Patents by Inventor Levon Khachigian

Levon Khachigian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vascular therapeutics
    Publication number: 20050222065
    Abstract: The present invention provides a method of preventing or reducing restenosis, neointima formation, graft failure, atherosclerosis, angiogenesis and/or solid tumour growth in a subject. The method comprises administering to the subject a prophylactically effective dose of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun. It is preferred that the nucleic acid is a DNAzyme that targets c-Jun mRNA.
    Type: Application
    Filed: September 23, 2004
    Publication date: October 6, 2005
    Inventor: Levon Khachigian
  • Vascular therapeutics
    Publication number: 20050119213
    Abstract: The present invention provides a method of preventing or reducing restenosis, neointima formation, graft failure, atherosclerosis, angiogenesis and/or solid tumour growth in a subject The method comprises administering to the subject a prophylactically effective dose of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun. It is preferred that the nucleic acid is a DNAzyme that targets c-Jun mRNA.
    Type: Application
    Filed: August 20, 2004
    Publication date: June 2, 2005
    Inventor: Levon Khachigian
  • Yin yang-1
    Publication number: 20050054591
    Abstract: The present invention provides a method of preventing or reducing cellular proliferation. The method involves administering to cells a composition which increases the level of YY1 protein, in particular YY1 mRNA, in the cells.
    Type: Application
    Filed: May 21, 2002
    Publication date: March 10, 2005
    Inventor: Levon Khachigian