Patents by Inventor Lewis Choi

Lewis Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted macrocyclic compounds and related methods of treatment
    Patent number: 12054495
    Abstract: The present invention provides compounds useful for the treatment of narcolepsy or cataplexy in a subject in need thereof. Related pharmaceutical compositions and methods are also provided herein.
    Type: Grant
    Filed: November 22, 2022
    Date of Patent: August 6, 2024
    Assignee: Alkermes, Inc.
    Inventors: Lewis D. Pennington, Younggi Choi, Hoan Huynh, Brian M. Aquila, Ingo Andreas Mugge, Yuan Hu, James R. Woods, Roman A. Valiulin, Brian Kenneth Raymer, Jörg Martin Bentzien, Michael R. Hale, Jonathan Ward Lehmann, Daljit Matharu, Srinivasa Karra
  • Pegylated Ion Channel Modulating Compounds
    Publication number: 20080021005
    Abstract: This invention is directed to PEGlyated derivatives, drug conjugates and isotopic derivatives of certain ion channel modulating compounds.
    Type: Application
    Filed: March 31, 2005
    Publication date: January 24, 2008
    Applicant: Cardiome Pharma Corp.
    Inventors: Elizabeth Cheu, Lewis Choi, Doug Chou, Allen Davidoff, Alan Ezrin, Grace Jung, Bertrand Plouvier, Aregahegn Yifru
  • AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF
    Publication number: 20070254945
    Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
    Type: Application
    Filed: March 23, 2007
    Publication date: November 1, 2007
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Grace Jung, Bertrand Plouvier, Yuzhong Liu, Jeff Zhu, Tao Sheng, Anthony Barrett, Lewis Choi, Doug Chou
  • Aminocyclohexyl ether compounds and uses thereof
    Publication number: 20070099983
    Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
    Type: Application
    Filed: October 31, 2003
    Publication date: May 3, 2007
    Applicant: Cardiome Pharma Corp.
    Inventors: G.M. Barrett, Lewis Choi, Dough Chou, Grace Jung, Bertrand Plouvier, Yuzhong Liu, Jeff Zhu, Tao Sheng
  • Synthetic process for trans-aminocyclohexyl ether compounds
    Publication number: 20060094880
    Abstract: A method of stereoselectively making an aminocyclohexyl ether comprises, for example, reacting to form the aminocyclohexyl ether having the formula respectively, wherein independently at each occurrence, R1 and R2 are independently hydrogen, C1-C8alkyl, C3-C8alkoxyalkyl, C1-C8hydroxyalkyl, or C7-C12aralkyl; or R1 and R2 are independently C3-C8alkoxyalkyl, C1-C8hydroxyalkyl, and C7-C12aralkyl; or R1 and R2, when taken together with the nitrogen atom to which they are directly attached in formula (57) or (75), form a ring denoted by formula (I): wherein the ring of formula (I) is formed from the nitrogen as shown as well as three to nine additional ring atoms independently carbon, nitrogen, oxygen, or sulfur; where any two adjacent ring atoms may be joined together by single or double bonds, and where any one or more of the additional carbon ring atoms may be substituted with one or two substituents selected from the group consisting of hydrogen, hydroxy, C1-C3hydroxyalkyl, oxo, C2-C4acyl, C1-C3
    Type: Application
    Filed: June 4, 2004
    Publication date: May 4, 2006
    Inventors: Anthony Barrett, Lewis Choi
  • Quaternary ammonium compounds and their use as anti-tussive agents
    Publication number: 20050197383
    Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment aid/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula Y-J-EAn? (I), wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).
    Type: Application
    Filed: April 26, 2005
    Publication date: September 8, 2005
    Applicant: UCB Farchim S.A.
    Inventors: Lewis Choi, Gregory Beatch, Clive Page
  • Synthetic process for trans-aminocyclohexyl ether compounds
    Publication number: 20050038256
    Abstract: A method of stereoselectively making an aminocyclohexyl ether comprises, for example, reacting to form the aminocyclohexyl ether having the formula respectively, wherein independently at each occurrence, R1 and R2 are independently hydrogen, C1-C8alkyl, C3-C8alkoxyalkyl, C1-C8hydroxyalkyl, or C7-C12aralkyl; or R1 and R2 are independently C3-C8alkoxyalkyl, C1-C8hydroxyalkyl, and C7-C12aralkyl; or R1 and R2, when taken together with the nitrogen atom to which they are directly attached in formula (57) or (75), form a ring denoted by formula (I): wherein the ring of formula (I) is formed from the nitrogen as shown as well as three to nine additional ring atoms independently carbon, nitrogen, oxygen, or sulfur; where any two adjacent ring atoms may be joined together by single or double bonds, and where any one or more of the additional carbon ring atoms may be substituted with one or two substituents selected from the group consisting of hydrogen, hydroxy, C1-C3hydroxyalkyl, oxo, C2-C4acyl, C1-C3
    Type: Application
    Filed: June 4, 2004
    Publication date: February 17, 2005
    Inventors: Anthony Barrett, Lewis Choi