Patents by Inventor Leslie Bethards Friedrich

Leslie Bethards Friedrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene encoding a protein involved in the signal transduction cascade leading to systemic acquired resistance in plants
    Publication number: 20020152499
    Abstract: The invention concerns the location and characterization of a gene (designated NIM1) that is a key component of the SAR pathway and that in connection with chemical and biological inducers enables induction of SAR gene expression and broad spectrum disease resistance in plants. The invention further concerns transformation vectors and processes for overexpressing the NIM1 gene in plants. The transgenic plants thus created have broad spectrum disease resistance.
    Type: Application
    Filed: February 19, 2002
    Publication date: October 17, 2002
    Inventors: John Andrew Ryals, Terrence Patrick Delaney, Leslie Bethards Friedrich, Kristianna Baldwin Weymann, Kay Ann Lawton, Daniel Murray Ellis, Scott Joseph Uknes, Taco Peter Jesse, Pieter Vos
  • Method for protecting plants
    Publication number: 20020133846
    Abstract: The present invention concerns a method of protecting plants from pathogen attack through synergistic disease resistance attained by applying a conventional microbicide to immunomodulated plants. Immunomodulated plants are those in which SAR is activated and are therefore referred to as “SAR-on” plants. Immunomodulated plants may be provided in at least three different ways: by applying to plants a chemical inducer of SAR such as BTH, INA, or SA; through a selective breeding program based on constitutive expression of SAR genes and/or a disease-resistant phenotype; or by transforming plants with one or more SAR genes such as a functional form of the NIM1 gene. By concurrently applying a microbicide to an immunomodulated plant, disease resistance is unexpectedly synergistically enhanced; i.e., the level of disease resistance is greater than the expected additive levels of disease resistance.
    Type: Application
    Filed: December 12, 2001
    Publication date: September 19, 2002
    Inventors: John Andrew Ryals, Leslie Bethards Friedrich, Scott Joseph Uknes, Antonio Molina-Fernandez, Kay Ann Lawton
  • Gene encoding a protein involved in the signal transduction cascade leading to systemic acquired resistance in plants
    Patent number: 6091004
    Abstract: The invention concerns the location and characterization of a gene (designated NIM1) that is a key component of the SAR pathway and that in connection with chemical and biological inducers enables induction of SAR gene expression and broad spectrum disease resistance in plants. The invention further concerns transformation vectors and processes for overexpressing the NIM1 gene in plants. The transgenic plants thus created have broad spectrum disease resistance.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: July 18, 2000
    Assignee: Novartis Finance Corporation
    Inventors: John Andrew Ryals, Terrence Patrick Delaney, Leslie Bethards Friedrich, Kristianna Baldwin Weymann, Kay Ann Lawton, Daniel Murray Ellis, Scott Joseph Uknes, Taco Peter Jesse, Pieter Vos
  • Method for protecting plants
    Patent number: 6031153
    Abstract: The present invention concerns a method of protecting plants from pathogen attack through synergistic disease resistance attained by applying a conventional microbicide to immunomodulated plants. Immunomodulated plants are those in which SAR is activated and are therefore referred to as "SAR-on" plants. Immunomodulated plants may be provided in at least three different ways: by applying to plants a chemical inducer of SAR such as BTH, INA, or SA; through a selective breeding program based on constitutive expression of SAR genes and/or a disease-resistant phenotype; or by transforming plants with one or more SAR genes such as a functional form of the NIM1 gene. By concurrently applying a microbicide to an immunomodulated plant, disease resistance is unexpectedly synergistically enhanced; i.e., the level of disease resistance is greater than the expected additive levels of disease resistance.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: February 29, 2000
    Assignee: Novartis AG
    Inventors: John Andrew Ryals, Leslie Bethards Friedrich, Scott Joseph Uknes, Antonio Molina-Fernandez, Wilhelm Ruess, Gertrude Knauf-Beiter, Ruth Beatrice Kung, Helmut Kessmann, Michael Oostendorp