Patents by Inventor Letizia Longo

Letizia Longo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucose-6-phosphate dehydrogenase deficient mice and methods of using same
    Patent number: 6069297
    Abstract: Mice which produce measurable levels of glucose-6-phosphate dehydrogenase (G6PD) deficient red blood cells can be used as animal models to evaluate new drugs for risk of inducing hemolytic anemia in G6PD-deficient individuals, and for pre-clinical evaluation of gene therapy protocols to correct G6PD deficiency. Deficient and wild-type cells can be distinguished using a tetrazolium dye, and the numbers of each type of cell counted before and after exposure of the cells to the drug or therapy.
    Type: Grant
    Filed: December 5, 1997
    Date of Patent: May 30, 2000
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Lucio Luzzatto, Letizia Longo