Patents by Inventor Leslie H. DeRiemer Anderson

Leslie H. DeRiemer Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhancement of hybridization of nucleic acids by anionic polymers
    Patent number: 4689294
    Abstract: The rate of hybridization between two complementary polynucleotide segments in an aqueous medium is increased by the presence of the anionic polymers polyacrylate and polymethacrylate. The acceleration effect is particularly useful in nucleic acid hybridization assays involving immobilization of sample nucleic acids and the use of labeled probes. Nonspecific binding of probe to nitrocellulose supports is substantially lower in the presence of the present polymers than in the presence of the prior art accelerator dextran sulfate. Polyacrylate is particularly advantageous since it has been found to be effective at low concentrations and is significantly less expensive than the prior art compound.
    Type: Grant
    Filed: November 19, 1984
    Date of Patent: August 25, 1987
    Assignee: Miles Laboratories, Inc.
    Inventors: Sophie J. Boguslawski, Leslie H. DeRiemer Anderson