Patents by Inventor Leonid METELITSA

Leonid METELITSA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAR NKTs Expressing Artificial Micro RNA-Embedded shRNA for Downregulation of MHC Class I & II Expression
    Publication number: 20220348930
    Abstract: The present disclosure provides methods and compositions related to Natural Killer T cells that are engineered to knock down the expression of one or more endogenous major histocompatibility complex (MHC) gene. The present disclosure also provides engineered CAR NKT cells that resist rejection by allogeneic immune cells both in vitro and in vivo.
    Type: Application
    Filed: April 22, 2022
    Publication date: November 3, 2022
    Applicant: Baylor College of Medicine
    Inventors: Andras HECZEY, Bin LIU, Leonid METELITSA