Patents by Inventor Leopold D'Espaux

Leopold D'Espaux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Yeast Cells and Methods for Producing Fatty Alcohols
    Publication number: 20230039548
    Abstract: The present invention provides for a genetically modified yeast cell comprising at least six or more of the following modifications: increased expression of Mus musculus fatty acid reductase, acetyl-CoA carboxylase, fatty acid synthase 1, fatty acid synthase 2, a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, and/or a desaturase encoded by OLE1, and reduced expression of DGA1, HFD1, ADH6, and/or GDH1. The present invention provides a method for constructing the genetically modified yeast cell, and a method for producing a fatty alcohol from the genetically modified yeast cell.
    Type: Application
    Filed: June 21, 2022
    Publication date: February 9, 2023
    Applicant: The Regents of the University of California
    Inventors: Leopold D'Espaux, Jay D. Keasling
  • Yeast cells and methods for producing fatty alcohols
    Patent number: 11365431
    Abstract: The present invention provides for a genetically modified yeast cell comprising at least six or more of the following modifications: increased expression of Mus musculus fatty acid reductase, acetyl-CoA carboxylase, fatty acid synthase 1, fatty acid synthase 2, a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, and/or a desaturase encoded by OLE1, and reduced expression of DGA1, HFD1, ADH6, and/or GDH1. The present invention provides a method for constructing the genetically modified yeast cell, and a method for producing a fatty alcohol from the genetically modified yeast cell.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: June 21, 2022
    Assignee: The Regents of the University of California
    Inventors: Leopold D'Espaux, Jay D. Keasling
  • Yeast Cells and Methods for Producing Fatty Alcohols
    Publication number: 20200231990
    Abstract: The present invention provides for a genetically modified yeast cell comprising at least six or more of the following modifications: increased expression of Mus musculus fatty acid reductase, acetyl-CoA carboxylase, fatty acid synthase 1, fatty acid synthase 2, a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, and/or a desaturase encoded by OLE1, and reduced expression of DGA1, HFD1, ADH6, and/or GDH1. The present invention provides a method for constructing the genetically modified yeast cell, and a method for producing a fatty alcohol from the genetically modified yeast cell.
    Type: Application
    Filed: February 10, 2020
    Publication date: July 23, 2020
    Applicant: The Regents of the University of California
    Inventors: Leopold D'Espaux, Jay D. Keasling
  • Yeast host cells and methods for producing fatty alcohols
    Patent number: 10557152
    Abstract: The present invention provides for a genetically modified yeast cell comprising at least six or more of the following modifications: increased expression of Mus musculus fatty acid reductase, acetyl-CoA carboxylase, fatty acid synthase 1, fatty acid synthase 2, a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, and/or a desaturase encoded by OLE1, and reduced expression of DGA1, HFD1, ADH6, and/or GDH1. The present invention provides a method for constructing the genetically modified yeast cell, and a method for producing a fatty alcohol from the genetically modified yeast cell.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: February 11, 2020
    Assignee: The Regents of the University of California
    Inventors: Leopold D'Espaux, Jay D. Keasling
  • Yeast Host Cells and Methods for Producing Fatty Alcohols
    Publication number: 20190136266
    Abstract: The present invention provides for a genetically modified yeast cell comprising at least six or more of the following modifications: increased expression of Mus musculus fatty acid reductase, acetyl-CoA carboxylase, fatty acid synthase 1, fatty acid synthase 2, a mutant of the bottleneck enzyme encoded by ACC1 insensitive to post-transcriptional and post-translational repression, and/or a desaturase encoded by OLE1, and reduced expression of DGA1, HFD1, ADH6, and/or GDH1. The present invention provides a method for constructing the genetically modified yeast cell, and a method for producing a fatty alcohol from the genetically modified yeast cell.
    Type: Application
    Filed: May 14, 2018
    Publication date: May 9, 2019
    Applicant: The Regents of the University of California
    Inventors: Leopold D'Espaux, Jay D. Keasling