Patents by Inventor Lester R. Drewes

Lester R. Drewes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic compounds
    Patent number: 9573888
    Abstract: The invention provides compounds of formula I: or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating cancer or treating autoimmune diseases or preventing transplant rejection using compounds of formula I.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: February 21, 2017
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Venkatram R. Mereddy, Lester R. Drewes, Mohammad Abrar Alam, Sravan K. Jonnalagadda, Shirisha Gurrapu
  • THERAPEUTIC COMPOUNDS
    Publication number: 20160168083
    Abstract: The invention provides compounds of formula I: or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for treating cancer or treating autoimmune diseases or preventing transplant rejection using compounds of formula I.
    Type: Application
    Filed: February 18, 2016
    Publication date: June 16, 2016
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Venkatram R. Mereddy, Lester R. Drewes, Mohammed Abrar Alam, Sravan K. Jonnalagadda, Shirisha Gurrapu
  • Therapeutic compounds
    Patent number: 9296728
    Abstract: The invention provides compounds of formula (I) or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I) and therapeutic methods for treating cancer or treating autoimmune diseases or preventing transplant rejection using compounds of formula (I).
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: March 29, 2016
    Assignee: Regents of the University of Minnesota
    Inventors: Venkatram R. Mereddy, Lester R. Drewes, Mohammed Abrar Alam, Sravan K. Jonnalagadda, Shirisha Gurrapu
  • ISCHEMIA/REPERFUSION PROTECTION COMPOSITIONS AND METHODS OF USING
    Publication number: 20160008325
    Abstract: The invention provides for ischemia/reperfusion protection compositions having one or more ketone bodies and melatonin. The invention also provides for methods of using such compositions to reduce or prevent ischemia/reperfusion injury due to blood loss, stroke or cardiopulmonary arrest or surgery.
    Type: Application
    Filed: September 23, 2015
    Publication date: January 14, 2016
    Inventors: Matthew T. Andrews, Lester R. Drewes, Greg Beilman
  • Ischemia/reperfusion protection compositions and methods of using
    Patent number: 9186340
    Abstract: The invention provides for ischemia/reperfusion protection compositions having one or more ketone bodies and melatonin. The invention also provides for methods of using such compositions to reduce or prevent ischemia/reperfusion injury due to blood loss, stroke or cardiopulmonary arrest or surgery.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: November 17, 2015
    Assignee: Regents of the University of Minnesota
    Inventors: Matthew T. Andrews, Lester R. Drewes, Greg Beilman
  • Ischemia/reperfusion protection compositions and methods of using
    Patent number: 9149450
    Abstract: The invention provides for ischemia/reperfusion protection compositions having one or more ketone bodies and melatonin. The invention also provides for methods of using such compositions to reduce or prevent ischemia/reperfusion injury due to blood loss, stroke or cardiopulmonary arrest or surgery.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: October 6, 2015
    Assignee: Regents of the University of Minnesota
    Inventors: Matthew T. Andrews, Lester R. Drewes, Greg Beilman
  • THERAPEUTIC COMPOUNDS
    Publication number: 20140371272
    Abstract: The invention provides compounds of formula (I) or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I) and therapeutic methods for treating cancer or treating autoimmune diseases or preventing transplant rejection using compounds of formula (I).
    Type: Application
    Filed: January 18, 2013
    Publication date: December 18, 2014
    Inventors: Venkatram R. Mereddy, Lester R. Drewes, Mohammed Abrar Alam, Sravan K. Jonnalagadda, Shirisha Gurrapu
  • ISCHEMIA/REPERFUSION PROTECTION COMPOSITIONS AND METHODS OF USING
    Publication number: 20140235690
    Abstract: The invention provides for ischemia/reperfusion protection compositions having one or more ketone bodies and melatonin. The invention also provides for methods of using such compositions to reduce or prevent ischemia/reperfusion injury due to blood loss, stroke or cardiopulmonary arrest or surgery.
    Type: Application
    Filed: April 24, 2014
    Publication date: August 21, 2014
    Applicant: Regents of the University of Minnesota
    Inventors: Matthew T. Andrews, Lester R. Drewes, Greg Beilman
  • Ischemia/reperfusion protection compositions and methods of using
    Patent number: 8728532
    Abstract: The invention provides for ischemia/reperfusion protection compositions having one or more ketone bodies and melatonin. The invention also provides for methods of using such compositions to reduce or prevent ischemia/reperfusion injury due to blood loss, stroke or cardiopulmonary arrest or surgery.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: May 20, 2014
    Assignee: Regents of the University of Minnesota
    Inventors: Matthew T. Andrews, Lester R. Drewes, Greg Beilman
  • Ischemia/reperfusion protection compositions and methods of using
    Publication number: 20110111049
    Abstract: The invention provides for ischemia/reperfusion protection compositions having one or more ketone bodies and melatonin. The invention also provides for methods of using such compositions to reduce or prevent ischemia/reperfusion injury due to blood loss, stroke or cardiopulmonary arrest or surgery.
    Type: Application
    Filed: April 11, 2008
    Publication date: May 12, 2011
    Inventors: Matthew T Andrews, Lester R. Drewes, Greg Beilman
  • ISCHEMIA/REPERFUSION PROTECTION COMPOSITIONS AND METHODS OF USING
    Publication number: 20100197758
    Abstract: The invention provides for ischemia/reperfusion protection compositions having one or more ketone bodies and melatonin. The invention also provides for methods of using such compositions to reduce or prevent ischemia/reperfusion injury due to blood loss, stroke or cardiopulmonary arrest or surgery.
    Type: Application
    Filed: April 11, 2008
    Publication date: August 5, 2010
    Inventors: Matthew T. Andrews, Lester R. Drewes, Greg Beilman