Patents by Inventor Leslie Roy

Leslie Roy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240181024
    Abstract: A method of treating or preventing a respiratory infection can include delivering aerosolized droplets of an antiviral solution to lung tissue of a subject, the antiviral solution including an aqueous carrier and an ATH conjugate that is solubilized in the aqueous carrier. The ATH conjugate includes antithrombin covalently bonded to heparin, the heparin including a polysaccharide chain having from about 15 to about 1,500 monosaccharide units.
    Type: Application
    Filed: March 25, 2022
    Publication date: June 6, 2024
    Applicant: ATH Therapeutics Inc.
    Inventors: Leslie Roy BERRY, Anthony Kam Chuen CHAN, William JACKSON, Attilio DIFIORE
  • Publication number: 20240127716
    Abstract: The present disclosure provides an eye-imaging training apparatus including an actuator to articulate one or more movable eyeball members. The eye-imaging training apparatus provides a caregiver a training tool for practicing various eye-imaging techniques that simulate or mimic natural and animal-like eye movement. For example, the eye-imaging training apparatus may include an eyeball member that can move in multiple directions to simulate human-like eye movement. The eye-imaging training apparatus can train a caregiver to practice, for example, aligning an eye-imaging camera, calibrating the eye-imaging camera (e.g., determining the desired optical parameters), and retracting eyelids for eye-imaging. The present disclosure is also related to systems and methods for eye imaging using an eye-imaging training apparatus.
    Type: Application
    Filed: October 5, 2023
    Publication date: April 18, 2024
    Applicant: Phoenix-Micron, Inc.
    Inventors: Jonathan Roy Thorn, Jonathan Scott Carr, Leslie Mackeen
  • Patent number: 11752242
    Abstract: Medical devices, systems, and methods for treating conditions using antithrombin-heparin conjugates are disclosed. For example, medical devices can be coated with antithrombin-heparin (ATH) resulting in reduced thrombogenicity. Various conditions can likewise be treated with ATH.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: September 12, 2023
    Assignee: ATH Therapeutics Inc.
    Inventors: Attilio Difiore, Leslie Roy Berry, Anthony Kam Chuen Chan
  • Publication number: 20220004342
    Abstract: An embodiment of an electronic apparatus may include a substrate and a controller coupled to the substrate, the controller including circuitry to control access to a NAND-based storage media that includes a plurality of NAND devices located on the substrate and organized into two or more physical clusters with each NAND device uniquely assigned to one of the two or more physical clusters, perform data access to a first physical cluster of the two or more physical clusters at a first bandwidth, and perform data access to a second physical cluster of the two or more physical clusters at a second bandwidth that is slower than the first bandwidth. Other embodiments are disclosed and claimed.
    Type: Application
    Filed: September 22, 2021
    Publication date: January 6, 2022
    Applicant: Intel Corporation
    Inventors: Jorge Ulises Martinez Araiza, Michael Leslie Roy, Andrew Morning-Smith
  • Publication number: 20200261926
    Abstract: A spray head for an agricultural sprayer, the spray head including a fan with a central axis, the spray head also including dual liquid manifolds coaxial about the fan's central axis, each manifold having a plurality of spray nozzles positioned to be capable of spraying liquid into air exiting the fan, and each manifold having a liquid inlet and a liquid outlet so as to permit individual control of liquid through each manifold.
    Type: Application
    Filed: February 13, 2020
    Publication date: August 20, 2020
    Applicant: Croplands Equipment Pty Ltd
    Inventors: Leslie Roy Bollenhagen, Stephen Charles Norton, John Flint Packer
  • Publication number: 20200068869
    Abstract: A mobile agricultural spray apparatus, the spray apparatus including at least one spray nozzle arranged to be on one side of a crop during spraying and an overspray collector arranged to be on the opposite side of the crop during spraying such that the overspray collector can capture overspray from the spray nozzle during operation, wherein the overspray collector includes: at least two curtains, the curtains including at least one pervious and flexible front curtain and an impervious rear curtain; an overspray space between the pervious front curtain and the impervious rear curtain; and an overspray chamber in fluid communication with at least the overspray space for collection of overspray captured by the overspray collector.
    Type: Application
    Filed: June 29, 2017
    Publication date: March 5, 2020
    Applicant: Croplands Equipment Pty Ltd
    Inventors: Leslie Roy Bollenhagen, David Manktelow
  • Publication number: 20190030066
    Abstract: Compositions and methods for preventing thrombogenesis can include antithrombin and heparin. In one example, a conjugate of antithrombin and heparin where at least 50 wt % of the heparin is conjugated to antithrombin can be present. Furthermore, in one example, at least 98 wt % of the heparin in the composition has a molecular weight greater than 3,000 Daltons.
    Type: Application
    Filed: October 4, 2018
    Publication date: January 31, 2019
    Applicant: ATTWILL Medical Solutions, Inc.
    Inventors: Leslie Roy Berry, Attilio DiFiore, Anthony Kam Chuen Chan
  • Publication number: 20180177924
    Abstract: Medical devices, systems, and methods for treating conditions using antithrombin-heparin conjugates are disclosed. For example, medical devices can be coated with antithrombin-heparin (ATH) resulting in reduced thrombogenicity. Various conditions can likewise be treated with ATH.
    Type: Application
    Filed: June 10, 2016
    Publication date: June 28, 2018
    Applicant: ATTWILL Medical Solution Inc.
    Inventors: Attilio Difiore, Leslie Roy Berry, Anthony Kam Chuen Chan
  • Publication number: 20170020911
    Abstract: Compositions and methods for preventing thrombogenesis can include antithrombin and heparin. In one example, a conjugate of antithrombin and heparin where at least 50 wt % of the heparin is conjugated to antithrombin can be present. Furthermore, in one example, at least 98 wt % of the heparin in the composition has a molecular weight greater than 3,000 Daltons.
    Type: Application
    Filed: April 15, 2016
    Publication date: January 26, 2017
    Applicant: ATTWILL Medical Solutions Inc.
    Inventors: Leslie Roy Berry, Attilio DiFiore, Anthony Kam Chuen Chan
  • Patent number: 7524826
    Abstract: The present invention provides methods for preventing the generation of active thrombin on the surface of cells. The present methods are based upon the surprising discovery that expression or activation of an ER resident chaperone protein in a cell inhibits the generation of thrombin on the surface of the cell. Accordingly, expressing or activating an ER resident chaperone protein can be used to treat or prevent any of a number of thrombotic diseases.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: April 28, 2009
    Assignee: McMaster University and Hamilton Health Sciences Corporation
    Inventors: Richard C. Austin, Anthony K. C. Chan, Leslie Roy Berry
  • Publication number: 20090078394
    Abstract: A cooling system for a machine is disclosed. The cooling system may have a heat exchanger pivotal between a first position and a second position. In addition, the cooling system may also have a positioning mechanism configured to move the heat exchanger between the first and second positions and retain the heat exchanger in at least one of the first and second positions.
    Type: Application
    Filed: April 16, 2008
    Publication date: March 26, 2009
    Inventor: Leslie Roy Weatherup
  • Patent number: 7045585
    Abstract: Novel conjugates of glycosaminoglycans, particularly heparin and dermatan sulfate, and amine containing species and therapeutic uses thereof are described. In particular, mild methods of conjugating heparins to proteins, such as antithrombin III and heparin cofactor II, which provide covalent conjugates which retain maximal biological activity are described. Uses of these conjugates to prevent thrombogenesis, in particular in lung airways, such as found in infant and adult respiratory distress syndrome, and on surfaces in contact with blood are also described.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: May 16, 2006
    Assignee: Hamilton Civic Hospital Research Development Inc.
    Inventors: Leslie Roy Berry, Hugh O'Brodovich, legal representative, Anthony Kam Chuen Chan, Maureen Andrew, deceased
  • Publication number: 20030124705
    Abstract: Novel conjugates of glycosaminoglycans, particularly heparin and dermatan sulfate, and amine containing species and therapeutic uses thereof are described. In particular, mild methods of conjugating heparins to proteins, such as antithrombin III and heparin cofactor II, which provide covalent conjugates which retain maximal biological activity are described. Uses of these conjugates to prevent thrombogenesis, in particular in lung airways, such as found in infant and adult respiratory distress syndrome, and on surfaces in contact with blood are also described.
    Type: Application
    Filed: March 20, 2002
    Publication date: July 3, 2003
    Inventors: Leslie Roy Berry, Maureen Andrew, Anthony Kam Chuen Chan
  • Patent number: 6372774
    Abstract: N-Phenylpyrazole derivatives of the formula: wherein R1 represents optionally halogenated alkyl; R2 represents halogen, cyano, nitro, cycloalkyl, alkenyl, thiocyanato, optionally alkyl substituted sulphamoyl, optionally alkyl substituted carbamoyl, alkoxycarbonyl, alkanoyl or optionally halogenated alkyl; and R3 represents a hydrogen atom or a group N″R′″ or a variety of other groupings. These compounds possess arthropodicidal, plant nematocidal, anthelmintic and anti-protozoal properties; their preparation, compositions containing them and their use are described.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: April 16, 2002
    Assignee: Rhone-Poulenc Agriculture Ltd.
    Inventors: Leslie Roy Hatton, Ian George Buntain, David William Hawkins, Edgar William Parnell, Christopher John Pearson, David Alan Roberts
  • Publication number: 20020039791
    Abstract: The present invention provides methods for preventing the generation of active thrombin on the surface of cells. The present methods are based upon the surprising discovery that expression or activation of an ER resident chaperone protein in a cell inhibits the generation of thrombin on the surface of the cell. Accordingly, expressing or activating an ER resident chaperone protein can be used to treat or prevent any of a number of thrombotic diseases.
    Type: Application
    Filed: April 12, 2001
    Publication date: April 4, 2002
    Inventors: Richard C. Austin, Anthony K.C. Chan, Leslie Roy Berry
  • Patent number: 5916618
    Abstract: N-Phenylpyrazole derivatives of the formula: ##STR1## wherein R.sup.1 represents cyano, nitro, halogen, acetyl or formyl; R.sup.2 represents R.sup.5 SO.sub.2, R.sup.5 SO or R.sup.5 S in which R.sup.5 is optionally halogen substituted alkyl, alkenyl or alkynyl;R.sup.3 represents a hydrogen atom or a group NR.sup.6 R.sup.7 wherein R.sup.6 and R.sup.7 each represent hydrogen, alkyl, alkenylalkyl, alkynylalkyl, formyl, optionally halogen substituted alkanoyl, optionally halogen substituted alkoxycarbonyl, or alkoxymethyleneamino, halogen, or R.sup.6 and R.sup.7 together form a cyclic imide and R.sup.4 represents a substituted phenyl group possess arthropodicidal, plant nematocidal, anthelmintic and anti-protozoal properties; their preparation, compositions containing them and their use are described.
    Type: Grant
    Filed: October 7, 1997
    Date of Patent: June 29, 1999
    Assignee: Rhone-Poulenc Agriculture Ltd.
    Inventors: Leslie Roy Hatton, Ian George Buntain, David William Hawkins, Edgar William Parnell, Christopher John Pearson, David Alan Roberts
  • Patent number: 5829245
    Abstract: A gas turbine that has turbine vanes that can be cooled with either steam or air includes a compressor that compresses air, a combustor enclosed within a shell and in flow communication with the compressor, a turbine in flow communication with the combustor and receiving hot gas from the combustor and turbine vanes. The turbine vanes having an airfoil, a shroud and a cooling circuit that cools the airfoil and the shrouds with either steam or air.
    Type: Grant
    Filed: December 31, 1996
    Date of Patent: November 3, 1998
    Assignee: Westinghouse Electric Corporation
    Inventors: Gerard McQuiggan, Raymond Scott Nordlund, Leslie Roy Southall, William Edward North, Zachary Sinnott
  • Patent number: 5714191
    Abstract: N-Phenylpyrazole derivatives of the formula: ##STR1## wherein R.sup.1 represents cyano, nitro, halogen, acetyl or formyl; R.sup.2 represents R.sup.5 SO.sub.2, R.sup.5 SO or R.sup.5 S in which R.sup.5 is optionally halogen substituted alkyl, alkenyl or alkynyl;R.sup.3 represents a hydrogen atom or a group NR.sup.6 R.sup.7 wherein R.sup.6 and R.sup.7 each represent hydrogen, alkyl, alkenylalkyl, alkynylalkyl, formyl, optionally halogen substituted alkanoyl, optionally halogen substituted alkoxycarbonyl, or alkoxymethyleneamino, halogen, or R.sup.6 and R.sup.7 together form a cyclic imide and R.sup.4 represents a substituted phenyl group possess arthropodicidal, plant nematocidal, anthelmintic and anti-protozoal properties; their preparation, compositions containing them and their use are described.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: February 3, 1998
    Assignee: Rhone-Poulenc Agriculture Ltd.
    Inventors: Leslie Roy Hatton, Ian George Buntain, David William Hawkins, Edgar William Parnell, Christopher John Pearson, David Alan Roberts
  • Patent number: 5642011
    Abstract: A support structure for clamping the inner coils and inner lamination rings of an inner stator column of an electromagnetic induction pump to prevent damaging vibration. A spine assembly, including a base plate, a center post and a plurality of ribs, serves as the structural frame for the inner stator. Stacked alignment rings provide structure to the lamination rings and locate them concentrically around the spine assembly central axis. The alignment rings are made of a material having a high thermal expansion coefficient to compensate for the lower expansion of the lamination rings and, overall, provide an approximate match to the expansion of the inner flow duct. The net result is that the radial clamping provided by the duct around the stator iron is maintained (approximately) over a range of temperatures and operating conditions.
    Type: Grant
    Filed: November 4, 1994
    Date of Patent: June 24, 1997
    Assignee: General Electric Company
    Inventors: Alan Wayne Fanning, Eugene Ellsworth Olich, Leslie Roy Dahl, Mahadeo Ratilal Patel
  • Patent number: PP27957
    Abstract: A new hop plant named ‘ADHA 483’ is disclosed. The cones of ‘ADHA 483’ mature in mid to late September in Moxee, Wash., and yield a crop of 2200 to 2300 pounds per acre. ‘ADHA 483’ is used for its semi-dwarf size and aromatic quality.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: May 2, 2017
    Assignee: AMERICAN DWARF HOP ASSOCIATION, LLC
    Inventors: Leslie Roy, Gary Morford