tartrate and mixtures, thereof, administered in tablet or capsule form in purgative effective concentrations. Preferred embodiments make use of at least one or more magnesium phosphate salts, more preferably dibasic magnesium phosphate; other preferred embodiments include the addition of binders, dispersants and buffers which do not adversely affect osmolality or effectiveness of the purgative formulations.
    Type: Grant
    Filed: March 31, 1997
    Date of Patent: December 19, 2000
    Assignee: Inkine Pharmaceutical, Inc.
    Inventors: Leonard S. Jacob, Taffy J. Williams, Robert D. Krell
  • Treatment of gynecological malignancies with biologically active peptides
    Patent number: 5635479
    Abstract: A process for treating a gynecological malignancy in a host which comprises administering to the host at least one biologically active amphiphilic peptide or protein. The peptide or protein may be administered intralesionally, intravenously, or intraperitoneally, whereby the peptide or protein may inhibit, prevent, or destroy the growth of the gynecological malignancy, such as an ovarian cancer, uterine cancer, or cervical cancer.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: June 3, 1997
    Assignee: Magainin Pharmaceuticals Inc.
    Inventors: Leonard S. Jacob, W. Lee Maloy, Margaret A. Baker
  • Wound treatment employing biologically active ion channel forming peptides and proteins
    Patent number: 5045531
    Abstract: A process for treating a wound in a host which comprises administering to the host having a wound at least one biologically active amphiphilic peptide. The peptide is an ion channel-forming peptide and is administered in an amount effective for treating a wound in a host.
    Type: Grant
    Filed: December 18, 1989
    Date of Patent: September 3, 1991
    Assignee: Magainin Sciences Inc.
    Inventors: Barry Berkowitz, Leonard S. Jacob
  • Wound treatment employing biologically active ion channel forming peptides and proteins
    Patent number: RE35492
    Abstract: A process for treating a wound in a host which comprises administering to the host having a wound at least one biologically active amphiphilic peptide. The peptide is an ion channel-forming peptide and is administered in an amount effective for treating a wound in a host.
    Type: Grant
    Filed: September 8, 1994
    Date of Patent: April 8, 1997
    Assignee: Magainin Pharmaceuticals, Inc.
    Inventors: Barry Berkowitz, Leonard S. Jacob