Abstract: Novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies and have the general formula I: wherein R1, R2, R3, R4, R5 and R6 are as described herein.

Abstract: A method and corresponding system for providing patient data to a patient data server following an offline network condition are described. In one arrangement, a healthcare information analysis and presentation system includes a client logic device disposed in wireless communication with a patient data server. The healthcare information analysis and presentation system is configured with an offline functionality that stores patient data on the client logic device, even when not wirelessly connected to the patient data server. Further, the healthcare information analysis and presentation system is configured to allow the end user to begin patient data entry for a new patient, to document an existing case, and to resolve conflicting data following an offline network condition, all while preserving and protecting patient's privacy.

Abstract: A system and method for obtaining processor diagnostic data. The method can include receiving a instruction, enabling write access of an output stream to a diagnostic memory, writing to the diagnostic memory at a first frequency, and reading from the diagnostic memory at a second frequency where the first frequency is greater than the second frequency.

Abstract: A system and method of controlling input and output in a multi-mode wireless processing system. The method can include receiving an instruction for communication in a multi-mode wireless processing system; and determining from a field in the received instruction whether a designated processing unit generates output data or receives input data.

Abstract: A system and method Fast Fourier Transform (FFT) method in a multi-mode wireless processing system. The method can include loading an input vector into an input buffer, initializing a second counter and a variable N, where N=log2 (input vector size), and s is the value of the second counter, performing an FFT stage, and comparing s to N and performing additional FFT stages until s=N. Performing the FFT stage can include performing vector operations on data in the input buffer and sending results to an output buffer, the data in the input buffer comprising a plurality of segments, advancing the value of the second counter; and switching roles of the input and output buffers. The vector operations can include performing Radix-4 FFT vector operations on the four input data at a time and multiplying the resulting output vectors with a Twiddle factor.

Abstract: A vertical alignment device (10) between a downwardly extending upper spindle (12) on an upper mounting plate (14) of an upper pivot assembly (16) in a head jamb (18) and an upwardly extending lower spindle (20) on a lower mounting plate (22) of a lower pivot assembly (24) on a floor (26) for a glass door structure (28) comprising a body (30). A facility (32) is for attaching in a removable manner an upper portion (34) of the body (30) to the upper spindle (12). A plumb line (36) is provided with a plumb bob (38) affixed to a first end of the plumb line (36). An assembly (40) is for securing a second end of the plumb line (36) to a lower portion (42) of the body (30). The plumb bob (38) will hang down on the plumb line (36) to indicate an aligned location for the lower spindle (20) when the lower mounting plate (22) is bolted up on the floor (26), thereby allowing the glass door structure (28) to operate properly in a swinging manner.

Abstract: A covering for exposed insulation surfaces on fluid conduits for protection from moisture and other environmental factors. The covering typically includes a central fabric layer, such as a woven high density polyethylene fabric surrounded by structures having layers of alternating metal containing foils and puncture resistant polymers. The structures may be bonded to the central fabric layer by a polymer extrusion, such as a low density polyethylene extrusion. An acceptable metal-containing foil may includes aluminum foil, and the puncture resistant polymer may be polyester. The resulting covering may be cut with a hand-held implement, such as scissors or a knife or the like, may be formed into desired shapes manually and will retain the desired shape once formed. The overall thickness of the covering typically is no greater than about 350 microns.

Abstract: A covering for exposed insulation surfaces on fluid conduits for protection from moisture and other environmental factors. The covering typically includes a central fabric layer, such as a woven high density polyethylene fabric surrounded by structures having layers of alternating metal containing foils and puncture resistant polymers. The structures may be bonded to the central fabric layer by a polymer extrusion, such as a low density polyethylene extrusion. An acceptable metal-containing foil may includes aluminum foil, and the puncture resistant polymer may be polyester. The resulting covering may be cut with a hand-held implement, such as scissors or a knife or the like, may be formed into desired shapes manually and will retain the desired shape once formed. The overall thickness of the covering typically is no greater than about 350 microns.

Abstract: A method and material for covering exposed insulation surfaces to protect them from moisture and other environmental factors. The covering typically includes a first, exposed layer of a metal-containing foil, a second layer of a metal-containing foil, a layer of a polymer disposed between the first two layers of foil, a third layer of a metal-containing foil, and a second layer of polymer disposed between the second and third layers of foil. A layer of a pressure sensitive adhesive is applied to one of the exposed layers of foil, and the pressure sensitive adhesive layer is covered with a release liner prior to application. The foil provides the necessary moisture and weather seal while the polymer provides the necessary strength and puncture resistance. The overall thickness of the laminate typically is less than 100 microns, permitting it to be easily cut and manipulated at the job site while providing an effective, long lasting weather seal.

Abstract: A method and material for covering exposed insulation surfaces to protect them from moisture and other environmental factors. The covering typically includes a first, exposed layer of a metal-containing foil, a second layer of a metal-containing foil, a layer of a polymer disposed between the first two layers of foil, a third layer of a metal-containing foil, and a second layer of polymer disposed between the second and third layers of foil. A layer of a pressure sensitive adhesive is applied to one of the exposed layers of foil, and the pressure sensitive adhesive layer is covered with a release liner prior to application. The foil provides the necessary moisture and weather seal while the polymer provides the necessary strength and puncture resistance. The overall thickness of the laminate typically is less than 100 microns, permitting it to be easily cut and manipulated at the job site while providing an effective, long lasting weather seal.

Abstract: Method of inhibiting or treating Human Immunodeficiency Virus (HIV) infection, comprising administering to a patient in need thereof an effective amount of a pharmaceutically acceptable composition comprising a PEG-ASNase compound or asparaginase, and optionally at least one compound selected from the group consisting of protease inhibitor compounds, ribonucleotide reductase inhibitor compounds and HIV reverse transcriptase inhibitor compounds.

Abstract: Method of inhibiting or treating Human Immunodeficiency Virus (HIV) infection, comprising administering to a patient in need thereof an effective amount of a pharmaceutically acceptable composition comprising a PEG-ASNase compound or asparaginase, and optionally at least one compound selected from the group consisting of protease inhibitor compounds, ribonucleotide reductase inhibitor compounds and HIV reverse transcriptase inhibitor compounds.

Abstract: The present invention relates to the field of article manufacture and more particularly to an apparatus for removing the flashing from a manufactured article. The apparatus includes at least one gripping unit for gripping a portion of the flashing. The gripping unit is switched by a pneumatic actuator between an open and a clamping configuration. A support is provided upon which each gripping unit is movably mounted, and an indexing actuator is provided for indexing each gripping unit along the support between a rest position displaced from the support surface and a clamping position adjacent to the support surface. A control unit is provided for controlling the operation of the pneumatic actuator and the indexing actuator to effect removal of the flashing. The control unit causes each gripping unit, when in the clamping position, to switch from the open configuration to the clamping configuration to grip the flashing.

Abstract: A ring mechanism has a cover rail, and a pair of carrier rails nested in side by side relationship between the side edges of the cover rail. Ring elements are mounted on the carrier rails, and the carrier rails can be moved between open and closed over center positions. To lock the carrier rails, a locking member is provided. In one position, it permits free movement of the carrier rails. In a locking position, it engages the carrier rails to prevent them being moved from the closed over center position, thereby preventing opening of the ring elements.

Abstract: A ring mechanism for mounting on a loose leaf binder has ring elements, for retaining paper, secured to carrier rails within a cover rail. The ring elements are moveable between open and closed positions. The ring elements include bottom portions extending to intermediate locations higher than their lower ends, but arranged to support paper below the top of the cover rail. Additionally, the ring elements are mounted so their first ends are spaced above the binder cover. This arrangement provides operating space for the ring elements, while enabling the ring elements to have a large capacity.

Abstract: A laminated, adhesive backing material for application to the rear surface of mirrors to prevent shattering thereof. The backing material of this invention is a three layer laminate which includes a central reinforcing layer sandwiched between two outer layers. The central reinforcing layer typically includes a polyester scrim, while the two outer layers typically are formed of polypropylene. An adhesive layer is provided on the outer surface of one of the outer layers of the laminate. The backing of this invention exceeds a 400 foot/pound test requirement. This backing material is manufactured by heat sealing the central reinforcing layer between the two outer layers and thereafter applying the adhesive to the outer surface of one of the outer layers.

Abstract: A loose-leaf binder has a cover and a ring mechanism. The ring mechanism includes a resilient base plate with curled edges and at least one rib extending laterally and downwardly. The ring mechanism also includes a pair of blades beneath the base plate and between the curled edges, the combined width of the blades being slightly greater than the distance between the curled edges. Also, the blades each have at least one slot along their outside edge to engage the rib. At least one pair of ring members fixed to the blades extend above the base plate to meet in a releasable juncture.

Abstract: A process is described for the electroless deposition of metals on nonmetallic surfaces. After pretreatment of the nonmetallic surface so as to obtain a finish suitable for deposition of sensitizers and activators, the nonmetallic surface is exposed to a sensitizing solution and thereafter in a separate step to an activation solution. The surface is then washed with an aqueous alkaline solution prior to immersion in the electroless plating solution. The separate sensitization and activation steps are particularly suitable where the sensitizing step is also used for pattern generation. The inclusion of the aqueous alkaline wash after the activation step both protects the electroless plating bath from contamination with sensitizer and activator, and also insures a short initition time. Short initiation times are highly desirable especially in the production of electronic circuits because highly uniform metal platings are insured, manufacturing time is considerably reduced and reliability is increased.

Abstract: A process is described for the electroless deposition of metals on nonmetallic surfaces. The process involves pretreatment of the nonmetallic surface so as to obtain a surface finish suitable for deposition of colloidal sensitizers which catalyze electroless metallic deposition. The nonmetallic surface is then exposed to a colloidal catalyst solution (typically SnCl.sub.2 /PdCl.sub.2) followed by an acid rinse. On completion of this surface activation procedure, the surface is exposed to a bath for the electroless deposition of metal. This procedure, which differs from that traditionally used, insures more reliable catalysis for electroless deposition of metals with shorter initiation times and is simpler in procedure and lower in cost.