Abstract: Devices of this invention include replaceable cartridges for delivery of doses of fluids. Cartridges having a fluid supply reservoir comprising an expandable element are designed to be connected with non-disposable actuating module supplied with a sensor, a mechanism to apply a force to the fluid, thereby forcing a predetermined dose out of the reservoir, and a processor providing control outputs from a sensor system according to preprogrammed instructions. Methods of this invention include delivery of microdoses of fluids using devices of this invention.

Abstract: Methods and compact automatic devices are provided for delivery of micro doses of liquid drugs to a patient. Devices have a fluid supply reservoir comprising an expandable indicator supplied with a sensor, a mechanism forcing the fluid to squeeze predetermined dose out, and a processor treating sensor's signals accordingly to preprogrammed algorithm. The method comprises steps: (a) initiating the delivery cycle, (b) acquiring sensor's signals, (c) treating signals in order to integrate an intensity of output flow and to determine when the squeezing-out force must be terminated, (d) terminating the cycle accordingly to processor's command. Self-testing of devices occurs while each fluid delivery cycle. Their high dosing precision exceeds that of known analogs about two orders of magnitude. A possibility to use low cost disposable exit port assembly and/or easy replaceable factory pre-filled cartridges is an additional advantage eliminating risks of overdosing, air bubbles, and/or compromised sterility.

Abstract: Devices of this invention include replaceable cartridges for delivery of doses of fluids. Cartridges having a fluid supply reservoir comprising an expandable element are designed to be connected with non-disposable actuating module supplied with a sensor, a mechanism to apply a force to the fluid, thereby forcing a predetermined dose out of the reservoir, and a processor providing control outputs from a sensor system according to preprogrammed instructions. Methods of this invention include delivery of microdoses of fluids using devices of this invention.

Abstract: Methods and compact automatic devices are provided for delivery of micro doses of liquid drugs to a patient. Devices have a fluid supply reservoir comprising an expandable indicator supplied with a sensor, a mechanism forcing the fluid to squeeze predetermined dose out, and a processor treating sensor's signals accordingly to preprogrammed algorithm. The method comprises steps: (a) initiating the delivery cycle, (b) acquiring sensor's signals, (c) treating signals in order to integrate an intensity of output flow and to determine when the squeezing-out force must be terminated, (d) terminating the cycle accordingly to processor's command. Self-testing of devices occurs while each fluid delivery cycle. Their high dosing precision exceeds that of known analogs about two orders of magnitude. A possibility to use low cost disposable exit port assembly and/or easy replaceable factory pre-filled cartridges is an additional advantage eliminating risks of overdosing, air bubbles, and/or compromised sterility.

Abstract: Quantum nanowires are produced in a medium comprising ions, dopants and free electrons, wherein the free electrons are solvated by complexes of ions and dopants. Electrical conductivity of the quantum nanowires can be higher than for conventional metal conductors. Quantum nanowires can be prepared in linear or circular form, and can be used to manufacture electrical components including transistors, sensors, motors and other nanoscale passive or active devices. Nanoscale devices can be made in liquid, semisolid, or solid media. Methods are provided for the manufacture of quantum nanowires and devices made therefrom. The devices can be used in the manufacture of computers, electronic circuits, biological implants and other products.

Abstract: A polymer material comprising channels whose temperature-independent conductivity exceeds 106 S/cm is used to form conductive films. Conduction takes place through threads and channels passing through the film which is otherwise a dielectric. The film is produced by first depositing a macromolecular polymer substance on a substrate. During preparation, the substance is preferably in a viscous liquid state. Stable free electrons (polarons) are then created by ionizing the substance. This is assisted by exposure to UV radiation and the presence of strong polar groups in the polymer. Various enrichment techniques, such as applying a strong electric field, are then used to join the superpolarons together into conductive threads within the medium. To stabilize the positions of the threads, the medium then may be solidified, preferably by cooling it below its glass transition point or inducing cross-linking between the macromolecules. The film may be a membrane.