Patents by Inventor Leszek Lankiewicz

Leszek Lankiewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thionated analogues of thyrotropin releasing hormone
    Patent number: 5244884
    Abstract: There are disclosed thionated analogues of thyrotropin releasing hormone, having the formula: ##STR1## wherein, Q, W, X and Y, same or different, are oxygen or sulfur, with the proviso that at least one of Q, W, X and Y is always sulfur;Z is lower alkyl or (4-imidazolyl)methyl; and the pharmaceutically acceptable salts thereof. The disclosed compounds highly and selectively bind to TRH binding sites in animal tissues, and their utility in treating a variety of diverse physical conditions is disclosed. Pharmaceutical compositions containing the compounds are also disclosed.
    Type: Grant
    Filed: October 19, 1992
    Date of Patent: September 14, 1993
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Arno F. Spatola, Leszek Lankiewicz, Virender M. Labroo, Stefan Vonhof