Patents by Inventor Leslie E Mace
Leslie E Mace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11538569Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.Type: GrantFiled: July 31, 2018Date of Patent: December 27, 2022Assignee: Freespira. Inc.Inventors: Leslie E. Mace, Elizabeth K. Siegelman, Debra L. Reisenthel, Simon W. H. Thomas
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Publication number: 20220270739Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.Type: ApplicationFiled: May 11, 2022Publication date: August 25, 2022Inventors: Leslie E. MACE, Elizabeth K. SIEGELMAN, Debra L. REISENTHEL, Simon W.H. THOMAS
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Patent number: 10175254Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.Type: GrantFiled: July 16, 2014Date of Patent: January 8, 2019Assignee: PALO ALTO HEALTH SCIENCES, INC.Inventors: Leslie E. Mace, Elizabeth K. Siegelman, Debra L. Reisenthel, Simon W. H. Thomas
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Publication number: 20180335440Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.Type: ApplicationFiled: July 31, 2018Publication date: November 22, 2018Inventors: Leslie E. MACE, Elizabeth K. SIEGELMAN, Debra L. REISENTHEL, Simon W.H. THOMAS
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Publication number: 20160245830Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.Type: ApplicationFiled: July 16, 2014Publication date: August 25, 2016Inventors: Leslie E. MACE, Elizabeth K. SIEGELMAN, Debra L. REISENTHEL, Simon W.H. THOMAS
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Patent number: 7897109Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical-signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.Type: GrantFiled: April 24, 2001Date of Patent: March 1, 2011Assignee: RIC Investments, LLCInventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke
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Patent number: 7833480Abstract: Apparatus or systems which employ luminescence-quenching to produce a signal indicative of oxygen concentration.Type: GrantFiled: March 28, 2003Date of Patent: November 16, 2010Assignee: RIC Investments, Inc.Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson
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Publication number: 20100036272Abstract: A system (300) for measuring a metabolic parameter. The system includes an integrated airway adapter (20, 100, 200) capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.Type: ApplicationFiled: January 31, 2008Publication date: February 11, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Leslie E. Mace, Joseph A. Orr, David R. Rich, Michael B. Jaffe, Jason Alderete
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Patent number: 7335164Abstract: An integrated airway adapter capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.Type: GrantFiled: April 24, 2001Date of Patent: February 26, 2008Assignee: NTC Technology, Inc.Inventors: Leslie E. Mace, Lawrence L. Labuda, Perry R. Blazewicz, David R. Rich, Michael B. Jaffe, Joseph A. Orr, Scott A. Kofoed
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Patent number: 7004168Abstract: A face mask including a gas monitoring capability for improved patient management in combination with improved efficiency of supplemental oxygen delivery to the patient is provided. The face mask of the present invention is configured to direct substantially all of the inspiratory and expiratory gas streams to and from the patient through a gas measuring device and to efficiently deliver supplemental oxygen. As such, the face mask permits measurement of both oral and nasal gas exchange.Type: GrantFiled: August 29, 2002Date of Patent: February 28, 2006Assignee: Respironics, Inc.Inventors: Leslie E Mace, David R Rich, Randall J Terry, John A Triunfo, Jr., Anthony T Pierry, Michael J. R. Polson
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Patent number: 6815211Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.Type: GrantFiled: August 4, 1998Date of Patent: November 9, 2004Assignee: NTC TechnologyInventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Gamal-Eddin Khalil
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Publication number: 20040013570Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical-signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.Type: ApplicationFiled: April 24, 2001Publication date: January 22, 2004Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke
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Patent number: 6632402Abstract: Apparatus or systems which employ luminescence-quenching to produce a signal indicative of oxygen concentration.Type: GrantFiled: January 24, 2001Date of Patent: October 14, 2003Assignee: NTC Technology Inc.Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson
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Publication number: 20030190262Abstract: Apparatus or systems which employ luminescence-quenching to produce a signal indicative of oxygen concentration.Type: ApplicationFiled: March 28, 2003Publication date: October 9, 2003Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson
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Patent number: 6616896Abstract: Apparatus or systems which employ luminescence quenching to produce a signal indicative of oxygen concentration. Components of such systems include: an airway adapter, sampling cell, or the like, having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical signal indicative of oxygen concentration in the gases being monitored; and subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector.Type: GrantFiled: April 24, 2001Date of Patent: September 9, 2003Assignee: NTC Technology Inc.Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke
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Publication number: 20030047188Abstract: A face mask including a gas monitoring capability for improved patient management in combination with improved efficiency of supplemental oxygen delivery to the patient is provided. The face mask of the present invention is configured to direct substantially all of the inspiratory and expiratory gas streams to and from the patient through a gas measuring device and to efficiently deliver supplemental oxygen. As such, the face mask permits measurement of both oral and nasal gas exchange.Type: ApplicationFiled: August 29, 2002Publication date: March 13, 2003Applicant: Respironics, Inc.Inventors: Leslie E. Mace, David Rich, Randall J. Terry, John A. Triunfo, Anthony T. Pierry, Michael J.R. Polson
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Publication number: 20020098120Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal.Type: ApplicationFiled: January 24, 2001Publication date: July 25, 2002Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson
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Publication number: 20020029003Abstract: An integrated airway adapter capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.Type: ApplicationFiled: April 24, 2001Publication date: March 7, 2002Inventors: Leslie E. Mace, Lawrence L. Labuda, Perry R. Blazewicz, David R. Rich, Michael B. Jaffe, Joseph A. Orr, Scott A. Kofoed
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Patent number: 6325978Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.Type: GrantFiled: August 4, 1998Date of Patent: December 4, 2001Assignee: NTC Technology Inc.Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke
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Publication number: 20010031224Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.Type: ApplicationFiled: April 24, 2001Publication date: October 18, 2001Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke