Patents by Inventor Leopold N. Thunus

Leopold N. Thunus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of 4-amino-3-sulfonamido-pyridine, their preparation and use
    Patent number: 4244950
    Abstract: This invention relates to new derivatives of 4-amino-3-sulfonamido-pyridine having diuretic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which R.sub.1 represents hydrogen or an alkyl, cycloalkyl, carbamoyl or sulfonamido radical;R.sub.2 represents an alkyl, halogenoalkyl, cycloalkyl, alkenyl, alkynyl, hydroxyalkyl, alkoxyalkyl, phenyl (possibly substituted), phenylalkyl, diphenylmethyl, isobornyl, furfuryl, tetrahydrofurfuryl, dialkylaminoalkyl or heterocyclic radical; or R.sub.1 and R.sub.2 form together with the nitrogen atom a saturated heterocyclic radical; andX represents an alkoxy radical, an heterocyclic amino radical, or a secondary or tertiary amino radical having its first substituent selected from hydrogen and the alkyl and alkenyl groups, and its second substituent selected from the alkyl, alkenyl, alkynyl, hydroxyalkyl, diphenylmethyl, isorbornyl, furfuryl, tetrahydrofurfuryl, phenylalkyl and heterocyclic groups.
    Type: Grant
    Filed: January 24, 1979
    Date of Patent: January 13, 1981
    Assignee: A. Christiaens Societe Anonyme
    Inventors: Rene R. De Ridder, Andre H. Georges, Arlette Ghys, Charles L. Lapiere, Jacques E. Delarge, Leopold N. Thunus
  • Certain pyridine carboxamide derivatives
    Patent number: 4002629
    Abstract: This invention relates to compounds of the formula: ##STR1## wherein R.sub.1 in the 3- or 5-position is a carboxamido group whereas R.sub.2 in the 2-position is a 1-methyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.
    Type: Grant
    Filed: September 26, 1975
    Date of Patent: January 11, 1977
    Assignee: A. Christiaens Societe Anonyme
    Inventors: Jacques E. Delarge, Leopold N. Thunus, Charles-Leon Lapiere, Andre H. Georges
  • C-Piperazino-pyridine sulfonamides
    Patent number: 3991057
    Abstract: This invention relates to compounds of the formula: ##SPC1##Wherein R.sub.1 in the 3- or 5-position is preferably a substituted sulfonamido or a carboxamido group whereas R.sub.2 in the 2-, 4- or 6-position is preferably an alkyl- or hydroxyalkyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.
    Type: Grant
    Filed: April 11, 1974
    Date of Patent: November 9, 1976
    Assignee: A. Christiaens Societe Anonyme
    Inventors: Jacques E. Delarge, Leopold N. Thunus, Charles L. Lapiere, Andre H. Georges
  • 2-(4-Methyl-piperazino)-3 or 5 cyano pyridine
    Patent number: 3980652
    Abstract: This invention relates to compounds of the formula ##SPC1##Wherein R.sub.1 in the 3- or 5-position is a cyano group whereas R.sub.2 and in the 2-position is a N-methyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.
    Type: Grant
    Filed: September 26, 1975
    Date of Patent: September 14, 1976
    Assignee: A. Christiaens Societe Anonyme
    Inventors: Jacques E. Delarge, Leopold N. Thunus, Charles Leon Lapiere, Andre H. Georges