Patents by Inventor Leslie Oppenheimer

Leslie Oppenheimer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Two step process for coating of antibodies to a solid phase
    Patent number: 5399500
    Abstract: A process for coating an antibody on a substrate includes two steps. A secondary antibody to a primary antibody is coated on the substrate followed by a coating with primary antibody in the presence of blocking and stabilizer agents.
    Type: Grant
    Filed: June 26, 1992
    Date of Patent: March 21, 1995
    Assignee: Becton Dickinson and Company
    Inventors: Leslie Oppenheimer, Lewis R. Pollack
  • Surface modified liposomes
    Patent number: 5248590
    Abstract: A liposome reagent encapsulating a molecule to be targeted to a body site or used as an assay reporter has a ligand and a sulfonate-containing group on the liposome surface. Preferred ligands are antibodies or antibody fragments and preferred encapsulants are enzymes or dyes. In the most preferred reagents, the antibody and sulfonate-containing group are covalently bonded to the liposome surface through a connecting group which includes a succinimidyl group resulting from addition of the ligand or sulfonate-containing group to a maleimidyl group. The invention includes a kit of materials for performing an assay using the reagent of the invention as the tracer.
    Type: Grant
    Filed: July 22, 1991
    Date of Patent: September 28, 1993
    Assignee: Becton, Dickinson and Company
    Inventors: Herman Rutner, Josephine D. Readio, Leslie Oppenheimer