Patents by Inventor Leonardus Wendelinus Mathias Marie Terstappen

Leonardus Wendelinus Mathias Marie Terstappen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200191793
    Abstract: Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like. Test kits that facilitate the detection, enumeration and analysis of such circulating tumor cells are also provided.
    Type: Application
    Filed: July 8, 2019
    Publication date: June 18, 2020
    Applicants: Janssen Diagnostics, LLC, Pfizer Inc.
    Inventors: Antonio GUALBERTO, Maria Luisa PACCAGNELLA, Carrie L. MELVIN, Madeline I. REPOLLET, David CHIANESE, Mark Carle CONNELLY, Leonardus Wendelinus Mathias Marie TERSTAPPEN
  • Patent number: 9975125
    Abstract: A micro well plate is described for capturing and distributing single cells in individual wells is described, wherein at least one individual well is provided with a bottom plate having at least one pore to pass sample liquid, such that if one object or cell of interest is collected on the bottom plate of the well, the sample flow rate through that particular well is significantly reduced, minimizing the possibility that multiple cells or objects of interest entering the same well. The presented invention is particularly suited for obtaining single cells and/or microorganisms suspended in fluid samples for subsequent detailed interrogation.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: May 22, 2018
    Assignee: VyCAP, B.V.
    Inventors: Arjan Gerhardus Johannes Tibbe, Cornelis Johannes Maria van Rijn, Leonardus Wendelinus Mathias Marie Terstappen
  • Publication number: 20180011103
    Abstract: Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like. Test kits that facilitate the detection, enumeration and analysis of such circulating tumor cells are also provided.
    Type: Application
    Filed: July 27, 2017
    Publication date: January 11, 2018
    Applicants: Janssen Diagnostics, LLC, Pfizer Inc.
    Inventors: Antonio GUALBERTO, Maria Luisa PACCAGNELLA, Carrie L. MELVIN, Madeline I. REPOLLET, David CHIANESE, Mark Carle CONNELLY, Leonardus Wendelinus Mathias Marie TERSTAPPEN
  • Publication number: 20170189907
    Abstract: A micro well plate is described for capturing and distributing single cells in individual wells is described, wherein at least one individual well is provided with a bottom plate having at least one pore to pass sample liquid, such that if one object or cell of interest is collected on the bottom plate of the well, the sample flow rate through that particular well is significantly reduced, minimizing the possibility that multiple cells or objects of interest entering the same well. The presented invention is particularly suited for obtaining single cells and/or microorganisms suspended in fluid samples for subsequent detailed interrogation.
    Type: Application
    Filed: March 21, 2017
    Publication date: July 6, 2017
    Applicant: VyCAP B.V.
    Inventors: Arjan Gerhardus Johannes Tibbe, Cornelis Johannes Maria van Rijn, Leonardus Wendelinus Mathias Marie Terstappen
  • Patent number: 9638636
    Abstract: A micro well plate is described for capturing and distributing single cells in individual wells is described, wherein at least one individual well is provided with a bottom plate having at least one pore to pass sample liquid, such that if one object or cell of interest is collected on the bottom plate of the well, the sample flow rate through that particular well is significantly reduced, minimizing the possibility that multiple cells or objects of interest entering the same well. The presented invention is particularly suited for obtaining single cells and/or microorganisms suspended in fluid samples for subsequent detailed interrogation.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: May 2, 2017
    Assignee: VyCAP B.V.
    Inventors: Arjan Gerhardus Johannes Tibbe, Cornelis Johannes Maria van Rijn, Leonardus Wendelinus Mathias Marie Terstappen
  • Publication number: 20150177252
    Abstract: Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like. Test kits that facilitate the detection, enumeration and analysis of such circulating tumor cells are also provided.
    Type: Application
    Filed: December 22, 2014
    Publication date: June 25, 2015
    Inventors: Antonio Gualberto, Maria Luisa Paccagnella, Carrie L. Melvin, Madeline I. Repollet, David Chianese, Mark Carle Connelly, Leonardus Wendelinus Mathias Marie Terstappen
  • Publication number: 20150160135
    Abstract: A micro well plate is described for capturing and distributing single cells in individual wells is described, wherein at least one individual well is provided with a bottom plate having at least one pore to pass sample liquid, such that if one object or cell of interest is collected on the bottom plate of the well, the sample flow rate through that particular well is significantly reduced, minimizing the possibility that multiple cells or objects of interest entering the same well. The presented invention is particularly suited for obtaining single cells and/or microorganisms suspended in fluid samples for subsequent detailed interrogation.
    Type: Application
    Filed: May 5, 2013
    Publication date: June 11, 2015
    Applicant: VyCAP B.V.
    Inventors: Arjan Gerhardus Johannes Tibbe, Cornelis Johannes Maria van Rijn, Leonardus Wendelinus Mathias Marie Terstappen
  • Patent number: 8940493
    Abstract: Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like. Test kits that facilitate the detection, enumeration and analysis of such circulating tumor cells are also provided.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: January 27, 2015
    Assignees: Veridex LLC, Pfizer Inc.
    Inventors: Antonio Gualberto, Maria Luisa Paccagnella, Carrie L. Melvin, Madeline I. Repollet, David Chianese, Mark Carle Connelly, Leonardus Wendelinus Mathias Marie Terstappen
  • Publication number: 20100028915
    Abstract: Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like. Test kits that facilitate the detection, enumeration and analysis of such circulating tumor cells are also provided.
    Type: Application
    Filed: May 29, 2007
    Publication date: February 4, 2010
    Inventors: Antonio Gualberto, Maria Luisa Paccagnella, Carrie L. Melvin, Madeline I. Repollet, David Chianese, Mark Carle Connelly, Leonardus Wendelinus Mathias Marie Terstappen