Patents by Inventor Leslie R McMahon

Leslie R McMahon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant OPAA enzyme with increased catalytic efficiency on GP
    Patent number: 10363289
    Abstract: The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolase enzymes having three site mutations, methods of production, and methods of use to effectively degrade toxic organophosphorus compounds, most preferably GP (2, 2?-dimethylcyclopentyl methylphosphonofluoridate).
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: July 30, 2019
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventors: Steven P. Harvey, Mark A Guelta, Leslie R McMahon
  • Mutant OPAA enzyme with increased catalytic efficiency on organophosphorus compound GP
    Patent number: 10335465
    Abstract: The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolase enzymes having three site mutations, methods of production, and methods of use to effectively degrade toxic organophosphorus compounds, most preferably GP (2,2?-dimethylcyclopentyl methylphosphonofluoridate).
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: July 2, 2019
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventors: Steven P Harvey, Melissa M Dixon, Mark A Guelta, Leslie R McMahon
  • Mutant OPAA enzymes with increased catalytic efficiency on organophosphorus compound EA1356
    Patent number: 10124043
    Abstract: The invention comprises isolated, mutant, non-wild-type organophosphorus acid anhydrolase (OPAA) enzymes having three site mutations, methods of production, and methods of use to effectively degrade organophosphorus compound EA1356 (2-methylcyclohexyl methylphosphonofluoridate) with greater catalytic efficiency than the wild-type OPAA enzyme.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: November 13, 2018
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventors: Steven P Harvey, Mark A Guelta, Leslie R McMahon