Patents by Inventor Leone Bertone

Leone Bertone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ethers of substituted hydroxymethlypyrazines
    Patent number: 4801711
    Abstract: Alkoxy methyl pyrazine N-oxides having anti lypolytic, hypotriglyceridemic and hypocholesterolaemic properties and utility are disclosed.
    Type: Grant
    Filed: June 16, 1987
    Date of Patent: January 31, 1989
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Paolo Cozzi, Antonio Pillan, Leone Bertone, Pier P. Lovisolo
  • Ethers of substituted hydroxymethylpyrazines
    Patent number: 4766214
    Abstract: The compounds of the invention have the following general formula (I) ##STR1## wherein each of the groups R, R.sub.1 and R.sub.2, which may be the same or different, represents a hydrogen atom, a C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.6 alkyl group, and R.sub.3 represents a straight or branched chain, saturated or unsaturated, C.sub.1 -C.sub.8 aliphatic hydrocarbon group. The compounds are useful as antilipolytic agents.
    Type: Grant
    Filed: December 5, 1986
    Date of Patent: August 23, 1988
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Leone Bertone, Pier P. Lovisolo
  • Ethers of substituted hydroxymethylpyrazines
    Patent number: 4406901
    Abstract: Ethers of substituted hydroxymethylpyrazines, such as, for instance, the compound 2-methoxymethyl-5-methylpyrazine-4-oxide. The compounds exhibit elevated lipid-lowering activity, especially anti-lipolytic activity (decrease of plasma-free fatty acids), triglyceride-lowering activity, cholesterol-lowering activity, and plasma-phospholipid-lowering activity.
    Type: Grant
    Filed: November 16, 1981
    Date of Patent: September 27, 1983
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Leone Bertone, Pier P. Lovisolo
  • 2-Hydroxymethyl-pyrazine derivatives and process for their preparation
    Patent number: 4267327
    Abstract: 2-Hydroxymethyl-pyrazine derivatives are disclosed, such as, for instance, the compound 2-hydroxymethyl-5-methylpyrazine-4-oxide. The compounds exhibit an elevated lipid lowering activity, and can be used to control triglyceride and cholesterol levels.
    Type: Grant
    Filed: February 26, 1979
    Date of Patent: May 12, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Osvaldo Magni, Leone Bertone, Romano Angelucci, Pier P. Lovisolo