Patents by Inventor Lev Bromberg
Lev Bromberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7604705Abstract: Methods for the separation of targeted components from gun propellant formulations. In particular, the methods separate targeted components in a usable/useful form. Preferred methods are directed to the separation of nitrocellulose, nitroguanidine and/or nitroglycerine from a formulation containing one or more of these components.Type: GrantFiled: May 17, 2004Date of Patent: October 20, 2009Assignee: Foster-Miller, Inc.Inventors: Nese Orbey, B. Michael Cushman, Marina Temchenko, Lev Bromberg
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Publication number: 20080003288Abstract: A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions.Type: ApplicationFiled: April 11, 2007Publication date: January 3, 2008Applicant: Supratek Pharma Inc.Inventors: Lev Bromberg, Marina Temchenko
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Patent number: 7273891Abstract: A graft reverse thermal hydrogel which does not show substantial loss of complex viscosity at and up to 20 degrees above the transition temperature upon autoclaving or aging. Other embodiments include the graft reverse thermal copolymer which can be dissolved in water to produce the graft reverse thermal hydrogel, a process for manufacturing the graft reverse thermal copolymer and hydrogel and applications for the stable graft reverse thermal hydrogel.Type: GrantFiled: January 15, 2003Date of Patent: September 25, 2007Assignee: B L PartnershipInventors: Lev Bromberg, Elmer C. Lupton
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Patent number: 7008628Abstract: A pharmaceutic composition includes a pharmaceutically acceptable carrier, comprising a reverse thermally viscosifying polymer. The polymer includes a linear block copolymer, wherein at least one block comprises a poloxamer; and at least one block comprises a biocompatible polymer or oligomer, in an aqueous medium. The composition also includes an active agent which imparts a pharmaceutic or cosmetic effect. The composition viscosifies in response to an environmental stimulus. The composition is suitable for administration of the pharmaceutical agent across dermal, otic, rectal, vaginal, ophthalmic, esophageal and nasal mucosal membranes.Type: GrantFiled: November 13, 2001Date of Patent: March 7, 2006Assignee: Madasa LLCInventors: Eyal S. Ron, Lev Bromberg, Marina Temchenko
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Publication number: 20060040388Abstract: One aspect of the present invention relates to magnetic nanoparticles colloidally stabilized in aqueous milieu by association with an organic phase. The organic phase may be either a fluorinated polymer or an organic hydrocarbon bilayer, wherein the two layers are chemically bonded to each other. The stabilized particles are further non-toxic and provide useful enhancements in bioprocesses. Another aspect of the present invention relates to compositions comprising an oxygen-dissolving fluid vehicle and surface modified, nanometer-sized magnetic particles. The inventive compositions have utility in a wide range of applications, but are particularly suitable for use as recyclable oxygen carriers, separation and purification vehicles, and bioprocessing media, including fermentation processes.Type: ApplicationFiled: December 20, 2004Publication date: February 23, 2006Inventors: Lev Bromberg, T. Hatton, I. Wang, Jin Yin, Bernat Olle
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Patent number: 7001934Abstract: Inkjet ink systems are disclosed which comprise a) a liquid vehicle, b) a colorant, and c) a gelling agent. The gelling agent may be incorporated either into the liquid vehicle, into a second jettable composition, or onto a substrate. The gelling agent may also be attached to the colorant. In addition, several methods of generating an image are also described which utilize compositions comprising a gelling agent.Type: GrantFiled: January 24, 2002Date of Patent: February 21, 2006Assignee: Cabot CoroporationInventor: Lev Bromberg
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Publication number: 20040131838Abstract: A temperature regulation and flow control device is described. A web of material, e.g., for a wet suit, has a layer of gel particles embedded in a flow control layer, preferably a foam matrix. A water permeable neoprene layer covers the flow control layer and allows water to enter the suit. The flow of water in the suit is regulated by the expansion and contraction of the gel as it undergoes a volume phase transition in response to a change in temperature. When the diver is in cold water, the cold water enters the foam substrate and the gel expands, causing permeability (i.e., flow) to decrease. Flow is restricted in response to cooling, and the foam substrate expands and tightens the fit of the wet suit. In warmer water, an opposite effect occurs, whereby the gel contracts and flow increases. The gel contracts relaxing the fit of the suit. A gel having a particular volume phase transition critical temperature is selected in order to maintain body temperature in a particular environment.Type: ApplicationFiled: December 8, 2003Publication date: July 8, 2004Applicant: Mide Technology CorporationInventors: Marco Serra, Lev Bromberg, Jaco van Reenen Pretorius, Brett P. Masters
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Patent number: 6698510Abstract: A temperature regulation and flow control device is described. A web of material, e.g., for a wet suit, has a layer of gel particles embedded in a flow control layer, preferably a foam matrix. A water permeable neoprene layer covers the flow control layer and allows water to enter the suit. The flow of water in the suit is regulated by the expansion and contraction of the gel as it undergoes a volume phase transition in response to a change in temperature. When the diver is in cold water, the cold water enters the foam substrate and the gel expands, causing permeability (i.e., flow) to decrease. Flow is restricted in response to cooling, and the foam substrate expands and tightens the fit of the wet suit. In warmer water, an opposite effect occurs, whereby the gel contracts and flow increases. The gel contracts relaxing the fit of the suit. A gel having a particular volume phase transition critical temperature is selected in order to maintain body temperature in a particular environment.Type: GrantFiled: April 24, 2001Date of Patent: March 2, 2004Assignee: Mide Technology CorporationInventors: Marco Serra, Lev Bromberg, Jaco van Reenen Pretorius, Brett P. Masters
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Publication number: 20030153649Abstract: Inkjet ink systems are disclosed which comprise a) a liquid vehicle, b) a colorant, and c) a gelling agent. The gelling agent may be incorporated either into the liquid vehicle, into a second jettable composition, or onto a substrate. The gelling agent may also be attached to the colorant. In addition, several methods of generating an image are also described which utilize compositions comprising a gelling agent.Type: ApplicationFiled: January 24, 2002Publication date: August 14, 2003Inventor: Lev Bromberg
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Publication number: 20030092776Abstract: A pharmaceutic composition includes a pharmaceutically acceptable carrier, comprising a reverse thermally viscosifying polymer. The polymer includes a linear block copolymer, wherein at least one block comprises a poloxamer; and at least one block comprises a biocompatible polymer or oligomer, in an aqueous medium. The composition also includes an active agent which imparts a pharmaceutic or cosmetic effect. The composition viscosifies in response to an environmental stimulus. The composition is suitable for administration of the pharmaceutical agent across dermal, otic, rectal, vaginal, ophthalmic, esophageal and nasal mucosal membranes.Type: ApplicationFiled: November 13, 2001Publication date: May 15, 2003Inventors: Eyal S. Ron, Lev Bromberg, Marina Temchenko
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Patent number: 6552555Abstract: An integrated circuit testing apparatus includes a probe card and a probe unit. The probe unit includes a plurality of conductive elastic bumps and a plurality of conductors positioned to conduct signals from the bumps to the probe card. The testing apparatus can further includes a substrate disposed between the probe card and the probe unit, and a flexible member disposed adjacent the substrate.Type: GrantFiled: November 19, 1999Date of Patent: April 22, 2003Assignee: Custom One Design, Inc.Inventors: Peter R. Nuytkens, Lev Bromberg, Patrick G. Dannen, Andrew D. Miller, Ahmed Mitwalli, Robert A. Most
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Publication number: 20030010486Abstract: A temperature regulation and flow control device is described. A web of material, e.g., for a wet suit, has a layer of gel particles embedded in a flow control layer, preferably a foam matrix. A water permeable neoprene layer covers the flow control layer and allows water to enter the suit. The flow of water in the suit is regulated by the expansion and contraction of the gel as it undergoes a volume phase transition in response to a change in temperature. When the diver is in cold water, the cold water enters the foam substrate and the gel expands, causing permeability (i.e., flow) to decrease. Flow is restricted in response to cooling, and the foam substrate expands and tightens the fit of the wet suit. In warmer water, an opposite effect occurs, whereby the gel contracts and flow increases. The gel contracts relaxing the fit of the suit. A gel having a particular volume phase transition critical temperature is selected in order to maintain body temperature in a particular environment.Type: ApplicationFiled: April 24, 2001Publication date: January 16, 2003Applicant: Mide Technology CorporationInventors: Marco Serra, Lev Bromberg, Jaco van Reenen Pretorius, Brett P. Masters
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Patent number: 6316011Abstract: A pharmaceutic composition includes a pharmaceutically acceptable carrier, comprising a reverse thermally viscosifying polymer. The polymer includes a linear block copolymer, wherein at least one block comprises a poloxamer; and at least one block comprises a biocompatible polymer or oligomer, in an aqueous medium. The composition also includes an active agent which imparts a pharmaceutic or cosmetic effect. The composition viscosities in response to an environmental stimulus. The composition is suitable for administration of the pharmaceutical agent across dermal, otic, rectal, vaginal, ophthalmic, esophageal and nasal mucosal membranes.Type: GrantFiled: August 4, 1999Date of Patent: November 13, 2001Assignee: Madash, LLCInventors: Eyal S. Ron, Lev Bromberg, Marina Temchenko
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Patent number: 6153669Abstract: The materials include non-polyampholite crosslinked polymers and gels based on a polymer which in uncrosslinked form is substantially soluble in ionic fluids and substantially insoluble in water. The materials change their state of hydration in response to an environmental trigger. The disclosed materials are useful as drilling, completion or workover fluids in wells such as hydrocarbon producing wells. According to the disclosed method, crosslinked polymers or gels are introduced into a stratum, blocking or bridging the pores of the stratum. Thereafter, an environmental condition is changed to cause the hydrated material to become less hydrated to unblock the pores allowing production from the well.Type: GrantFiled: January 8, 1999Date of Patent: November 28, 2000Assignee: Baroid Drilling Fluids, Inc.Inventors: David Diggs, Marie Kearney, M. J. Timm, E. C. Lupton, Lev Bromberg, Mara Stein, Barry Hand, Michael Orkisz
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Patent number: 6110876Abstract: The materials include non-polyampholite crosslinked polymers and gels based on a polymer which in uncrosslinked form is substantially soluble in ionic fluids and substantially insoluble in water. The materials change their state of hydration in response to an environmental trigger. The disclosed materials are useful as drilling, completion or workover fluids in wells such as hydrocarbon producing wells. According to the disclosed method, crosslinked polymers or gels are introduced into a stratum, blocking or bridging the pores of the stratum. Thereafter, an environmental condition is changed to cause the hydrated material to become less hydrated to unblock the pores allowing production from the well.Type: GrantFiled: January 8, 1999Date of Patent: August 29, 2000Assignee: Baroid Drilling Fluids, Inc.Inventors: David Diggs, Marie Kearney, M. J. Timm, E. C. Lupton, Lev Bromberg, Mara Stein, Barry Hand, Michael Orkisz
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Patent number: 6013698Abstract: Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first nonaqueous reactive material, and encapsulation of the swollen gel with a second nonaqueous reactive material. Gels precursors may be synthesized from crosslinking polymers, or alternatively, may be formed by crosslinking and polymerizing a monomer starting material. An accelerator may be utilized to facilitate swelling of the gel precursor with the first nonaqueous reactive material. Foams and composites may also be swollen with the first nonaqueous reactive material. The swollen gel is then contacted with a second nonaqueous reactive material such that an encapsulation layer is formed thereby. The encapsulated gels may be stored for subsequent use.Type: GrantFiled: October 5, 1998Date of Patent: January 11, 2000Assignee: MedLogic Global CorporationInventors: E. C. Lupton, Xiaohong Yu, Lev Bromberg, Barry Joseph Hand
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Patent number: 5939485Abstract: A responsive polymer network exhibiting the property of reversible gelation in response to a change in an environmental stimulus is provided. The aqueous solution of the network polymer, comprises about 0.01 to 20 wt % by weight of a responsive component and about 0.01 to 20 wt % by weight of a structural component capable of supporting and interacting with the responsive component. The aqueous composition exhibits at least a five-fold increase in viscosity upon gelation. The gelation may be triggered by a change in an environmental stimulus, such as temperature, pH and ionic strength.Type: GrantFiled: January 3, 1996Date of Patent: August 17, 1999Assignee: MedLogic Global CorporationInventors: Lev Bromberg, Elmer Cornelius (E.C.) Lupton, Matthew E. Schiller, Mary Jo (M.J.) Timm, George McKinney
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Patent number: 5932285Abstract: Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first nonaqueous reactive material, and encapsulation of the swollen gel with a second nonaqueous reactive material. Gels precursors may be synthesized from crosslinking polymers, or alternatively, may be formed by crosslinking and polymerizing a monomer starting material. An accelerator may be utilized to facilitate swelling of the gel precursor with the first nonaqueous reactive material. Foams and composites may also be swollen with the first nonaqueous reactive material. The swollen gel is then contacted with a second nonaqueous reactive material such that an encapsulation layer is formed thereby. The encapsulated gels may be stored for subsequent use.Type: GrantFiled: February 17, 1995Date of Patent: August 3, 1999Assignee: MedLogic Global CorporationInventors: E. C. Lupton, Xiaohong Yu, Lev Bromberg, Barry Joseph Hand
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Patent number: 5888943Abstract: The materials include non-polyampholite crosslinked polymers and gels based on a polymer which in uncrosslinked form is substantially soluble in ionic fluids and substantially insoluble in water. The materials change their state of hydration in response to an environmental trigger. The disclosed materials are useful as drilling, completion or workover fluids in wells such as hydrocarbon producing wells. According to the disclosed method, crosslinked polymers or gels are introduced into a stratum, blocking or bridging the pores of the stratum. Thereafter, an environmental condition is changed to cause the hydrated material to become less hydrated to unblock the pores allowing production from the well.Type: GrantFiled: December 11, 1995Date of Patent: March 30, 1999Assignee: Baroid Drilling Fluids, Inc.Inventors: David Diggs, Marie Kearney, M. J. Timm, E. C. Lupton, Lev Bromberg, Mara Stein, Barry Hand, Michael Orkisz
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Patent number: 5849412Abstract: Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first nonaqueous reactive material, and encapsulation of the swollen gel with a second nonaqueous reactive material. Gels precursors may be synthesized from crosslinking polymers, or alternatively, may be formed by crosslinking and polymerizing a monomer starting material. An accelerator may be utilized to facilitate swelling of the gel precursor with the first nonaqueous reactive material. Foams and composites may also be swollen with the first nonaqueous reactive material. The swollen gel is then contacted with a second nonaqueous reactive material such that an encapsulation layer is formed thereby. The encapsulated gels may be stored for subsequent use.Type: GrantFiled: June 7, 1995Date of Patent: December 15, 1998Assignee: MedLogic Global CorporationInventors: Lev Bromberg, Elmer C. Lupton, Jr., Barry Joseph Hand