Patents by Inventor Leqian Yu

Leqian Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR GENERATING FORMATIVE PLURIPOTENT STEM CELLS COMPETENT FOR DIRECT PRIMORDIAL GERM CELL INDUCTION
    Publication number: 20230392125
    Abstract: Aspects of the present disclosure relate to methods for producing formative pluripotent stem cells (PSCs) by culturing cells in a medium that comprises a fibroblast growth factor (FGF) activator, a transforming growth factor beta (TGF-?) activator, and a WNT activator. Also provided are in vitro culture systems for producing the formative pluripotent stem cells.
    Type: Application
    Filed: October 19, 2021
    Publication date: December 7, 2023
    Applicant: The Board of Regents of The University of Texas System
    Inventors: Jun WU, Leqian YU
  • A Method of Preparing a Pluripotent Stem Cell Suitable for Differentiating into a Cardiomyocyte
    Publication number: 20200239847
    Abstract: The disclosure provides a method of preparing a pluripotent stem cell suitable for differentiating into a cardiomyocyte comprising (1) culturing at least one pluripotent stem cell on a low cell adhesion substrate to generate a dome-like colony; and (2) collecting a cell from the dome-like colony. The disclosure also provides a method of preparing a population of cardiomyocytes comprising inducing myocardial differentiation of a population of pluripotent stem cells prepared by the method described above.
    Type: Application
    Filed: October 17, 2018
    Publication date: July 30, 2020
    Applicant: Kyoto University
    Inventors: Li Liu, Leqian Yu, Junjun Li