Patents by Inventor Lesley A Howell

Lesley A Howell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of duocarmycin analogues
    Patent number: 9765077
    Abstract: A novel Fmoc protected duocarmycin subunit and utilization as a reagent in solid phase protein synthesis methodology. Also provided is a novel method of solid phase peptide synthesis, and in particular a method for the production of novel intermediates and novel monomeric and extended duocarmycin analogues having amino acid substituents.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: September 19, 2017
    Assignee: University of East Anglia
    Inventors: Michael J Stephenson, Lesley A Howell, Mark Searcey
  • Synthesis of Duocarmycin Analogues
    Publication number: 20160347753
    Abstract: A novel Fmoc protected duocarmycin subunit and utilisation as a reagent in solid phase protein synthesis methodology. Also provided is a novel method of solid phase peptide synthesis, and in particular a method for the production of novel intermediates and novel monomeric and extended duocarmycin analogues having amino acid substituents.
    Type: Application
    Filed: May 29, 2015
    Publication date: December 1, 2016
    Inventors: Michael J Stephenson, Lesley A Howell, Mark Searcey