Patents by Inventor Leonardo S. SANTOS

Leonardo S. SANTOS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PAMAM, spacer molecule and cafestol polymers
    Patent number: 9198973
    Abstract: The present invention is directed to a polymeric compound with a size in a nanometric scale, useful as a biocompatible carrier for the transport and delivery of active agents into a fish, insect, animal, reptile, bird, human, or plant, wherein said polymeric compound comprises PAMAM (polyamidoamine) dendrimers, a spacer molecule, and cafestol, wherein the polymeric compound of the invention comprises a structure of the kind (cafestol-PAMAM derivative)2-spacer molecule. Use of the compound as a biocompatible carrier for transport and delivery of antithrombotic active agents is disclosed. Procedures for obtaining a polymeric compound comprising the activation of cafestol, activation of polyethylene glycol, and formation of cafestol-PAMAM-PEG-PAMAM-cafestol are also disclosed.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: December 1, 2015
    Assignees: Fundacion Fraunhofer Chile Research, Universidad de Talca
    Inventors: Leonardo S. Santos, John Amalraj, Esteban F. Duran Lara, Fabiane M. Nachtigall
  • PAMAM, SPACER MOLECULE AND CAFESTOL POLYMERS
    Publication number: 20140371401
    Abstract: The present invention is directed to a polymeric compound with a size in a nanometric scale, useful as a biocompatible carrier for the transport and delivery of active agents into a fish, insect, animal, reptile, bird, human, or plant, wherein said polymeric compound comprises PAMAM (polyamidoamine) dendrimers, a spacer molecule, and cafestol, wherein the polymeric compound of the invention comprises a structure of the kind (cafestol-PAMAM derivative)2-spacer molecule. Use of the compound as a biocompatible carrier for transport and delivery of antithrombotic active agents is disclosed. Procedures for obtaining a polymeric compound comprising the activation of cafestol, activation of polyethylene glycol, and formation of cafestol-PAMAM-PEG-PAMAM-cafestol are also disclosed.
    Type: Application
    Filed: June 17, 2013
    Publication date: December 18, 2014
    Inventors: Leonardo S. SANTOS, John AMALRAJ, Esteban F. DURAN LARA, Fabiane M. NACHTIGALL