Patents by Inventor Leslie E Mace

Leslie E Mace has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11538569
    Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: December 27, 2022
    Assignee: Freespira. Inc.
    Inventors: Leslie E. Mace, Elizabeth K. Siegelman, Debra L. Reisenthel, Simon W. H. Thomas
  • Publication number: 20220270739
    Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.
    Type: Application
    Filed: May 11, 2022
    Publication date: August 25, 2022
    Inventors: Leslie E. MACE, Elizabeth K. SIEGELMAN, Debra L. REISENTHEL, Simon W.H. THOMAS
  • Patent number: 10175254
    Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.
    Type: Grant
    Filed: July 16, 2014
    Date of Patent: January 8, 2019
    Assignee: PALO ALTO HEALTH SCIENCES, INC.
    Inventors: Leslie E. Mace, Elizabeth K. Siegelman, Debra L. Reisenthel, Simon W. H. Thomas
  • Publication number: 20180335440
    Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.
    Type: Application
    Filed: July 31, 2018
    Publication date: November 22, 2018
    Inventors: Leslie E. MACE, Elizabeth K. SIEGELMAN, Debra L. REISENTHEL, Simon W.H. THOMAS
  • Publication number: 20160245830
    Abstract: Quantitative colorimetric carbon dioxide detection and measurement systems are disclosed. The systems can include a gas conduit, a colorimetric indicator adapted to exhibit a color change in response to exposure to carbon dioxide gas, a temperature controller operatively coupled to the colorimetric indicator and configured to control the temperature of the colorimetric indicator, an electro-optical sensor assembly including a light source or sources adapted to transmit light to the colorimetric indicator, and a photodiode or photodiodes configured to detect light reflected from the colorimetric indicator and to generate a measurement signal, and a processor in communication with the electro-optical sensor assembly. The processor can be configured to receive the measurement signal generated by the electro-optical sensor assembly and to compute a concentration of carbon dioxide based on the measurement signal.
    Type: Application
    Filed: July 16, 2014
    Publication date: August 25, 2016
    Inventors: Leslie E. MACE, Elizabeth K. SIEGELMAN, Debra L. REISENTHEL, Simon W.H. THOMAS
  • Patent number: 7897109
    Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical-signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: March 1, 2011
    Assignee: RIC Investments, LLC
    Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke
  • Patent number: 7833480
    Abstract: Apparatus or systems which employ luminescence-quenching to produce a signal indicative of oxygen concentration.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: November 16, 2010
    Assignee: RIC Investments, Inc.
    Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson
  • Publication number: 20100036272
    Abstract: A system (300) for measuring a metabolic parameter. The system includes an integrated airway adapter (20, 100, 200) capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.
    Type: Application
    Filed: January 31, 2008
    Publication date: February 11, 2010
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Leslie E. Mace, Joseph A. Orr, David R. Rich, Michael B. Jaffe, Jason Alderete
  • Patent number: 7335164
    Abstract: An integrated airway adapter capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: February 26, 2008
    Assignee: NTC Technology, Inc.
    Inventors: Leslie E. Mace, Lawrence L. Labuda, Perry R. Blazewicz, David R. Rich, Michael B. Jaffe, Joseph A. Orr, Scott A. Kofoed
  • Patent number: 7004168
    Abstract: A face mask including a gas monitoring capability for improved patient management in combination with improved efficiency of supplemental oxygen delivery to the patient is provided. The face mask of the present invention is configured to direct substantially all of the inspiratory and expiratory gas streams to and from the patient through a gas measuring device and to efficiently deliver supplemental oxygen. As such, the face mask permits measurement of both oral and nasal gas exchange.
    Type: Grant
    Filed: August 29, 2002
    Date of Patent: February 28, 2006
    Assignee: Respironics, Inc.
    Inventors: Leslie E Mace, David R Rich, Randall J Terry, John A Triunfo, Jr., Anthony T Pierry, Michael J. R. Polson
  • Patent number: 6815211
    Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.
    Type: Grant
    Filed: August 4, 1998
    Date of Patent: November 9, 2004
    Assignee: NTC Technology
    Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Gamal-Eddin Khalil
  • Publication number: 20040013570
    Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical-signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.
    Type: Application
    Filed: April 24, 2001
    Publication date: January 22, 2004
    Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke
  • Patent number: 6632402
    Abstract: Apparatus or systems which employ luminescence-quenching to produce a signal indicative of oxygen concentration.
    Type: Grant
    Filed: January 24, 2001
    Date of Patent: October 14, 2003
    Assignee: NTC Technology Inc.
    Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson
  • Publication number: 20030190262
    Abstract: Apparatus or systems which employ luminescence-quenching to produce a signal indicative of oxygen concentration.
    Type: Application
    Filed: March 28, 2003
    Publication date: October 9, 2003
    Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson
  • Patent number: 6616896
    Abstract: Apparatus or systems which employ luminescence quenching to produce a signal indicative of oxygen concentration. Components of such systems include: an airway adapter, sampling cell, or the like, having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical signal indicative of oxygen concentration in the gases being monitored; and subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: September 9, 2003
    Assignee: NTC Technology Inc.
    Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke
  • Publication number: 20030047188
    Abstract: A face mask including a gas monitoring capability for improved patient management in combination with improved efficiency of supplemental oxygen delivery to the patient is provided. The face mask of the present invention is configured to direct substantially all of the inspiratory and expiratory gas streams to and from the patient through a gas measuring device and to efficiently deliver supplemental oxygen. As such, the face mask permits measurement of both oral and nasal gas exchange.
    Type: Application
    Filed: August 29, 2002
    Publication date: March 13, 2003
    Applicant: Respironics, Inc.
    Inventors: Leslie E. Mace, David Rich, Randall J. Terry, John A. Triunfo, Anthony T. Pierry, Michael J.R. Polson
  • Publication number: 20020098120
    Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal.
    Type: Application
    Filed: January 24, 2001
    Publication date: July 25, 2002
    Inventors: Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson
  • Publication number: 20020029003
    Abstract: An integrated airway adapter capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.
    Type: Application
    Filed: April 24, 2001
    Publication date: March 7, 2002
    Inventors: Leslie E. Mace, Lawrence L. Labuda, Perry R. Blazewicz, David R. Rich, Michael B. Jaffe, Joseph A. Orr, Scott A. Kofoed
  • Patent number: 6325978
    Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.
    Type: Grant
    Filed: August 4, 1998
    Date of Patent: December 4, 2001
    Assignee: NTC Technology Inc.
    Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke
  • Publication number: 20010031224
    Abstract: Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminescence decaying in a manner reflecting the concentration of oxygen in gases flowing through the airway adapter or other flow device; (2) a transducer which has a light source for exciting a luminescable composition in the sensor into luminescence and a light sensitive detector for converting energy emitted from the luminescing composition as that composition is quenched into an electrical signal indicative of oxygen concentration in the gases being monitored; and (3) subsystems for maintaining the sensor temperature constant and for processing the signal generated by the light sensitive detector. Sensors for systems of the character just described, methods of fabricating those sensors, and methods for installing the sensors in the flow device.
    Type: Application
    Filed: April 24, 2001
    Publication date: October 18, 2001
    Inventors: Lawrence L. Labuda, Perry R. Blazewicz, Leslie E. Mace, Jerry R. Apperson, Walter A. Cooke