Patents by Inventor Leslie Ann Greene

Leslie Ann Greene has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF THREONYL-TRNA SYNTHETASES
    Publication number: 20130129704
    Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
    Type: Application
    Filed: April 27, 2011
    Publication date: May 23, 2013
    Applicants: PANGU BIOPHARMA LIMITED, ATYR PHARMA, INC.
    Inventors: Leslie Ann Greene, Kyle P. Chiang, Fei Hong, Alain Philippe Vasserot, Wing-Sze Lo, Jeffry Dean Watkins, Cheryl L. Quinn, John D. Mendlein
  • AMINO ACYL TRNA SYNTHETASES FOR MODULATING INFLAMMATION
    Publication number: 20130108630
    Abstract: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
    Type: Application
    Filed: December 10, 2010
    Publication date: May 2, 2013
    Inventors: Jeffry Dean Watkins, Alain Philippe Vasserot, Leslie Ann Greene, Ryan Andrew Adams, Kyle P. Chiang, Wei Zhang, Kristi Helen Piehl, Fei Hong, Alina He
  • Compositions and methods comprising glycyl-tRNA synthetases having non-canonical biological activities
    Patent number: 8404471
    Abstract: Isolated glycyl-tRNA synthetase polypeptides and polynucleotides having non-canonical biological activities are provided, as well as compositions and methods related thereto.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: March 26, 2013
    Assignee: aTyr Pharma, Inc.
    Inventors: Leslie Ann Greene, Ryan Andrew Adams, Fei Hong, Ji Zhao, Eva Rebecka Stephanie Armour, Kristi Helen Piehl
  • Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities
    Patent number: 8404242
    Abstract: Isolated histidyl-tRNA synthetase splice variant polynucleotides and polypeptides having non-canonical biological activities are provided, as well as compositions and methods related thereto.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: March 26, 2013
    Assignees: aTyr Pharma, Inc., Pangu BioPharma Limited
    Inventors: Jie Zhou, Ching Fun Lau, Zhiwen Xu, Wing Sze Lo, Kristi Helen Piehl, Leslie Ann Greene
  • AMINOACYL TRNA SYNTHETASES FOR MODULATING HEMATOPOIESIS
    Publication number: 20120064082
    Abstract: Hematopoietic-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof, as well as compositions comprising related agents such as antibodies and other binding agents. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of hematopoiesis.
    Type: Application
    Filed: June 16, 2011
    Publication date: March 15, 2012
    Applicant: ATYR PHARMA, INC.
    Inventors: Jeffry Dean Watkins, Alain P. Vasserot, Rajesh Belani, Leslie Ann Greene, Ryan Andrew Adams
  • POLYPEPTIDE STRUCTURAL MOTIFS ASSOCIATED WITH CELL SIGNALING ACTIVITY
    Publication number: 20120004185
    Abstract: Isolated polypeptides comprising or consisting essentially of specific structural motifs (e.g., three ?-sheets and two ?-helices) are provided, wherein the polypeptides exhibit at least one cell signaling and/or other non-canonical activity of biological relevance. Also provided are polynucleotides encoding such polypeptides, binding agents that bind such polypeptides, analogs, variants and fragments of such polypeptides, etc., as well as compositions and methods of identifying and using any of the foregoing.
    Type: Application
    Filed: February 26, 2010
    Publication date: January 5, 2012
    Applicant: ATYR PHARMA, INC.
    Inventor: Leslie Ann Greene
  • AMINOACYL TRNA SYNTHETASES FOR MODULATING HEMATOPOIESIS
    Publication number: 20110150885
    Abstract: Hematopoietic-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof, as well as compositions comprising related agents such as antibodies and other binding agents. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of hematopoiesis.
    Type: Application
    Filed: December 10, 2010
    Publication date: June 23, 2011
    Applicant: ATYR PHARMA, INC.
    Inventors: Jeffry Dean Watkins, Alain P. Vasserot, Rajesh Belani, Leslie Ann Greene, Ryan Andrew Adams
  • COMPOSITIONS AND METHODS COMPRISING HISTIDYL-TRNA SYNTHETASE SPLICE VARIANTS HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES
    Publication number: 20100297149
    Abstract: Isolated histidyl-tRNA synthetase splice variant polynucleotides and polypeptides having non-canonical biological activities are provided, as well as compositions and methods related thereto.
    Type: Application
    Filed: March 16, 2010
    Publication date: November 25, 2010
    Applicant: aTyr Pharma, Inc.
    Inventors: Jie Zhou, Ching Fun Lau, Zhiwen XU, Wing Sze Lo, Kristi Helen Piehl, Leslie Ann Greene
  • COMPOSITIONS AND METHODS COMPRISING GLYCYL-tRNA SYNTHETASES HAVING NON-CANONICAL BIOLOGICAL ACTIVITIES
    Publication number: 20100028352
    Abstract: Isolated glycyl-tRNA synthetase polypeptides and polynucleotides having non-canonical biological activities are provided, as well as compositions and methods related thereto.
    Type: Application
    Filed: June 26, 2009
    Publication date: February 4, 2010
    Applicant: ATYR PHARMA, INC.
    Inventors: Leslie Ann Greene, Ryan Andrew Adams, Fei Hong, Ji Zhao, Eva Rebecka Stephanie Armour, Kristi Helen Piehl