Patents by Inventor Leonid Iakoubov

Leonid Iakoubov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of nucleic acids to assess risk for bovine spongiform encephalopathy
    Patent number: 7368243
    Abstract: The present invention provides a method of detecting abnormal serum nucleic acid profiles to assess the risk of a transmissible spongiform encephalopathy, e.g., BSE.
    Type: Grant
    Filed: July 8, 2005
    Date of Patent: May 6, 2008
    Assignee: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Leonid Iakoubov, Howard Urnovitz
  • Detection of nucleic acids to assess risk for Creutzfeldt-Jakob disease
    Publication number: 20060099621
    Abstract: The present invention provides a method of detecting abnormal circulating nucleic acid profiles to assess the risk of Creutzfeldt-Jakob Disease.
    Type: Application
    Filed: October 7, 2005
    Publication date: May 11, 2006
    Applicant: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Leonid Iakoubov, Howard Urnovitz
  • Detection of nucleic acids to assess risk for bovine spongiform encephalopathy
    Publication number: 20060068419
    Abstract: The present invention provides a method of detecting abnormal serum nucleic acid profiles to assess the risk of a transmissible spongiform encephalopathy, e.g., BSE.
    Type: Application
    Filed: July 8, 2005
    Publication date: March 30, 2006
    Applicant: Chronix Biomedical
    Inventors: Ekkehard Schuetz, Leonid Iakoubov, Howard Urnovitz
  • Methods for generating an mRNA expression profile from an ecellular mRNA containing blood sample and using the same to identify functional state markers
    Publication number: 20030036077
    Abstract: Methods for generating an mRNA expression profile are provided. In the subject methods, a population of nucleic acid targets is first generated from an acellular blood sample that contains a plurality of distinct mRNAs, i.e., a disease specific particular blood fraction. The resultant nucleic acid targets are hybridized to an array of nucleic acid probes to obtain an mRNA expression profile. The subject mRNA expression profiles are useful in the identification of disease specific markers. In such applications, the mRNA expression profiles are compared to a control expression profile to identify disease specific markers, where the identified markers subsequently find use in diagnostic applications. The subject methods also find use in diagnostic applications, where the mRNA expression profile is compared to a reference in making a diagnosis of the presence of a disease condition. Finally, kits for use in practicing the various methods are provided.
    Type: Application
    Filed: May 31, 2002
    Publication date: February 20, 2003
    Applicant: Chronix Biomedical
    Inventors: Alex Chenchik, Leonid Iakoubov, Howard B. Urnovitz