Patents by Inventor Leslie A. Geddes

Leslie A. Geddes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7569018
    Abstract: An auditory pulse monitor for noninvasively detecting the amplitude of arterial pulses on a beat-by-beat basis. A light-weight optical sensor including a light source and photodetector is adapted for application to the skin surface of a subject over a tissue bed containing an arterial supply. The photodetector generates an output signal proportional to the amplitude of an arterial pulse, and an electronic circuit connected to the photodetector generates a signal having a frequency proportional to the photodetector output signal level. A speaker or other audio indicator connected to the electronic circuit generates an audible tone indicating the amplitude of the arterial pulse. Another aspect of the invention is an improvement in automated or automatic external defibrillators (AEDs). An AED is disclosed which optically detects arterial pulses after delivering a defibrillation shock and signals the need for CPR if it detects inadequate cardiac pumping following successful defibrillation.
    Type: Grant
    Filed: February 18, 2003
    Date of Patent: August 4, 2009
    Assignee: Purdue Research Foundation
    Inventors: Leslie A. Geddes, Kirk S. Foster, Rebecca A. Roeder
  • Patent number: 7164938
    Abstract: An optical noninvasive vital sign monitor comprising a reflectance-type optical sensor within a pressurizable capsule retained by a headband, the capsule having an optically transparent or translucent inner wall adapted for placement against a subject's forehead. The optical sensor is mounted on the inside surface of the pressurizable capsule's inner wall, which contacts the subject's forehead during use, and includes a light source and a photodetector aimed toward the inside surface of the inner capsule wall. One embodiment of the vital sign monitor includes optical oscillometric circuit means responsive to an output signal from the optical sensor for determining systolic pressure, mean pressure and diastolic pressure during a transition in capsule pressure between a pressure greater than normal systolic pressure and a pressure less than normal diastolic pressure.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: January 16, 2007
    Assignee: Purdue Research Foundation
    Inventors: Leslie A. Geddes, Rebecca A. Roeder, Kirk S. Foster, George P. Graber
  • Patent number: 7096059
    Abstract: An electrocardiography device and method that is able to obtain the electrocardiogram of a freely moving animal. The device and method utilizes at least two catheters to obtain the electrical signals from the heart of the animal being tested. The catheters are filled with an electrically-conductive, physiological solution and are used in combination with at least two test leads that are able to transfer the electrical signals from the animal to an ECG monitoring device. The device and method also allows for fluids to flow through the catheters to other devices such as a blood sampler controller and/or an infusion pump.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: August 22, 2006
    Assignee: Bioanalytical Systems, Inc.
    Inventors: Leslie A. Geddes, Candice B. Kissinger, Joseph A. Bougher, Stephen J. Clevenger
  • Patent number: 7014611
    Abstract: An oscillometric, noninvasive blood pressure monitor comprising an inflatable cuff adapted for placement around a body member, a pump for cuff inflation, a pressure transducer connected to the cuff, means for detecting oscillations in arterial pressure occurring during a transition in cuff pressure between a pressure greater than normal systolic pressure and a pressure less than normal diastolic pressure, and a blood pressure measurement circuit which is capable of determining the maximum amplitude (Am) of the oscillations, identifying mean cuff pressure (Pm) as the coincident value of the cuff-pressure signal from the pressure transducer, and determining systolic pressure as a function of both Am and Pm. In accordance with one aspect of the invention, the blood pressure monitor has an optical sensor including a light source and photodetector optically coupled to the body member proximate to the cuff.
    Type: Grant
    Filed: June 24, 2004
    Date of Patent: March 21, 2006
    Assignee: Purdue Research Foundation
    Inventors: Leslie A. Geddes, Rebecca A. Roeder
  • Publication number: 20050283082
    Abstract: An optical noninvasive vital sign monitor comprising a reflectance-type optical sensor within a pressurizable capsule retained by a headband, the capsule having an optically transparent or translucent inner wall adapted for placement against a subject's forehead. The optical sensor is mounted on the inside surface of the pressurizable capsule's inner wall, which contacts the subject's forehead during use, and includes a light source and a photodetector aimed toward the inside surface of the inner capsule wall. One embodiment of the vital sign monitor includes optical oscillometric circuit means responsive to an output signal from the optical sensor for determining systolic pressure, mean pressure and diastolic pressure during a transition in capsule pressure between a pressure greater than normal systolic pressure and a pressure less than normal diastolic pressure.
    Type: Application
    Filed: June 20, 2005
    Publication date: December 22, 2005
    Inventors: Leslie Geddes, Rebecca Roeder, Kirk Foster, George Graber
  • Patent number: 6801798
    Abstract: A member-illuminating cuff for measurement of systolic, mean and diastolic pressure, oxygen saturation, pulse and respiratory rate in small body members, comprising a hinged cuff housing, one or more light sources mounted on a first section of the housing, a photodetector mounted on a second section of the housing, and a disposable, inflatable cuff adapted to fit within the cuff housing and around a body member placed therein.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: October 5, 2004
    Assignee: Purdue Research Foundation
    Inventors: Leslie A. Geddes, Kirk S. Foster, William E. Schoenlein, Rebecca A. Roeder, Claude B. Harrington
  • Publication number: 20040006280
    Abstract: The present invention provides an electrocardiography device that is able to obtain the electrocardiogram of a freely moving animal. The present invention utilizes at least two catheters to obtain the electrical signals from the heart of the animal being tested. The catheters are filled with an electrically-conductive, physiological solution and are used in combination with at least two test leads that are able to transfer the electrical signals from the animal to an ECG monitoring device. The present invention also allows for fluids to flow through the catheters to other devices such as a blood sampler controller and/or an infusion pump.
    Type: Application
    Filed: July 2, 2003
    Publication date: January 8, 2004
    Applicant: Bioanalytical Systems, Inc., an Indiana corporation
    Inventors: Leslie A. Geddes, Candice B. Kissinger, Joseph A. Bougher, Stephen J. Clevenger
  • Patent number: 6546287
    Abstract: A controlled-power defibrillator and method of defibrillation for automatically compensating for changes in patient resistance during delivery of a defibrillation pulse. A switching power converter is connected between a storage capacitor and a pair of electrodes adapted for connection to a patient's body, either internally or externally. A closed-loop power control circuit is operatively connected to the power converter for control of the power delivered to the patient, the power control circuit generating a target voltage signal for the storage capacitor, the target voltage signal having a defined relationship with the waveform of the power desired to be delivered to the patient. The power control circuit monitors the actual voltage on the storage capacitor and adjusts the delivery of power to the patient as a function of the difference between desired and actual storage capacitor voltage.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: April 8, 2003
    Assignee: Purdue Research Foundation
    Inventors: William J. Havel, Joe D. Bourland, Leslie A. Geddes, Willis A. Tacker, Darrell O. Wagner
  • Publication number: 20030065379
    Abstract: A tissue graft construct and method for repairing the inner linings of damaged or diseased vertebrate vessels is described. The method comprises the steps of positioning a tissue graft construct within a blood vessel at a site in need of repair. The tissue graft construct comprises a stent (3) covered with submucosal tissue (4) wherein the stent (3) is formed for receiving the distal end of a catheter (1) having an inflatable balloon (2).
    Type: Application
    Filed: November 4, 2002
    Publication date: April 3, 2003
    Inventors: Charles F. Babbs, Neal F. Fearnot, Stephen F. Badylak, Leslie A. Geddes, Michael C. Hiles, Joe D. Bourland
  • Publication number: 20030036690
    Abstract: A member-illuminating cuff for measurement of systolic, mean and diastolic pressure, oxygen saturation, pulse and respiratory rate in small body members, comprising a hinged cuff housing, one or more light sources mounted on a first section of the housing, a photodetector mounted on a second section of the housing, and a disposable, inflatable cuff adapted to fit within the cuff housing and around a body member placed therein.
    Type: Application
    Filed: June 20, 2002
    Publication date: February 20, 2003
    Inventors: Leslie A. Geddes, Kirk S. Foster, William E. Schoenlein, Rebecca A. Roeder, Claude B. Harrington
  • Patent number: 6475232
    Abstract: A tissue graft construct and method for repairing the inner linings of damaged or diseased vertebrate vessels is described. The method comprises the steps of positioning a tissue graft construct within a blood vessel at a site in need of repair. The tissue graft construct comprises a stent (3) covered with submucosal tissue (4) wherein the stent (3) is formed for receiving the distal end of a catheter (1) having an inflatable balloon (2).
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: November 5, 2002
    Assignee: Purdue Research Foundation
    Inventors: Charles F. Babbs, Neal F. Fearnot, Stephen F. Badylak, Leslie A Geddes, Michael C. Hiles, Joe D. Bourland
  • Patent number: 6187039
    Abstract: An easy-to-produce and mechanically strong tube of an implantable submucosal tissue has been developed which is manufactured in any desired length, wall thickness, or diameter. The construct produced by the method of the invention may be used as grafts for arteries, veins, ureters, urethras, shunts, or in any application where a compliant, tissue-compatible tube is needed. The manufacture of the submucosal tissue prosthesis generally involves wrapping a first sheet of submucosal tissue (60) and a second sheet of submucosal tissue (70) around a mandrel (50), wherein the first end (74) and the second opposite end (76) of the second sheet of submucosal tissue (70) are sutured together with sutures (78). The submucosal tissue is compressed and dried on the mandrel (50) before removing the construct by pulling on a first end (54) and a second end (56) of a water permeable tape to unwind the tape and thus release the construct for eventual use.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: February 13, 2001
    Assignee: Purdue Research Foundation
    Inventors: Michael C. Hiles, Umesh H. Patel, Leslie A. Geddes, Stephen F. Badylak
  • Patent number: 6126686
    Abstract: A method for preparing vascular valves from submucosal tissue is described. Both bicuspid and tricuspid valve constructs are described. The bicuspid constructs can be formed with or without a supporting stent. The tricuspid constructs are formed by fixing submucosal tissue to a supporting stent, folding the submucosal tissue, and forming the valve commissures from the folded submucosal tissue by cutting along the folds. The artificial vascular valves are useful for replacing damaged or diseased valves of a warm-blooded vertebrate.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: October 3, 2000
    Assignee: Purdue Research Foundation
    Inventors: Stephen F. Badylak, Arthur C. Coffey, Leslie A. Geddes, Michael C. Hiles, James Hong, Rebecca Roeder
  • Patent number: 6096347
    Abstract: The use of submucosal tissue of a warm blooded vertebrate to manufacture a tissue graft composition that induces the formation of endogenous cardiac tissues in vivo upon contact of the cardiac tissues with the manufactured composition.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: August 1, 2000
    Assignee: Purdue Research Foundation
    Inventors: Leslie A. Geddes, Stephen F. Badylak, Robert G. Matheny, William E. Schoenlein, Fred J. Obermiller, William J. Havel
  • Patent number: 5916239
    Abstract: A closed-loop, variable-frequency, vagal-stimulation apparatus for control of ventricular rate during atrial fibrillation. In one embodiment the apparatus includes a stimulator applied to the left vagus nerve and a controller programmed to automatically and continuously adjust the vagal stimulation frequency as a function of the difference between actual and desired ventricular excitation rates. In a second embodiment the apparatus includes a vagal nerve stimulator and a controller which automatically adjusts the vagal stimulation frequency as a function of the difference between ventricular excitation rate and arterial pulse rate in order to eliminate or minimize pulse deficit.
    Type: Grant
    Filed: November 24, 1997
    Date of Patent: June 29, 1999
    Assignee: Purdue Research Foundation
    Inventors: Leslie A. Geddes, Tarek Elabbady, William E. Schoenlein, Matthew Waninger, Joe D. Bourland
  • Patent number: 5690681
    Abstract: A closed-loop variable frequency vagal stimulation apparatus for control of ventricular rate during atrial fibrillation. In one embodiment the apparatus includes a stimulator applied to the left vagus nerve and a proportional controller programmed to automatically and continuously adjust the vagal stimulation frequency proportionally as a function of the difference between actual and desired ventricular excitation rates. In a second embodiment the apparatus includes a vagal nerve stimulator and a controller which automatically adjusts the vagal stimulation frequency as a function of the difference between ventricular excitation rate and arterial pulse rate in order to eliminate or minimize pulse deficit.
    Type: Grant
    Filed: March 29, 1996
    Date of Patent: November 25, 1997
    Assignee: Purdue Research Foundation
    Inventors: Leslie A. Geddes, Tarek Elabbady, William E. Schoenlein, Matthew Waninger, Joe D. Bourland
  • Patent number: 5573784
    Abstract: Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa delaminated from both the tunica muscularis and at least the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.
    Type: Grant
    Filed: April 18, 1995
    Date of Patent: November 12, 1996
    Assignees: Purdue Research Foundation, Methodist Hospital of Indiana, Inc.
    Inventors: Stephen F. Badylak, Leslie A. Geddes, K. Donald Shelbourne, Gary C. Lantz, Arthur C. Coffey
  • Patent number: 5445833
    Abstract: Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa, and basilar mucosa tissue delaminated from the tunica muscularis and the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.
    Type: Grant
    Filed: December 15, 1993
    Date of Patent: August 29, 1995
    Assignees: Purdue Research Foundation, Methodist Hospital of Indiana, Inc.
    Inventors: Stephen F. Badylak, Leslie A. Geddes, K. Donald Shelbourne, Gary C. Lantz, Arthur C. Coffey
  • Patent number: 5372821
    Abstract: Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa and basilar mucosa tissue delaminated from the tunica muscularis and the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.
    Type: Grant
    Filed: December 15, 1993
    Date of Patent: December 13, 1994
    Assignee: Purdue Research Foundation
    Inventors: Stephen F. Badylak, Leslie A. Geddes, K. Donald Shelbourne, Gary C. Lantz, Arthur C. Coffey
  • Patent number: 5354274
    Abstract: A device is provided for facilitating oral administration of unit dosages of liquid formulations, particularly to pediatric and geriatric patients. Sealed cartridges containing unit doses of liquid nutrients or medications can be locked into the device and at the same time, breached so that the contained-liquid formulation can flow from the cartridge into a hollow nipple for facile oral consumption. The liquid formulation-contained sealed cartridge includes a container having a side wall collapsible responsive to withdrawal of liquid from the hollow nipple.
    Type: Grant
    Filed: August 20, 1992
    Date of Patent: October 11, 1994
    Assignees: Methodist Hospital of Indiana, Inc., Purdue Research Foundation
    Inventors: Robert J. Demeter, Stephen F. Badylak, Kirk S. Foster, Leslie A. Geddes