Abstract: Provided herein is a device for detecting the presence of pathogens in a sample and methods of use thereof. The device and method comprises one or more amplification components, an indicator, and a sensor (e.g., a pH sensitive polymer). Contacting a sample with the one or more amplification components, the indicator, and the sensor (e.g., a pH sensitive polymer) in a first region of the device and subjecting the sample to an amplification method may lead to a change in pH, releasing the indicator to flow towards a second region of the device, which generates a visually detectable signal and indicates the presence of a pathogen.

Abstract: The present invention relates to microfluidic cartridges that operate as closed systems. A microfluidic cartridge as described herein allows for the independent evaluation of multiple, isolated portions of a fluid sample (such as, e.g., a blood sample). In certain embodiments, each isolated portion has a predetermined volume. The present invention also relates to methods for simultaneously evaluating multiple, isolated portions of a fluid sample using a single cartridge.

Abstract: The cartridge for detecting a target analyte according to the present invention comprises a mainframe comprising a chamber, a passage connected to the chamber, and a valve connected to the passage; an elastic member located on a one side of the mainframe and covering the passage and the valve; and a subframe located on a front side of the elastic member, wherein the subframe has a pressure supply hole at a portion corresponding to the valve and supplies a pressure to the elastic member through the pressure supply hole.

Abstract: Various embodiments of the present invention provide microchannel and electrode configurations by which uniform electric current density within a microchannel is achieved. The invention provides this and other advantages.

Abstract: A light curing impression system comprising a light emitting tray that precisely distributes an optimal amount of curing light energy to internal, external and extra oral portions of the dental arch to cure impression material. The light curing impression system generally includes an LED light source, a light emitting impression tray, an activation module and impression material.

Abstract: A light curing dental system comprising a light emitting tray that precisely distributes an optimal amount of curing light energy to internal, external and extra oral portions of the dental arch to cure a dental material. The light curing dental system generally includes a light source, a light emitting dental tray, an activation module and a photocurable dental material.

Abstract: A light curing dental system comprising a light emitting tray that precisely distributes an optimal amount of curing light energy to internal, external and extra oral portions of the dental arch to cure a dental material. The light curing dental system generally includes a light source, a light emitting dental tray, an activation module and a photocurable dental material.

Abstract: A light curing impression system comprising a light emitting tray that precisely distributes an optimal amount of curing light energy to internal, external and extra oral portions of the dental arch to cure impression material. The light curing impression system generally includes an LED light source, a light emitting impression tray, an activation module and impression material.

Abstract: A light curing dental system comprising a light emitting tray that precisely distributes an optimal amount of curing light energy to internal, external and extra oral portions of the dental arch to cure a dental material. The light curing dental system generally includes a light source, a light emitting dental tray, an activation module and a photocurable dental material.