Patents by Inventor Leonardo Ruiz Esquvel

Leonardo Ruiz Esquvel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pulsed field gel electrophoresis chambers, accessories and methods of use for the separation of DNA molecules
    Patent number: 8034225
    Abstract: Methods of use, accessories and chambers, optimal for performing Pulsed Field Gel Electrophoresis (PFGE) of DNA molecules in ‘Contour Clamped Homogeneous Electric Field’ (CHEF) and ‘Transversal Alternating Field Electrophoresis’ (TAFE) systems, are provided herein. DNA molecules are rapidly separated in the minigels of these chambers. The sizes of chambers and accessories are determined by the separation between the opposite polarity electrodes; which is comprised between 6.2 and 15 cm. Reproducibility of molecule separation is achieved because the accessories warrant homogeneous electric resistance in the buffer and minigels. Chambers allow a high-throughput sample format using the reagents efficiently. It is attained excluding the non-useful electrophoresis zones. For a better optimization, TAFE chambers have several useful electrophoresis zones (UEZ), each carrying a minigel.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: October 11, 2011
    Assignee: Centro Nacional de Investigaciones Cientificas
    Inventors: Ana Maria Riveron Rojas, Lilia Lopez Canovas, Oscar Arencibia Diaz, Jose Alfredo Herrera Isidron, Gabriel Perez Perez, Esther Orozco Orozco, Carlos Alberto Canino Ramos, Luis Mariano Batista Santiler, Regnar Gigato Perez, Leonardos Ruiz Esquvel, Maria Dolores Noa Blanco, Elisa Javert Higginson
  • Pulsed Field Gel Electrophoresis chambers, accessories and methods of use for the separation of DNA molecules
    Publication number: 20070102298
    Abstract: Methods of use, accessories and chambers, optimal for performing Pulsed Field Gel Electrophoresis (PFGE) of DNA molecules in ‘Contour Clamped Homogeneous Electric Field’ (CHEF) and ‘Transversal Alternating Field Electrophoresis’ (TAFE) systems, are provided herein. DNA molecules are rapidly separated in the minigels of these chambers. The sizes of chambers and accessories are determined by the separation between the opposite polarity electrodes; which is comprised between 6.2 and 15 cm. Reproducibility of molecule separation is achieved because the accessories warrant homogeneous electric resistance in the buffer and minigels. Chambers allow a high-throughput sample format using the reagents efficiently. It is attained excluding the non-useful electrophoresis zones. For a better optimization, TAFE chambers have several useful electrophoresis zones (UEZ), each carrying a minigel.
    Type: Application
    Filed: December 21, 2006
    Publication date: May 10, 2007
    Inventors: Ana Riveron Rojas, Lilia Lopez Canovas, Oscar Arencibia Diaz, Jose Herrera Isidron, Gabriel Perez Perez, Esther Orozco Orozco, Carlos Canino Ramos, Luis Batista Santiler, Regnar Gigato Perez, Leonardo Ruiz Esquvel, Maria Noa Blanco, Elisa Javert Higginson