Patents by Inventor Leslie A. Hickle

Leslie A. Hickle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccines
    Patent number: 8168201
    Abstract: The present invention relates to compositions for inducing immune responses, including an antigen and a promiscuous T-cell epitope. Also provided are methods of inducing immune responses in hosts, comprising administering compositions comprising antigens and promiscuous T-cell epitopes to the host.
    Type: Grant
    Filed: April 3, 2007
    Date of Patent: May 1, 2012
    Assignee: Pfizer Canada Inc.
    Inventors: Leslie Hickle, Abraham Anderson, Robert C. Brown, Paul Budworth, Gordana Djordjevic, Scott Kroken, Peter Luginbuhl, Toby Richardson, Genevieve Hansen
  • VACCINES
    Publication number: 20070286871
    Abstract: The present invention relates to compositions for inducing immune responses, including an antigen and a promiscuous T-cell epitope. Also provided are methods of inducing immune responses in hosts, comprising administering compositions comprising antigens and promiscuous T-cell epitopes to the host.
    Type: Application
    Filed: April 3, 2007
    Publication date: December 13, 2007
    Applicant: Diversa Corporation
    Inventors: Leslie Hickle, Abraham Anderson, Robert Brown, Paul Budworth, Gordana Djordjevic, Scott Kroken, Peter Luginbuhl, Toby Richardson, Genevieve Hansen
  • Materials and methods for the control of calliphoridae pests
    Patent number: 6056953
    Abstract: Methods and compositions for the control of pests of the family Calliphoridae are described. Specifically, Bacillus thuringiensis (B.t.) isolates having anti-calliphorid activity are disclosed. Also described are recombinant hosts which express B.t. genes coding for pesticidal toxins. The B.t. isolates and recombinant proteins are shown to be useful in a method for controlling calliphorids including screw-worms and the sheep blowfly.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: May 2, 2000
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, Jewel Payne
  • Materials and methods for the control of calliphoridae pests
    Patent number: 5888503
    Abstract: Methods and compositions for the control of pests of the family Calliphoridae are described. Specifically, Bacillus thuringiensis (B.t.) isolates having anti-calliphorid activity are disclosed. Also described are recombinant hosts which express B.t. genes coding for pesticidal toxins. The B.t. isolates and recombinant proteins are shown to be useful in a method for controlling calliphorids including screw-worms and the sheep blowfly.
    Type: Grant
    Filed: May 14, 1997
    Date of Patent: March 30, 1999
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, Jewel Payne
  • Bacillus thuringiensis isolates active against phthiraptera pests
    Patent number: 5273746
    Abstract: Methods and compositions for the control of lice are described. Specifically, Bacillus thuringiensis (B.t.) isolates having anti-lice activity are disclosed. Also described are recombinant hosts which express B.t. genes coding for pesticidal toxins. The B.t. isolates and recombinant proteins are shown to be useful in a method for controlling lice including the sheep louse.
    Type: Grant
    Filed: January 29, 1992
    Date of Patent: December 28, 1993
    Assignee: Mycogen Corporation
    Inventors: Jewel M. Payne, Leslie A. Hickle
  • Compositions and methods for the control of flukes
    Patent number: 5262399
    Abstract: Methods and compositions for the control of flukes are described. Specifically, Bacillus thuringiensis (B.t.) isolates having flukicidal activity are disclosed. Also described are recombinant hosts which express B.t. genes coding for flukicidal toxins. The B.t. isolates and recombinant proteins are shown to be useful in a method for controlling flukes including the liver fluke.
    Type: Grant
    Filed: March 27, 1991
    Date of Patent: November 16, 1993
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, August J. Sick, George E. Schwab, Kenneth E. Narva, Jewel M. Payne
  • Use of a Bacillus thuringiensis microbe for controlling lesser mealworm, Alphitobius diaperinus
    Patent number: 5106620
    Abstract: The subject invention concerns the use of a novel and useful bioinsecticide against the lesser mealworm (Alphitobius diaperinus). The lesser mealworm is a devastating pest in the poultry industry. The bioinsecticide of the subject invention is a novel B. thuringiensis microbe referred to as B.t. PS122D3, or mutants thereof. The spores or toxin crystals of this microbe are useful to control the lesser mealworm in various environments.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: April 21, 1992
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, Gregory A. Bradfisch, Jewel M. Payne
  • Use of a Bacillus thuringiensis microbe for controlling lesser meal-worm, Alphitobius diaperinus
    Patent number: 5100665
    Abstract: The subject invention concerns the use of a novel and useful bioinsecticide against the lesser mealworm (Alphitobius diaperinus). The lesser mealworm is a devastating pest in the poultry industry. The bioinsecticide of the subject invention is a novel B. thuringiensis microbe referred to as B.t. PS86B1, or mutants thereof. The spores or toxin crystals of this microbe are useful to control the lesser mealworm in various environments.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: March 31, 1992
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, Gregory A. Bradfisch, Jewel M. Payne
  • Use of a bacillus thuringiensis microbe for controlling lesser mealworm, alphitobius diaperinus
    Patent number: 5098705
    Abstract: The subject invention concerns the use of a novel and useful bioinsecticide against the lesser mealworm (Alphitobius diaperinus). The lesser mealworm is a devastating pest in the poultry industry. The bioinsecticide of the subject invention is a novel B. thuringiensis microbe referred to as B.t. PS40D1, or mutants thereof. The spores or toxin crystals of this microbe are useful to control the lesser mealworm in various environments.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: March 24, 1992
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, Gregory A. Bradfisch, Jewel M. Payne
  • Use of a Bacillus thuringiensis microbe for controlling lesser mealworm, Alphitobius diaperinus
    Patent number: 5093119
    Abstract: The subject invention concerns the use of a novel and useful bioinsecticide against the lesser mealworm (Alphitobius diaperinus). The lesser mealworm is a devastating pest in the poultry industry. The bioinsecticide of the subject invention is a novel B. thuringiensis microbe referred to as B.t. MT 104, or mutants thereof. The spores or toxin crystals of this microbe are useful to control the lesser mealworm in various environments.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: March 3, 1992
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, Gregory A. Bradfisch, Jewel M. Payne
  • Use of Bacillus thuringiensis microbe for controlling lesser mealworm, Alphitobius diaperinus
    Patent number: 5064648
    Abstract: The subject invention concerns the use of a novel and useful bioinsecticide against the lesser mealworm (Alphitobius diaperinus). The lesser mealworm is a devasting pest in the poultry industry. The bioinsecticide of the subject invention is a novel B. thuringiensis microbe referred to a B.t. PS43F, or mutants thereof. The spores or toxin crystals of this microbe are useful to control the lesser mealworm in various environments.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: November 12, 1991
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, Gregory A. Bradfisch, August J. Sick