Patents by Inventor Leslie Karen WILLIAMS

Leslie Karen WILLIAMS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amylase inhibitor compounds, methods of their use and compositions thereof
    Patent number: 11608353
    Abstract: There are provided compounds of Formula I: various compositions thereof and methods for their use in the inhibition of ?-amylase.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: March 21, 2023
    Assignee: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Stephen G. Withers, Gary D. Brayer, Leslie Karen Williams, Xiaohua Zhang
  • AMYLASE INHIBITOR COMPOUNDS, METHODS OF THEIR USE AND COMPOSITIONS THEREOF
    Publication number: 20200079810
    Abstract: There are provided compounds of Formula I: various compositions thereof and methods for their use in the inhibition of ?-amylase.
    Type: Application
    Filed: November 6, 2019
    Publication date: March 12, 2020
    Inventors: STEPHEN G. WITHERS, GARY D. BRAYER, LESLIE KAREN WILLIAMS, XIAOHUA ZHANG
  • Mammalian glucosidase inhibitors, methods for their use and pharmaceutical compositions thereof
    Patent number: 10583167
    Abstract: Provided are methods, uses and pharmaceutical compositions for inhibition of mammalian alpha-amylase in a subject, with a Helianthamide peptide or a derivative thereof in a biologically effective amount. The subject in need of alpha-amylase inhibition, may have or be at risk of developing one or more of the following: Middleton syndrome; a motility disorder of the gastrointestinal tract; postprandial reactive hypoglycemia; postprandial syndrome; irritable bowel syndrome; diabetes mellitus type 1; diabetes mellitus type 2; pre-diabetes; obesity, dumping syndrome; infant dumping syndrome; polycystic ovary syndrome; steatohepatitis; and viral infection.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: March 10, 2020
    Assignee: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Stephen G. Withers, Andrew Tarling, Raymond J. Andersen, Gary D. Brayer, Robert Keyzers, Christina Rose Tysoe, Leslie Karen Williams
  • MAMMALIAN GLUCOSIDASE INHIBITORS, METHODS FOR THEIR USE AND PHARMACEUTICAL COMPOSITIONS THEREOF
    Publication number: 20180193413
    Abstract: Provided are methods, uses and pharmaceutical compositions for inhibition of mammalian alpha-amylase in a subject, with a Helianthamide peptide or a derivative thereof in a biologically effective amount. The subject in need of alpha-amylase inhibition, may have or be at risk of developing one or more of the following: Middleton syndrome; a motility disorder of the gastrointestinal tract; postprandial reactive hypoglycemia; postprandial syndrome; irritable bowel syndrome; diabetes mellitus type 1; diabetes mellitus type 2; pre-diabetes; obesity, dumping syndrome; infant dumping syndrome; polycystic ovary syndrome; steatohepatitis; and viral infection.
    Type: Application
    Filed: June 29, 2016
    Publication date: July 12, 2018
    Inventors: Stephen G. WITHERS, Andrew TARLING, Raymond J. ANDERSEN, Gary D. BRAYER, Robert KEYZERS, Christina Rose TYSOE, Leslie Karen WILLIAMS