Patents by Inventor Leonard W. Mayer

Leonard W. Mayer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective detection of
    Patent number: 10683558
    Abstract: A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: June 16, 2020
    Assignee: THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETRARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Jennifer Thomas, Xin Wang, Cynthia Hatcher, Raydel Anderson, Mary Jordan Theodore, Leonard W. Mayer
  • Selective detection of
    Patent number: 10669591
    Abstract: A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: June 2, 2020
    Assignee: THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Jennifer Thomas, Xin Wang, Cynthia Hatcher, Raydel Anderson, Mary Jordan Theodore, Leonard W. Mayer
  • SELECTIVE DETECTION OF HAEMOPHILUS INFLUENZAE
    Publication number: 20170145479
    Abstract: A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 25, 2017
    Inventors: Jennifer Thomas, Xin Wang, Cynthia Hatcher, Raydel Mair, Mary Jordan Theodore, Leonard W. Mayer
  • SELECTIVE DETECTION OF HAEMOPHILUS INFLUENZAE
    Publication number: 20170145480
    Abstract: A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 25, 2017
    Inventors: Jennifer Thomas, Xin Wang, Cynthia Hatcher, Raydel Mair, Mary Jordan Theodore, Leonard W. Mayer
  • Selective detection of
    Patent number: 9593385
    Abstract: A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: March 14, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Jennifer Dolan Thomas, Xin Wang, Cynthia Hatcher, Raydel Anderson, Mary Jordan Theodore, Leonard W. Mayer
  • SELECTIVE DETECTION OF HAEMOPHILUS INFLUENZAE
    Publication number: 20130295557
    Abstract: A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
    Type: Application
    Filed: January 26, 2012
    Publication date: November 7, 2013
    Applicant: Centers for Disease Control and Prevention
    Inventors: Jennifer Dolan Thomas, Xin Wang, Cynthia Hatcher, Raydel Anderson, Mary Jordan Theodore, Leonard W. Mayer
  • Nucleic acids of the M antigen gene of , antigens, vaccines and antibodies, methods and kits for detecting histoplasmas
    Patent number: 7018827
    Abstract: The present invention provides the nucleotide sequence of the M antigen gene of H. capsulatum, which is set forth in the Sequence Listing as SEQ ID NO:1, a nucleic acid having the nucleotide sequence complementary thereto, and nucleic acids having a nucleotide sequence which is substantially the same as the foregoing nucleotide sequences. The present invention also provides vectors and host expressions systems containing the foregoing nucleic acids, and isolated or recombinantly-produced antigens encoded by the foregoing nucleic acids. The present invention further provides antibodies generated against the foregoing antigens, and methods and kits for detecting a previous or current Histoplasma capsulatum infection in a subject, and for diagnosing histoplasmosis.
    Type: Grant
    Filed: April 27, 1999
    Date of Patent: March 28, 2006
    Assignees: The United States of America as represented by the Department of Health and Human Services, University of Cincinnati
    Inventors: Rosely M. Zancope-Oliveira, Timothy J. Lott, Leonard W. Mayer, Errol Reiss, George S. Deepe