Patents by Inventor Leslie J. A. Jennings

Leslie J. A. Jennings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral purine derivatives with improved gastrointestinal absorption
    Patent number: 5252575
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein R.sub.1 is hydrogen or hydroxy; andR.sub.2 is C.sub.1-6 alkyl;which are pro-drugs for 9-(3-hydroxyprop-1-oxy)guanine having antiviral activity, a process for their preparation and their use as pharmaceuticals.
    Type: Grant
    Filed: May 21, 1992
    Date of Patent: October 12, 1993
    Assignee: Beecham Group p.l.c.
    Inventors: Michael R. Harnden, Paul G. Wyatt, Leslie J. A. Jennings
  • Antiviral purine derivatives
    Patent number: 5108994
    Abstract: Compounds of formula (I), and pharmaceutically acceptable salts thereof: ##STR1## wherein R.sub.1 is hydroxy or amino;R.sub.2 is hydrogen or amino;R.sub.3 is hydrogen, hydroxymethyl or acyloxymethyl;R.sub.4 is a group of formula: ##STR2## wherein R.sub.5 and R.sub.6 are independently selected from hydrogen, C.sub.1-6 alkyl and optionally substituted phenyl; orR.sub.3 and R.sub.4 together are: ##STR3## wherein R.sub.6 is as defined above;having antiviral activity, processes for their preparation and their pharmaceutical use.
    Type: Grant
    Filed: May 23, 1990
    Date of Patent: April 28, 1992
    Assignee: Beecham Group p.l.c.
    Inventors: Michael R. Harnden, Leslie J. A. Jennings