Patents by Inventor Leonardo Rabaglia

Leonardo Rabaglia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Taste Masked Oral Composition of Telithromycin
    Publication number: 20110020442
    Abstract: The invention relates to an oral compositions comprising telithromycin that have taste masking properties, a process for the preparation thereof, and methods of using the composition.
    Type: Application
    Filed: October 7, 2010
    Publication date: January 27, 2011
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Philippe Becourt, Nicoletta Cioloca, Luigi Boltri, Stefano De Luigi Bruschi, Luigi Giovanni Mapelli, Leonardo Rabaglia, Detlev Schwabe
  • Drug activation process and vibrational mill therefor
    Patent number: 7793871
    Abstract: The invention comprises a process for activating drugs by means of high-energy co-grinding of the drug with a pharmaceutical carrier, characterized by the use of a vibrational mill equipped with means that regulate the vibration frequency. The process, performed by modifying the frequency of vibration and keeping its amplitude constant, produces drug/carrier composites with a constant particle size in which the degree of drug activation increases in proportion to the frequency applied. The invention also includes a vibrational mill suitably modified to perform the process described.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: September 14, 2010
    Assignee: Eurand Pharmaceuticals Ltd.
    Inventors: Luca Dobetti, Leonardo Rabaglia, Massimo Bresciani
  • DRUG ACTIVATION PROCESS AND VIBRATIONAL MILL THEREFOR
    Publication number: 20080251615
    Abstract: The invention comprises a process for activating drugs by means of high-energy co-grinding of the drug with a pharmaceutical carrier, characterised by the use of a vibrational mill equipped with means that regulate the vibration frequency. The process, performed by modifying the frequency of vibration and keeping its amplitude constant, produces drug/carrier composites with a constant particle size in which the degree of drug activation increases in proportion to the frequency applied. The invention also includes a vibrational mill suitably modified to perform the process described.
    Type: Application
    Filed: June 25, 2008
    Publication date: October 16, 2008
    Applicant: EURAND PHARMACEUTICALS LTD.
    Inventors: Luca Dobetti, Leonardo Rabaglia, Massimo Bresciani
  • Process for the preparation of pharmaceutical microcapsules with enhanced taste-masking and high dissolution rate
    Publication number: 20050269722
    Abstract: Process for the production of microcapsules containing a drug and comprising a layer of ethylcellulose and a layer of an acrylic polymer and microcapsules produced thereby.
    Type: Application
    Filed: July 17, 2002
    Publication date: December 8, 2005
    Inventors: Stefano De Luigi Brushci, Luigi Mapelli, Leonardo Rabaglia, Luigi Boltri
  • Drug activation process and vibrational mill therefor
    Publication number: 20040166155
    Abstract: The invention comprises a process for activating drugs by means of high-energy co-grinding of the drug with a pharmaceutical carrier, characterised by the use of a vibrational mill equipped with means that regulate the vibration frequency. The process, performed by modifying the frequency of vibration and keeping its amplitude constant, produces drug/carrier composites with a constant particle size in which the degree of drug activation increases in proportion to the frequency applied. The invention also includes a vibrational mill suitably modified to perform the process described.
    Type: Application
    Filed: December 18, 2003
    Publication date: August 26, 2004
    Inventors: Luca Dobetti, Leonardo Rabaglia, Massimo Bresciani
  • Taste masked oral composition of telithromycin
    Publication number: 20040013737
    Abstract: The invention relates to an oral compositions comprising telithromycin that have taste masking properties, a process for the preparation thereof, and methods of using the compsition.
    Type: Application
    Filed: July 19, 2002
    Publication date: January 22, 2004
    Inventors: Philippe Becourt, Nicoletta Cioloca, Luigi Boltri, Stefano De Luigi Bruschi, Luigi Giovanni Mapelli, Leonardo Rabaglia, Detlev Schwabe
  • Therapeutic compositions with controlled release of medicaments supported on crosslinked polymers and coated with polymer films, and their preparation process
    Patent number: 5275824
    Abstract: The described therapeutic compositions with controlled release of medicaments comprise a medicament loaded onto particles of a crosslinked non-ionic polymer insoluble but swellable in water, using either swelling with solutions of the medicament or high-energy co-grinding methods. The medicament-loaded particles are coated with a polymers film able to control medicament release, to obtain a prolonged release of the medicament (even exceeding 24 hours) while maintaining high bioavailability.
    Type: Grant
    Filed: December 3, 1990
    Date of Patent: January 4, 1994
    Assignee: Vectorpharma International spa
    Inventors: Fabio Carli, Italo Colombo, Leonardo Rabaglia