Patents by Inventor Leonardo Puerta Llerena

Leonardo Puerta Llerena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion proteins representing different allergens and a vaccine against allergy to mites
    Patent number: 9163069
    Abstract: The present invention refers to recombinant DNA molecules encoding fusion peptides from different allergens from Blomia tropicalis and Dermatophagoides pteronyssinus having potential usefulness in prevention and treatment of allergies caused by domestic mites. Specifically, the invention discloses fusion proteins comprising different fragments of allergens Der p 1, Der p 2, Der p 7, Der p 8, Blo t 5, Blo t 8, Blo t 18, Blo t 12 and Blo t 13 with reduced serum IgE reactivity in allergic and non-allergic individuals. It also discloses methods for production of these molecules in an expression system based on E. coli and purification. The invention refers also to effective and safe vaccines.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: October 20, 2015
    Assignee: UNIVERSIDAD DE CARTAGENA
    Inventors: Leonardo Puerta Llerena, Luis Caraballo, José Fernando Cantillo