Patents by Inventor Levon M. Khachigian

Levon M. Khachigian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130237696
    Abstract: The present invention provides a method of preventing or reducing restenosis, neointima formation, graft failure, atherosclerosis, angiogenesis and/or solid tumour growth in a subject. The method comprises administering to the subject a prophylactically effective dose of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun. It is preferred that the nucleic acid is a DNAzymc that targets c-Jun mRNA.
    Type: Application
    Filed: July 12, 2012
    Publication date: September 12, 2013
    Inventor: Levon M. KHACHIGIAN
  • Publication number: 20130237588
    Abstract: The present invention provides a method of preventing or reducing restenosis, neointima formation, graft failure, atherosclerosis, angiogenesis and/or solid tumour growth in a subject. The method comprises administering to the subject a prophylactically effective dose of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun. It is preferred that the nucleic acid is a DNAzyme that targets c-Jun mRNA.
    Type: Application
    Filed: July 12, 2012
    Publication date: September 12, 2013
    Inventor: Levon M. KHACHIGIAN
  • Patent number: 8242090
    Abstract: The present invention provides a method of preventing or reducing restenosis, neointima formation, graft failure, atherosclerosis, angiogenesis and/or solid tumor growth in a subject The method comprises administering to the subject a prophylactically effective dose of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun. It is preferred that the nucleic acid is a DNAzyme that targets c-Jun mRNA.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: August 14, 2012
    Assignee: Newsouth Innovations PTY Limited
    Inventor: Levon M. Khachigian
  • Publication number: 20110065772
    Abstract: The present invention provides a method for treating or inhibiting rheumatoid arthritis in a subject, the method comprising administering to the subject a therapeutically effective amount of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun protein.
    Type: Application
    Filed: June 29, 2007
    Publication date: March 17, 2011
    Inventor: Levon M. Khachigian