Patents by Inventor Lev Shaket

Lev Shaket has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for isolating DNA molecules by generating a progenitor collection catalog
    Patent number: 11053493
    Abstract: Systems and methods for isolating DNA molecules that can include the steps of: providing a transposon mutant collection, the transposon mutant collection being stored in a plurality of wells; dispatching aliquots from each well in the transposon mutant collection to a set of pools in a combinatorial pooling array that uses pool address coordinates, the aliquots being dispatched to the set of pools based on a location of the aliquots within the transposon mutant collection; constructing an amplicon library, the amplicon library including a sequencing dataset; parsing the sequencing dataset to a set of putative transposon insertion locations and pool address coordinates; calculating a likelihood for each location and pool address coordinates within the set of putative transposon insertion locations and pool address coordinates using a Bayesian inference algorithm informed by internal self-consistency; and generating a progenitor collection catalog based on location and pool address coordinates verified in the c
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: July 6, 2021
    Inventors: Buz Barstow, Michael Baym, Lev Shaket, Isao Anzai, Oluwakemi Adesina
  • Engineered genetic enteric sensor bacteria and uses thereof
    Patent number: 10907221
    Abstract: The disclosure relates to genetic engineered bacteria having a genetic memory circuit, compositions thereof, formulations thereof, methods of analyses and method of treatment of conditions related to the gastrointestinal tract including the mouth and the stomach.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: February 2, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Jonathan Kotula, Scott Jordan Kerns, Jeffrey Charles Way, Pamela A. Silver, Lev Shaket
  • SYSTEM FOR ISOLATING DNA MOLECULES
    Publication number: 20170321212
    Abstract: Systems and methods for isolating DNA molecules that can include the steps of: providing a transposon mutant collection, the transposon mutant collection being stored in a plurality of wells; dispatching aliquots from each well in the transposon mutant collection to a set of pools in a combinatorial pooling array that uses pool address coordinates, the aliquots being dispatched to the set of pools based on a location of the aliquots within the transposon mutant collection; constructing an amplicon library, the amplicon library including a sequencing dataset; parsing the sequencing dataset to a set of putative transposon insertion locations and pool address coordinates; calculating a likelihood for each location and pool address coordinates within the set of putative transposon insertion locations and pool address coordinates using a Bayesian inference algorithm informed by internal self-consistency; and generating a progenitor collection catalog based on location and pool address coordinates verified in the c
    Type: Application
    Filed: May 5, 2017
    Publication date: November 9, 2017
    Inventors: Buz Barstow, Michael Baym, Lev Shaket, Isao Anzai, Oluwakemi Adesina