Abstract: Systems and methods for implementing a biomedical innovations datametrics dashboard are presented. The dashboard can utilize data from real-world data sources to inform a simulation model which performs simulations of the biomedical innovation pipeline and related entities and processes. The dashboard can utilize the simulation model as well as feedback solicited from a user to assist in performing multi-objective optimization according to the user's preferences. The dashboard can help policy decision-makers and other stakeholders decide on a combination of policies that best incentivizes private sector biomedical innovation in order to achieve a satisfactory set of outcomes, which may include, but is not limited to, reductions in DALYs, healthcare costs, increases in industry NPV, and improved clinical trial quality.

Abstract: Systems and methods for implementing a biomedical innovations datametrics dashboard are presented. The dashboard can utilize data from real-world data sources to inform a simulation model which performs simulations of the biomedical innovation pipeline and related entities and processes. The dashboard can utilize the simulation model as well as feedback solicited from a user to assist in performing multi-objective optimization according to the user's preferences. The dashboard can help policy decision-makers and other stakeholders decide on a combination of policies that best incentivizes private sector biomedical innovation in order to achieve a satisfactory set of outcomes, which may include, but is not limited to, reductions in DALYs, healthcare costs, increases in industry NPV, and improved clinical trial quality.

Abstract: A funding method and system provides funding at all stages of product development and manufacture. One or more of the funding organizations are matched with one or more of the securities issuing entities, and one or more of the securities issuing entities are matched with one or more of the pathable development projects, based at least in part on projected financial return, a schedule of tranches for the stages of the pathable development project, and a surety arrangement. One or more of the securities purchasing entities are matched with one or more securities issuing entities.