Patents by Inventor Leslie Wilson
Leslie Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230341313Abstract: Aspects of the present disclosure include a graphical user interface for processing flow cytometer data, such as for group-wise analysis of the flow cytometer data. The graphical user interface according to certain embodiments includes a first pane configured to display one or more compound populations having events generated from flow cytometry data of one or more samples comprising particles irradiated by a light source in a flow stream, a second pane configured to display data gates applied to each of the compound populations and a third pane configured to display data files for each of the irradiated samples used to generate the compound populations. Systems having an input module for receiving flow cytometer data and processor with memory having instructions for displaying and implementing commands from the graphical user interface are described. Non-transitory computer readable storage medium and methods for using the graphical user interface are also provided.Type: ApplicationFiled: January 18, 2023Publication date: October 26, 2023Inventors: Leslie Wilson, Richard Halpert
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Publication number: 20230304915Abstract: Aspects of the present disclosure include methods for processing cytometer data, such as for group-wise analysis of the cytometer data (e.g., flow cytometry data in FCS format, mass cytometry data, genomic cytometry data). Methods according to certain embodiments include generating a compound population of events that include data accessors from cytometry data, such as where the compound population of cytometer data is from two or more different samples retained as separate raw data files (e.g., are not concatenated to form a single combined data file). Systems having an input module for receiving cytometer data and processor with memory having instructions for practicing the subject methods are also described. Non-transitory computer readable storage medium is also provided.Type: ApplicationFiled: February 6, 2023Publication date: September 28, 2023Inventors: Richard Halpert, John Quinn, Michael Golden, Matthew Swindle, Clayton Ross Simons, Leslie Wilson
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Patent number: 11214397Abstract: The present disclosure relates to a method, apparatus and product in the art of reclosable packaging wherein the zipper is sealed to a film structure prior to treatment by the packaging machine for producing a thermoformed package. The zipper can be oriented in the machine direction, the transverse direction or at an angled orientation.Type: GrantFiled: March 3, 2014Date of Patent: January 4, 2022Assignee: ILLINOIS TOOL WORKS INC.Inventors: Leslie Wilson, W. Brandt Nako
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Publication number: 20190083069Abstract: A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. The sampling element can include an indicator strip for determining whether the amount of liquid sample sufficient for carrying out an assay.Type: ApplicationFiled: September 14, 2018Publication date: March 21, 2019Applicant: EXPRESS DIAGNOSTICS INT'L, INC.Inventors: Matthias W. Engel, Leslie Wilson, Paul Johnson
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Patent number: 10076314Abstract: A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. The sampling element can include an indicator strip for determining whether the amount of liquid sample sufficient for carrying out an assay.Type: GrantFiled: October 11, 2016Date of Patent: September 18, 2018Assignee: Express Diagnostics Int'l, Inc.Inventors: Matthias W. Engel, Leslie Wilson, Paul Johnson
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Publication number: 20180008240Abstract: A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. The sampling element can include an indicator strip for determining whether the amount of liquid sample sufficient for carrying out an assay.Type: ApplicationFiled: October 11, 2016Publication date: January 11, 2018Applicant: Express Diagnostics Int'l, Inc.Inventors: Matthias W. Engel, Leslie Wilson, Paul Johnson
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Patent number: 9462998Abstract: A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. The sampling element can include an indicator strip for determining whether the amount of liquid sample sufficient for carrying out an assay.Type: GrantFiled: September 24, 2012Date of Patent: October 11, 2016Assignee: EXPRESS DIAGNOSTICS INT'L, INC.Inventors: Matthias W. Engel, Leslie Wilson, Paul Johnson
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Patent number: 9414813Abstract: A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. The sampling element can include an indicator strip for determining whether the amount of liquid sample sufficient for carrying out an assay.Type: GrantFiled: September 29, 2014Date of Patent: August 16, 2016Assignee: EXPRESS DIAGNOSTICS INT'L, INC.Inventors: Matthias W. Engel, Leslie Wilson, Paul Johnson
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Publication number: 20160143971Abstract: Methods for using botanical compositions comprising administration of non-alcoholic organic extracts of Ganoderma lucidum, Salvia miltiorrhiza, and Scutellaria barbata in conjunction with docetaxel for cancer therapy, are provided. Method for treatment or therapy of prostate cancer in a human is provided, the method comprising: administering an effective amount of the botanical composition during a period of administering concurrently an effective amount of docetaxel, wherein the concurrent administration of the docetaxel and the botanical composition achieves a therapeutic effect that is more effective than either agent alone.Type: ApplicationFiled: June 3, 2014Publication date: May 26, 2016Inventors: James DAO, Jeffery DAO, William GERWICK, Lena GERWICK, MaryAnn JORDAN, Leslie WILSON
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Publication number: 20150173724Abstract: A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. The sampling element can include an indicator strip for determining whether the amount of liquid sample sufficient for carrying out an assay.Type: ApplicationFiled: September 29, 2014Publication date: June 25, 2015Inventors: Matthias W. ENGEL, Leslie WILSON, Paul JOHNSON
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Publication number: 20140315702Abstract: The present disclosure relates to a method, apparatus and product in the art of reclosable packaging wherein the zipper is sealed to a film structure prior to treatment by the packaging machine for producing a thermoformed package. The zipper can be oriented in the machine direction, the transverse direction or at an angled orientation.Type: ApplicationFiled: March 3, 2014Publication date: October 23, 2014Applicant: ILLINOIS TOOL WORKS INC.Inventors: Leslie WILSON, W. Brandt NAKO
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Publication number: 20130101616Abstract: Methods and compositions for prevention and therapy of cancer are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of Ganoderma lucidum, an extract of Salvia miltiorrhiza and an extract of Scutellaria barbata and optionally a therapeutically effective amount of an extract of Hippophae rhamnoides are provided. Novel synergistic effects of the use of these compounds in combination therapy are disclosed. Embodiments further comprising therapeutically effective amounts of at least one chemotherapeutic agent are also provided.Type: ApplicationFiled: April 12, 2012Publication date: April 25, 2013Inventors: James DAO, Tom C.S. DAO, David D. TONG, Leslie WILSON, Mary Ann JORDAN, William GERWICK
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Patent number: 8173177Abstract: Methods and compositions for prevention and therapy of cancer are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of Ganoderma lucidum, an extract of Salvia miltiorrhiza and an extract of Scutellaria barbata and optionally a therapeutically effective amount of an extract of Hippophae rhamnoides are provided. Novel synergistic effects of the use of these compounds in combination therapy are disclosed. Embodiments further comprising therapeutically effective amounts of at least one chemotherapeutic agent are also provided.Type: GrantFiled: September 8, 2004Date of Patent: May 8, 2012Assignee: Genyous Biomed International Inc.Inventors: James Dao, Tom C. S. Dao, David D. Tong, Leslie Wilson, Mary Ann Jordan, William Gerwick
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Publication number: 20120094303Abstract: A device for determining the presence and/or quantity of one or more analytes in a sample of human body fluid has a container for receiving a sample of body fluid, with an interior that is delimited by a base and by a circumferential surface. It further comprises at least one test strip and a holding element for receiving and holding the one or more test strips. The holding element is designed such that it has a shape corresponding and adapted to the peripheral circumferential surface of the container. The device further comprises an elongate sampling element having an absorbent sampler that takes up the sample of body fluid and by means of which the sample of body fluid is transferred into the container. Further, the base of the container has a central elevation via which the sample of body fluid can be conveyed from the sampler, by compression thereof on the elevation, to the at least one test strip.Type: ApplicationFiled: August 16, 2011Publication date: April 19, 2012Applicant: ulti med Products International GmbHInventors: Matthias W. ENGEL, Leslie Wilson, Paul Johnson
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Publication number: 20110117121Abstract: Methods and compositions for therapy of pain are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of Ganoderma lucidum, an extract of Salvia miltiorrhiza and an extract of Scutellaria barbata and optionally a therapeutically effective amount of an extract of Hippophae rhamnoides are provided. Novel synergistic effects of the use of these compounds in combination therapy are disclosed. Compositions exhibit multiple functions that are useful for the treatment of pain and inflammation. Compositions of the invention inhibit the activity of COX-2 to a greater extent than COX-1. Compositions of the invention also inhibit the nuclear accumulation of NF-kappaB and thus inhibit the expression of a number of proinflammatory molecules including COX-2.Type: ApplicationFiled: October 26, 2007Publication date: May 19, 2011Inventors: James Dao, Jeff Dao, Leslie Wilson, William Gerwick, Emin Oroudjev
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Patent number: 7599839Abstract: A method for speech enabling an application can include the step of specifying a speech input within a speech-enabled markup. The speech-enabled markup can also specify an application operation that is to be executed responsive to the detection of the speech input. After the speech input has been defined within the speech-enabled markup, the application can be instantiated. The specified speech input can then be detected and the application operation can be responsively executed in accordance with the specified speech-enabled markup.Type: GrantFiled: February 11, 2008Date of Patent: October 6, 2009Assignee: Nuance Communications, Inc.Inventors: Charles Cross, Leslie Wilson, Steven Woodward
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Publication number: 20080215331Abstract: A method for speech enabling an application can include the step of specifying a speech input within a speech-enabled markup. The speech-enabled markup can also specify an application operation that is to be executed responsive to the detection of the speech input. After the speech input has been defined within the speech-enabled markup, the application can be instantiated. The specified speech input can then be detected and the application operation can be responsively executed in accordance with the specified speech-enabled markup.Type: ApplicationFiled: February 11, 2008Publication date: September 4, 2008Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Charles Cross, Leslie Wilson, Steven Woodward
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Publication number: 20080008406Abstract: A package comprising: a gusseted tube of film sealed at a top and a bottom thereof by top and bottom cross seals respectively, the bottom seal extending the full width of the package and the top seal extending along a major portion of the package width. The gusseted tube comprises a side gusset extending from the top to the bottom of the tube, wherein the side gusset and the top seal do not overlap. The package further comprises a flexible zipper comprising a first zipper strip joined to a portion of and extending across the width of the side gusset, and a second zipper strip joined to portions of the tube. After the zipper is opened, an upper portion of the side gusset to which the zipper is attached can be inverted to form a pour spout.Type: ApplicationFiled: July 7, 2006Publication date: January 10, 2008Inventors: Glyn Russell, Leslie A. Wilson
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Publication number: 20070227428Abstract: An article has a surface topography for resisting bioadhesion of organisms and includes a base article having a surface. A composition of the surface includes a polymer. The surface has a topography comprising a pattern defined by a plurality of spaced apart features attached to or projected into the base article. The plurality of features each have at least one microscale dimension and at least one neighboring feature having a substantially different geometry. An average feature spacing between adjacent ones of the features is between 10 ?m and 100 ?m in at least a portion of the surface. The surface topography can be numerically represented using at least one sinusoidal function. In one embodiment, the surface can comprise a coating layer disposed on the base article.Type: ApplicationFiled: December 5, 2006Publication date: October 4, 2007Inventors: Anthony Brennan, Ronald Baney, Michelle Carman, Thomas Estes, Adam Feinberg, Leslie Wilson, James Schumacher
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Publication number: 20070178950Abstract: A wearable computing system can comprise a device attachment mechanism and a push to talk actuator. The device attachment mechanism can include a device coupler and a body affixer. The device coupler can detachably couple a portable computing device to the device attachment mechanism. The body affixer can detachably affix the device attachment mechanism to a forearm of a user positioned between a wrist of the user and an elbow of the user. The push to talk actuator can be activated by the user utilizing at least one of an arm, a hand, a wrist, and a finger movement. The push to talk actuator can be coupled to an actuator attachment mechanism that is wearably attached to the user in a hands-free fashion.Type: ApplicationFiled: January 19, 2006Publication date: August 2, 2007Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: James Lewis, Leslie Wilson