Patents by Inventor Leslie H. Hamilton

Leslie H. Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11786153
    Abstract: A wearable sensor system includes a flexible patch, an electronic circuit disposed on the flexible patch, and a disposable sensor disposed on the flexible patch and connected to the electronic circuit via a socket. The disposable sensor detects a chemical compound. The electronic circuit generates a detection signal commensurate with the chemical compound detected by the disposable sensor. The disposable sensor is removably plugged into the socket, thereby permitting replacement of the disposable sensor upon satisfaction of a predetermined condition. A battery disposed is on the flexible patch and connected to the electronic circuit to power the electronic circuit. A transceiver is connected to the electronic circuit, wherein the transceiver transmits the detection signal.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: October 17, 2023
    Assignee: The Johns Hopkins University
    Inventors: Konstantinos Gerasopoulos, Julia B. Patrone, Leslie H. Hamilton, Luke J. Currano, Matthew A. Hagedon, Felix Connor Sage, Mekbib Astatke
  • Publication number: 20210219895
    Abstract: A muscle activity sensor includes a base textile, an electrode, and an interconnect. The base textile is configured to apply a compression force against a dermal surface of the user. The electrode is coupled to the base textile and includes a sensor layer including a conductive textile coupled to a dermal side of the base textile. The sensor layer is configured to receive electrical signals associated with muscle activity of the user. The electrode may also be configured to provide the electrical signals as an output signal. The interconnect may be coupled to the base textile over a distance from the electrode to an interconnect junction contact such that the interconnect moves with the base textile as the user moves. The interconnect may be further configured to deliver the output signal from the electrode to the interconnect junction contact.
    Type: Application
    Filed: November 10, 2020
    Publication date: July 22, 2021
    Inventors: Luke J. Currano, Korine A. Ohiri, Leslie H. Hamilton, Matthew T. McGuire, Paul J. Biermann, Leah M. Strohsnitter
  • Publication number: 20200138343
    Abstract: A wearable sensor system includes a flexible patch, an electronic circuit disposed on the flexible patch, and a disposable sensor disposed on the flexible patch and connected to the electronic circuit via a socket. The disposable sensor detects a chemical compound. The electronic circuit generates a detection signal commensurate with the chemical compound detected by the disposable sensor. The disposable sensor is removably plugged into the socket, thereby permitting replacement of the disposable sensor upon satisfaction of a predetermined condition. A battery disposed is on the flexible patch and connected to the electronic circuit to power the electronic circuit. A transceiver is connected to the electronic circuit, wherein the transceiver transmits the detection signal.
    Type: Application
    Filed: August 30, 2019
    Publication date: May 7, 2020
    Inventors: Konstantinos Gerasopoulos, Julia B. Patrone, Leslie H. Hamilton, Luke J. Currano, Matthew A. Hagedon, Felix Connor Sage, Mekbib Astatke
  • Patent number: 10344320
    Abstract: A capacitive liquid crystal (LC) biosensor for sensing a target biological agent includes a support board; a flow channel on the support board, the flow channel having an inlet port at a first end and an exit port at a second end; at least two electrodes, the at least two electrodes including a first electrode on a flow channel first surface and a second electrode on a flow channel second surface opposite the flow channel first surface; an electricity source connected to the first electrode and the second electrode; and an LC sensor array positioned within the flow channel. An LC sensor array includes a sensor support surface; wells positioned on the sensor support surface; an organic LC phase within each of the plurality of wells; and an aqueous phase having an analyte positioned above the organic LC phase within the wells.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: July 9, 2019
    Assignee: The Johns Hopkins University
    Inventors: Emily P. English, David B. Taubenheim, Christopher E. Bradburne, Matthew P. Yeager, Jason E. Tiffany, Leslie H. Hamilton
  • Publication number: 20190201578
    Abstract: A biomaterial implant may include a collagen membrane. The biomaterial implant may further include a plurality of nanoparticles embedded in the collagen membrane. Furthermore, at least one nanoparticle of the plurality of nanoparticles may include a polymer shell and a bio-active therapeutic agent encapsulated by the polymer shell.
    Type: Application
    Filed: October 26, 2018
    Publication date: July 4, 2019
    Inventors: Morgana M. Trexler, Xiomara Calderon-Colon, Leslie H. Hamilton, Min Zhao, Brian Reid, Julia B. Patrone, Lance M. Baird
  • Publication number: 20190183807
    Abstract: A therapeutic agent release system may be provided. The therapeutic agent release system may include a plurality of polymer shells having a diameter of about 50-200 nanometers. The therapeutic agent release system may further include a bio-active therapeutic agent encapsulated by each of the polymer shells and being configured to heal an injury and increase a wound electric signal of the injury thereby increasing a healing rate of the injury. Each of the polymer shells may have a degradation profile configured to control a release of the bio-active therapeutic agent through the polymer shell to the injury over a predetermined period of time.
    Type: Application
    Filed: October 19, 2018
    Publication date: June 20, 2019
    Inventors: Lance M. Baird, Xiomara Calderon-Colon, Morgana M. Trexler, Leslie H. Hamilton
  • Publication number: 20160327506
    Abstract: A capacitive liquid crystal (LC) biosensor for sensing a target biological agent includes a support board; a flow channel on the support board, the flow channel having an inlet port at a first end and an exit port at a second end; at least two electrodes, the at least two electrodes including a first electrode on a flow channel first surface and a second electrode on a flow channel second surface opposite the flow channel first surface; an electricity source connected to the first electrode and the second electrode; and an LC sensor array positioned within the flow channel. An LC sensor array includes a sensor support surface; wells positioned on the sensor support surface; an organic LC phase within each of the plurality of wells; and an aqueous phase having an analyte positioned above the organic LC phase within the wells.
    Type: Application
    Filed: May 5, 2016
    Publication date: November 10, 2016
    Inventors: Emily P. English, David B. Taubenheim, Christopher E. Bradburne, Matthew P. Yeager, Jason E. Tiffany, Leslie H. Hamilton