Patents by Inventor Leonhard Hafner

Leonhard Hafner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the purification of insulins by chromatography
    Patent number: 5245008
    Abstract: A process for the purification of insulins and insulin derivatives by chromatography in aqueous, buffered solvents which contain water-miscible organic solvents, on lipophilically modified silica gel, is described, wherein the aqueous, buffered solvents contain zwitterions, or the pH of the solvent mixture is in the vicinity of the isoelectric point of the insulin or insulin derivative to be purified and zwitterions are present.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: September 14, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rainer Dickhardt, Bernhard Unger, Leonhard Hafner
  • Process for the simultaneous obtention of insulin and pancreatin from swine pancreases
    Patent number: 4029641
    Abstract: A process for the simultaneous obtention of insulin and pancreatin from fresh or deep frozen swine pancreases by extracting the glands at a pH of about 5 to 7 with a reaction mixture containing at least 40% of acetone, separating the extracted substance and the remaining solids, instantly adjusting the solids to a pH of above 5.6 with a buffer, and then recovering insulin from the extraction mixture and pancreatin from the solids.
    Type: Grant
    Filed: December 18, 1975
    Date of Patent: June 14, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Leonhard Hafner, Wilhelm Schramm, Hans Kargl, Friedrich Kieser