Patents by Inventor Leonid Ptitsyn

Leonid Ptitsyn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING L-AMINO ACIDS USING BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY
    Publication number: 20070212764
    Abstract: There is disclosed a method for producing an L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan, or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of N-acetylglucosamine permease encoded by the nagE gene.
    Type: Application
    Filed: January 11, 2006
    Publication date: September 13, 2007
    Inventors: Leonid Ptitsyn, Irina Altman, Veronika Kotliarova, Yury Kozlov
  • Carbamoylphosphate synthetase and method for producing compounds derived from carbamoylphosphate
    Publication number: 20060035343
    Abstract: L-arginine, citrulline and pyrimidine derivatives including orotic acid, uridine, uridine 5?-monophosphate (UMP), cytidine and cytidine. 5?-monophosphate (CMP) are produced using a bacterium belonging to the genus Escherichia harboring a mutant carbamoylphosphate synthetase in which the amino acid sequence corresponding to positions from 947 to 951 in a wild type carbamoylphosphate synthetase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 9, and feedback inhibition by uridine 5?-monophosphate in the bacterium is desensitized.
    Type: Application
    Filed: October 20, 2005
    Publication date: February 16, 2006
    Applicant: AJINOMOTO CO., INC
    Inventors: Leonid Ptitsyn, Sergey Smirnov, Irina Altman, Anna Novikova, Veronika Kotliarova, Mikhail Gusyatiner, Yulia Rostova, Tatyana Yampolskaya
  • Method for producing L-threonine using bacteria belonging to the genus Escherichia
    Publication number: 20050181488
    Abstract: A method is disclosed for producing L-threonine using bacterium belonging to the genus Escherichia, wherein the bacterium has L-threonine productivity and has been modified to have enhanced expression of one or more of the following genes: glk, pgi, pfkA,, tpiA, gapA, pgk, eno, and pykA, which code for enzymes of glycolytic pathway.
    Type: Application
    Filed: February 8, 2005
    Publication date: August 18, 2005
    Inventors: Valery Akhverdian, Ekaterina Savrasova, Natalia Samsonova, Vladimir Ermishev, Irina Altman, Leonid Ptitsyn
  • Method for producing L-amino acid using bacterium of Enterobacteriaceae family, having nir operon inactivated
    Publication number: 20050069994
    Abstract: A method is provided for producing L-amino acid, such as L-arginine using a bacterium of Enterobacteriaceae family, particularly a bacterium belonging the genus Escherichia, with an inactivated nir operon.
    Type: Application
    Filed: August 27, 2004
    Publication date: March 31, 2005
    Inventors: Leonid Ptitsyn, Irina Altman, Sergey Smirnov, Natalia Samsonova, Vladimir Ermishev
  • Mutant N-acetylglutamate synthase and method for L-arginine production
    Publication number: 20050026258
    Abstract: L-arginine is produced using a bacterium belonging to the genus Escherichia harboring a mutant N-acetylglutamate synthase in which the amino acid sequence corresponding to positions from 15 to 19 in a wild type N-acetylglutamate synthase is replaced with any one of amino acid sequences of SEQ ID NOS: 1 to 4, and feedback inhibition by L-arginine is desensitized.
    Type: Application
    Filed: July 15, 2004
    Publication date: February 3, 2005
    Applicant: Ajinomoto Co., Inc.
    Inventors: Leonid Ptitsyn, Irina Altman, Sergey Smirnov, Yulia Rostova, Tatyana Yampolskaya, Tatyana Leonova, Mikhail Gusyatiner
  • L-arginine producing Escherichia coli and method of producing L-arginine
    Publication number: 20050026259
    Abstract: Arginine can be efficiently produced by cultivating Escherichia coli which has an ability to produce arginine and an ability to utilize acetate in a culture medium to produce and accumulate arginine in the medium, and collecting arginine from the medium.
    Type: Application
    Filed: August 25, 2004
    Publication date: February 3, 2005
    Applicant: Ajinomoto Co., Inc.
    Inventors: Mikhail Gusyatiner, Tatyana Leonova, Leonid Ptitsyn, Tatyana Yampolskaya