Patents by Inventor Lewis Ho

Lewis Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190196926
    Abstract: A graphics processing unit (GPU) of a GPU subsystem of a computing device operates in a first rendering mode to process graphics data to produce a first image. The GPU operates in a second rendering mode to process the graphics data to produce a second image. The computing device detects whether a fault has occurred in the GPU subsystem based at least in part on comparing the first image with the second image.
    Type: Application
    Filed: December 21, 2017
    Publication date: June 27, 2019
    Inventors: Alex Kwang Ho Jong, Jay Chunsup Yun, Donghyun Kim, Rahul Gulati, Brendon Lewis Johnson, Andrew Evan Gruber
  • Publication number: 20190197651
    Abstract: A graphics processing unit (GPU) of a GPU subsystem of a computing device processes graphics data to produce a plurality of portions of a first image, and to produce a plurality of portions of a second image. The GPU generates a plurality of data integrity check values associated with the plurality of portions of the first image, and a plurality of data integrity check values associated with the plurality of portions of the second image. The GPU determines whether each of the plurality of portions of the second image matches a corresponding portion of the first image. The GPU determines, prior to producing every portion of the second image, whether an operational fault has occurred in the GPU subsystem based at least in part the determination of whether each of the plurality of portions of the second image matches a corresponding portion of the first image.
    Type: Application
    Filed: December 21, 2017
    Publication date: June 27, 2019
    Inventors: Brendon Lewis Johnson, Andrew Evan Gruber, Jay Chunsup Yun, Rahul Gulati, Donghyun Kim, Alex Kwang Ho Jong
  • Publication number: 20190171538
    Abstract: The disclosure describes techniques for a self-test of a graphics processing unit (GPU) independent of instructions from another processing device. The GPU may perform the self-test in response to a determination that the GPU enters an idle mode. The self-test may be based on information indicating a safety level, where the safety level indicates how many faults in circuits or memory blocks of the GPU need to be detected.
    Type: Application
    Filed: December 5, 2017
    Publication date: June 6, 2019
    Inventors: Rahul Gulati, Andrew Evan Gruber, Brendon Lewis Johnson, Jay Chunsup Yun, Donghyun Kim, Alex Kwang Ho Jong, Anshuman Saxena
  • Publication number: 20190139263
    Abstract: Techniques of this disclosure may include processing data using one or more processors to produce a first image, including storing intermediate first results of processing the data in at least one internal memory of the one or more processors according to a first memory access pattern, processing the data using the one or more processors to produce a second image, including storing intermediate second results of processing the data in the at least one internal memory of the one or more processors according to a second memory access pattern, wherein the second memory access pattern is different than the first memory access pattern, comparing the first image to the second image, and generating an interrupt if the comparison indicates that the first image is different than the second image.
    Type: Application
    Filed: November 6, 2017
    Publication date: May 9, 2019
    Inventors: Andrew Evan Gruber, Rahul Gulati, Brendon Lewis Johnson, Jay Chunsup Yun, Alex Kwang Ho Jong, Donghyun Kim
  • Publication number: 20180371394
    Abstract: Disclosed herein is an improved automatic bioreactor system utilizing a multi-tray or multi-plate cell culture vessel for cultivating adherent cells.
    Type: Application
    Filed: April 17, 2018
    Publication date: December 27, 2018
    Inventors: Timothy Ray Ho, Lewis Ho
  • Publication number: 20180362916
    Abstract: Disclosed herein is an improved automatic sampling and biochemical monitoring system for a microbial or cell culture or a biochemical reaction in a bioreactor.
    Type: Application
    Filed: April 20, 2018
    Publication date: December 20, 2018
    Inventors: Timothy Ray Ho, Lewis Ho
  • Patent number: 9273278
    Abstract: A large scale cell harvesting method for a pack-bed culture device by providing cell growing space that is packed with a plurality of porous matrices and/or matrix means. When a cell detaching step at least comprising shaking or spinning the culture chamber is performed, the unoccupied space is large enough for the porous matrices collide to each other or to the culture chamber to generate momentum whereby the cells detach from the porous matrices to harvest the cells.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: March 1, 2016
    Assignee: CESCO BIOENGINEERING CO., LTD.
    Inventors: Vincent Lee, Peter Chen, Audrey Chen, Alex Liu, Chungnan Fu, Gray Wang, Hugo Chen, King-Ming Chang, Lewis Ho
  • Publication number: 20140193901
    Abstract: A large scale cell harvesting method for a pack-bed culture device by providing cell growing space that is loosely packed with a plurality of porous matrixes and/or matrix means. When a cell detaching step at least comprising shaking or spinning the culture chamber is performed, the unoccupied space is large enough for the porous matrixes collide to each other or to the culture chamber to generate momentum whereby the cells detach from the porous matrixes to harvest the cells.
    Type: Application
    Filed: January 6, 2014
    Publication date: July 10, 2014
    Applicant: CESCO BIOENGINEERING CO., LTD.
    Inventors: Vincent LEE, Peter CHEN, Audrey CHEN, Alex LIU, Chungnan FU, Gray WANG, Hugo CHEN, King-Ming CHANG, Lewis HO
  • Publication number: 20130071872
    Abstract: A single-used matrix sampling device for the single-used, disposable or autoclavble packed-bed bioreactor is provided herein. The present invention includes a tube means and a matrix collecting means. The matrix collecting means configured for collecting the cell culture matrix includes a receptacle and a pulling means connected to the receptacle or the matrix collecting means could be scoop-like in configuration; the tube means is configured for preventing the matrix collecting means from being contaminated while mechanically or pneumatically sampling; and the tube means could be sealed to enclose the sampled matrix collecting means after sampling. A single-used matrix sampling method for a single-used, disposable or autoclavble packed-bed bioreactor is also provided. The present invention could be utilized to aseptically collect the cell culture matrix from the packed-bed bioreactor without requiring to face the risks of contamination.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 21, 2013
    Inventors: Lewis HO, Karen Chen, King-Ming Chang
  • Publication number: 20120250450
    Abstract: An external mixing device comprises: arranging an inlet and an outlet on the single-use container; a sterilizable or a single-use pump head connected to the inlet and outlet with a mixer installed inside. Driven by a driving device, the mixer makes the liquid circulate continuously between the pump head and the single-use container. The external mixing device further comprises a sensor chamber installed with a plurality of sensors and extra ports, which are used for introducing solution or gas inside or for sampling and detecting liquid properties. A single-use connector is used to connect the single-use container to the external mixing device, which can be operated aseptically under general environment. The external mixing device is small-sized with the advantage of simplified operation procedures.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 4, 2012
    Inventors: Lewis Ho, King-Ming Chang
  • Publication number: 20100267142
    Abstract: A scalable packed-bed cell culture device includes a matrix vessel, a mixing vessel, a communicating means, a driving means and a controlling means. The matrix vessel includes porous matrixes packed therein. The mixing vessel includes a mixing means configured for mixing a culture medium. The communicating means is connected between the matrix vessel and the mixing vessel. The driving means is configured for driving the culture medium to flow between the matrix vessel and the mixing vessel. The controlling means configured for controlling the culture medium to submerge the porous matrixes at high level, and to emerge the porous matrixes at low level. An inoculation method and a culture method for scalable packed-bed cell culture device is also herein provided for eliminating the limitation of aeration or oxygenation during culture, alleviating the gradient effect, eliminating the channeling effect in conventional packed-bed bioreactors.
    Type: Application
    Filed: April 16, 2010
    Publication date: October 21, 2010
    Inventors: Gary Wang, King-Ming Chang, Lewis Ho
  • Publication number: 20060292690
    Abstract: The present invention discloses a three-dimensional porous growth surface made from polysaccharide material, especially the alginic acid, to enhance cell growth surface, promote cell adherence, immobilization and propagation, maintain surface structure integrity, enable programmable degradation, and thus increase cellular production. The present invention teaches several methods: a method to enhance the integrity of the growth surface by protecting the growth surface in a rigid solid support; a method of use for enhancing the performance of the surface; and a method of modifying a growth surface for eukaryotic and/or prokaryotic cells comprising the steps of increasing surface area by creating porous and 3-D structure, treating a surface to encourage cell attachment, promoting cell growth and proliferation, and disposing the growth surface in any conventional cell cultivating device. The growth surface is able to program degradation and release the cell/tissue mass after the culture is completed.
    Type: Application
    Filed: June 21, 2006
    Publication date: December 28, 2006
    Inventors: Tzu-Ying Liu, Ing-Kae Wang, Sing-Ying Hsieh, Lewis Ho, Yu-Chi Wang, King-Ming Chang
  • Publication number: 20050186669
    Abstract: An apparatus and method for preparing and culturing cells includes a chamber having an inlet and an outlet for introducing culture medium and air. A cell growth substrate placed in the chamber for cells anchored or embedded. The preferred embodiment of invention claims a novel process for controlling the platform form to tilt at one end, to maintain the seesaw and rocking movement for cultured process. The seesaw movement or rocking movement efficiently the nutrition, carbon dioxide and oxygen transfer during cultured process for production of cellular protein products or harvesting the cells.
    Type: Application
    Filed: February 17, 2005
    Publication date: August 25, 2005
    Inventors: Lewis Ho, Yu-Chi Wang, King-Ming Chang
  • Publication number: 20040086964
    Abstract: The present invention relates to a method for the preparation of a Neutrophil Inhibitory Factor (NIF) comprising the cultivation of mammalian cells expressing NIF in an animal component-free growth medium. The present invention may be employed in large-scale preparation of NIF. The invention also relates to a method for the preparation of recombinant proteins comprising the cultivation of mammalian cells expressing an exogenous recombinant protein in an animal component-free growth medium.
    Type: Application
    Filed: November 7, 2003
    Publication date: May 6, 2004
    Inventors: Stefanie Beate Pluschkell, Roderick William Geldart, Lewis Ho, Mark Alan Koehler, Centenary Afam Okediadi, Stephen Joseph Pias, Marie Meiying Zhu, Steven Joseph Hawrylik, Matthew Moyle
  • Publication number: 20020099183
    Abstract: The present invention relates to a method for the preparation of a Neutrophil Inhibitory Factor (NIF) comprising the cultivation of mammalian cells expressing NIF in an animal component-free growth medium. The present invention may be employed in large-scale preparation of NIF. The invention also relates to a method for the preparation of recombinant proteins comprising the cultivation of mammalian cells expressing an exogenous recombinant protein in an animal component-free growth medium.
    Type: Application
    Filed: February 28, 2001
    Publication date: July 25, 2002
    Inventors: Stefanie Beate Pluschkell, Roderick William Geldart, Lewis Ho, Mark Alan Koehler, Centy Afam Okediadi, Stephen Joseph Pias, Marie Meiying Zhu, Steven Joseph Hawrylik
  • Patent number: 5095179
    Abstract: An extensive morse code processing system includes a microprocessor unit, a transmitter processing unit, a receiver processing unit, a display unit, a keyboard unit, and a radio unit. Whenever a data key on the keyboard is pressed, the ASCII code of the pressed key is received by the microprocessor unit and is converted into a binary line code. The line code is processed by the transmitter unit and is then transmitted as morse code signals by the radio unit. Morse code signals received by the radio unit are converted by the receiver unit into the corresponding binary line code. The line code from the receiver unit serves as input to the microprocessor unit which converts the line code into standard ASCII. The microprocessor then actuates the display unit to display the received characters. Exchange of data between the microprocessor unit and a a computer is also possible through an RS-232 interface adapter interconnecting the computer and the microprocessor unit.
    Type: Grant
    Filed: July 26, 1990
    Date of Patent: March 10, 1992
    Inventor: Lewis Ho