Patents by Inventor Leslie Nangle Greene

Leslie Nangle Greene has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS COMPRISING ANTI-NRP2 ANTIBODIES
    Publication number: 20230312730
    Abstract: Provided are antibodies and antigen-binding fragments thereof that specifically bind to human neuropilin-2 (NRP2) polypeptides, including those that modulate binding interactions between human NRP2 and at least one NRP2 ligand, for example, human histidyl-tRNA synthetase (HRS), and which thereby modulate subsequent NRP2-mediated downstream signaling events, including related therapeutic compositions and methods for modulating NRP2 activity and treating diseases such as NRP2-associated diseases.
    Type: Application
    Filed: October 20, 2022
    Publication date: October 5, 2023
    Inventors: Luke G. BURMAN, Yee Ting (Esther) CHONG, Yanyan GENG, Leslie Nangle GREENE, Kristina HAMEL, David KING, Ann MENEFEE, Kaitlyn RAUCH, Zhiwen XU, Liting ZHAI
  • Compositions and methods comprising anti-NRP2 antibodies
    Patent number: 11505610
    Abstract: Provided are antibodies and antigen-binding fragments thereof that specifically bind to human neuropilin-2 (NRP2) polypeptides, including those that modulate binding interactions between human NRP2 and at least one NRP2 ligand, for example, human histidyl-tRNA synthetase (HRS), and which thereby modulate subsequent NRP2-mediated downstream signaling events, including related therapeutic compositions and methods for modulating NRP2 activity and treating diseases such as NRP2-associated diseases.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: November 22, 2022
    Assignee: aTyr Pharma, Inc.
    Inventors: Luke Burman, Yee Ting (Esther) Chong, Yanyan Geng, Leslie Nangle Greene, Kristina Hamel, David King, Ann Menefee, Kaitlyn Rauch, Zhiwen Xu, Liting Zhai
  • COMPOSITIONS AND METHODS COMPRISING ANTI-NRP2 ANTIBODIES
    Publication number: 20190309076
    Abstract: Provided are antibodies and antigen-binding fragments thereof that specifically bind to human neuropilin-2 (NRP2) polypeptides, including those that modulate binding interactions between human NRP2 and at least one NRP2 ligand, for example, human histidyl-tRNA synthetase (HRS), and which thereby modulate subsequent NRP2-mediated downstream signaling events, including related therapeutic compositions and methods for modulating NRP2 activity and treating diseases such as NRP2-associated diseases
    Type: Application
    Filed: April 5, 2019
    Publication date: October 10, 2019
    Inventors: Luke BURMAN, Yee Ting (Esther) CHONG, Yanyan GENG, Leslie Nangle GREENE, Kristina HAMEL, David KING, Ann MENEFEE, Kaitlyn RAUCH, Zhiwen XU, Liting ZHAI
  • ANTI-HRS ANTIBODIES AND COMBINATON THERAPIES FOR TREATING CANCERS
    Publication number: 20180282402
    Abstract: Provided are antibodies that specifically bind to human histidyl-tRNA synthetase and related therapeutic compositions and methods for treating cancer, including as standalone therapies or in combination with cancer immunotherapies, for example, immune checkpoint modulators such as PD-1 inhibitors.
    Type: Application
    Filed: November 30, 2017
    Publication date: October 4, 2018
    Inventors: Ryan Andrew Adams, Luke Burman, Yeeting Chong, David King, John D. Mendlein, Leslie Nangle Greene, Kathleen Ogilvie, Kaitlyn Rauch