Patents by Inventor Leonardo R. Allain

Leonardo R. Allain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATING ACUTE MIGRAINE WITH CGRP-ACTIVE COMPOUND
    Publication number: 20230248715
    Abstract: A method of alleviating or mitigating at least one symptom of migraine attack by administering to a patient suffering from a migraine attack a therapeutically effective amount of the compound of Formula I: or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 21, 2023
    Publication date: August 10, 2023
    Inventors: Chi-Chung Liu, David Michelson, Gene Marcantonio, Kyle Fliszer, Rebecca White, Mark E. Fraley, Leonardo R. Allain, Tiffani Voss, John Limanto
  • FORMULATIONS FOR CGRP RECEPTOR ANTAGONISTS
    Publication number: 20210330660
    Abstract: The instant invention relates to liquid pharmaceutical compositions containing CGRP receptor antagonists. The CGRP receptor antagonist liquid pharmaceutical compositions of the instant invention are alcohol-free, low volume liquid pharmaceutical compositions that can be taken without water for the treatment of migraine headache.
    Type: Application
    Filed: December 7, 2020
    Publication date: October 28, 2021
    Inventors: Majid Mahjour, Leonardo R. Allain, Sutthilug Sotthivirat, Russell G. Maus, Rebecca Nofsinger, Lisa Lupton, Wei Xu, Francis Flanagan
  • Pharmaceutical compositions containing doravirine, tenofovir disoproxil fumarate and lamivudine
    Patent number: 10842751
    Abstract: The instant invention relates to pharmaceutical compositions comprising doravirine, tenofovir disoproxil fumarate and lamivudine. These compositions are useful for the treatment of HIV infection. Also disclosed are processes for making said pharmaceutical compositions.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: November 24, 2020
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: Santipharp Panmai, Aditya Tatavarti, Andrew M. Farrington, Varsha Biyyala, Leonardo R. Allain, Marcela Nefliu, Gerard R. Klinzing, Jie Ren, Matthew Lamm
  • PHARMACEUTICAL COMPOSITIONS CONTAINING DORAVIRINE, TENOFOVIR DISOPROXIL FUMARATE AND LAMIVUDINE
    Publication number: 20200179291
    Abstract: The instant invention relates to pharmaceutical compositions comprising doravirine, tenofovir disoproxil fumarate and lamivudine. These compositions are useful for the treatment of HIV infection. Also disclosed are processes for making said pharmaceutical compositions.
    Type: Application
    Filed: February 14, 2020
    Publication date: June 11, 2020
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Santipharp Panmai, Aditya Tatavarti, Andrew M. Farrington, Varsha Biyyala, Leonardo R. Allain, Marcela Nefliu, Gerard R. Klinzing, Jie Ren, Matthew Lamm
  • Pharmaceutical compositions containing doravirine, tenofovir disoproxil fumarate and lamivudine
    Patent number: 10603282
    Abstract: The instant invention relates to pharmaceutical compositions comprising doravirine, tenofovir disoproxil fumarate and lamivudine. These compositions are useful for the treatment of HIV infection. Also disclosed are processes for making said pharmaceutical compositions.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: March 31, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Santipharp Panmai, Aditya Tatavarti, Andrew M. Farrington, Varsha Biyyala, Leonardo R. Allain, Marcela Nefliu, Gerard R. Klinzing, Jie Ren, Matthew Lamm
  • PHARMACEUTICAL COMPOSITIONS CONTAINING DORAVIRINE, TENOFOVIR DISOPROXIL FUMARATE AND LAMIVUDINE
    Publication number: 20190254977
    Abstract: The instant invention relates to pharmaceutical compositions comprising doravirine, tenofovir disoproxil fumarate and lamivudine. These compositions are useful for the treatment of HIV infection. Also disclosed are processes for making said pharmaceutical compositions.
    Type: Application
    Filed: November 29, 2016
    Publication date: August 22, 2019
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Santipharp Panmai, Aditya Tatavarti, Andrew M. Farrington, Varsha Biyyala, Leonardo R. Allain, Marcela Nefliu, Gerard R. Klinzing, Jie Ren, Matthew Lamm
  • FORMULATIONS FOR CGRP RECEPTOR ANTAGONISTS
    Publication number: 20190070161
    Abstract: The instant invention relates to liquid pharmaceutical compositions containing CGRP receptor antagonists. The CGRP receptor antagonist liquid pharmaceutical compositions of the instant invention are alcohol-free, low volume liquid pharmaceutical compositions that can be taken without water for the treatment of migraine headache.
    Type: Application
    Filed: September 10, 2018
    Publication date: March 7, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Majid Mahjour, Leonardo R. Allain, Sutthilug Sotthivirat, Russell G. Maus, Rebecca Nofsinger, Lisa Lupton, Wei Xu, Francis Flanagan
  • FORMULATIONS FOR CGRP RECEPTOR ANTAGONISTS
    Publication number: 20160220552
    Abstract: The instant invention relates to liquid pharmaceutical compositions containing CGRP receptor antagonists. The CGRP receptor antagonist liquid pharmaceutical compositions of the instant invention are alcohol-free, low volume liquid pharmaceutical compositions that can be taken without water for the treatment of migraine headache.
    Type: Application
    Filed: September 11, 2014
    Publication date: August 4, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Majid Mahjour, Leonardo R. Allain, Sutthilug Sotthivirat, Russell G. Maus, Rebecca Nofsinger, Lisa Lupton, Wei Xu, Francis Flanagan
  • METHOD FOR DETERMINING COMPATIBILITY OF AN ACTIVE PHARMACEUTICAL INGREDIENT WITH MATERIALS
    Publication number: 20100216667
    Abstract: Disclosed is a system or matrix approach for determining compatibility of a pharmaceutically active substance, such as small molecule drug candidate, therapeutic proteins, peptides, vaccines or RNAi, with materials used in the research and development of pharmaceuticals, including plastics, polymers, resins, rubbers, elastomers, glass and steel.
    Type: Application
    Filed: December 17, 2009
    Publication date: August 26, 2010
    Inventors: Brian K. Meyer, Leonardo R. Allain, David Geer, Rajiv Mahajan, David R. Walker, Marc J. Kirchmeier