Abstract: Novel 1 2(H)-phthalazones are disclosed along with a method of treating either allergic rihinitis or bronchial asthma by the administration to a mammal an effective amount of a compound of the formula: ##STR1## wherein R.sub.1 is hydrogen, hydroxyl, C.sub.1 -C.sub.4 alkoxy, or C.sub.1 -C.sub.4 alkylthio,R.sub.2 is ##STR2## or 1-pyrrolidinyl, R.sub.3 and R.sub.4 are independently hydrogen or C.sub.1 -C.sub.4 alkyl,X is CH.sub.2, O or NR.sub.5,Y is ethylene or ethenylene,R.sub.5 is hydrogen or C.sub.1 -C.sub.4 alkyl,n is 2, 3 or 4,and all stereoisomeric forms and pharmaceutical acceptable addition salts thereof.

Abstract: A compound useful as anti-inflammatory agents in warm-blooded animals of the formula ##STR1## wherein X is a member of the class of ethylene and ethenyl and is substituted for hydrogen in the sixth or seventh position of the 1(2H)-phthalazinone ringY is a member of the class of hydrogen and hydroxylR.sub.1 is a member of the class of hydrogen, alkyl, alkoxy, hydroxyl, halogen, nitro, --NR.sub.3 R.sub.4, --COR.sub.5 and --O--A wherein A is a mineral acid residue which with --O-- forms an ester or the alkali metal salt of said ester,R.sub.2 is a member of the class of hydrogen, alkyl, phenyl, substituted phenyl, heteroaryl, hydroxyalkylene, polyhydroxyalkylene, aminoalkylene, alkylaminoalkylene, and carboxyalkylene,R.sub.3, R.sub.4 are independently from the class of hydrogen, alkyl, aminoalkylene or alkylaminoalkylene,R.sub.5 is a member of the class of OR.sub.