Patents by Inventor Leung Sang Nelson Tang

Leung Sang Nelson Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining the copy number of a tandem repeat sequence
    Patent number: 11639521
    Abstract: The present invention provides novel compositions and methods for assessing the size of tandem repeat sequences, e.g., telomeres, within a genome, using specially designed Molecular Inversion Probes (MIPs) and reaction conditions.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: May 2, 2023
    Assignee: The Chinese University of Hong Kong
    Inventors: Leung Sang Nelson Tang, Suk Ling Ma, Jean Woo
  • METHOD TO QUANTIFY TELOMERE LENGTH AND GENOMIC MOTIFS
    Publication number: 20210010069
    Abstract: The present invention provides novel compositions and methods for assessing the size of tandem repeat sequences, e.g., telomeres, within a genome, using specially designed Molecular Inversion Probes (MIPs) and reaction conditions.
    Type: Application
    Filed: June 3, 2020
    Publication date: January 14, 2021
    Inventors: Leung Sang Nelson Tang, Suk Ling Ma, Jean Woo
  • Determination of gene expression levels of a cell type
    Patent number: 9589099
    Abstract: Methods, systems, and compositions can determine gene expression level of a specified cell-type subpopulation by direct analysis of a cell mixture sample composed of multiple subpopulations of various cell-types without the need of prior separation of the component cell-type subpopulations. A target gene and a reference gene can be identified as being informative for a specific cell-type subpopulation when at least 50% of the gene's transcripts in the cell mixture are from the subpopulation. This relative expression level in the cell mixture of the informative target and reference genes can correlate to the relative expression when measured in the isolated subpopulation. Thus, a similar biomarker can be obtained without the difficult step of isolating the cells of the subpopulation.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: March 7, 2017
    Assignee: The Chinese University of Hong Kong
    Inventor: Leung Sang Nelson Tang
  • DETERMINATION OF GENE EXPRESSION LEVELS OF A CELL TYPE
    Publication number: 20130190194
    Abstract: Methods, systems, and compositions can determine gene expression level of a specified cell-type subpopulation by direct analysis of a cell mixture sample composed of multiple subpopulations of various cell-types without the need of prior separation of the component cell-type subpopulations. A target gene and a reference gene can be identified as being informative for a specific cell-type subpopulation when at least 50% of the gene's transcripts in the cell mixture are from the subpopulation. This relative expression level in the cell mixture of the informative target and reference genes can correlate to the relative expression when measured in the isolated subpopulation. Thus, a similar biomarker can be obtained without the difficult step of isolating the cells of the subpopulation.
    Type: Application
    Filed: July 20, 2012
    Publication date: July 25, 2013
    Applicant: The Chinese University of Hong Kong
    Inventor: Leung Sang Nelson Tang