Patents by Inventor Lewis K. Pannell

Lewis K. Pannell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240041438
    Abstract: Embodiments of the present invention relate to non-invasive methods and compositions for collecting detecting, measuring, and identifying target molecules. In some embodiments, methods and compositions relate to target molecules in gastrointestinal lavage fluid or feces.
    Type: Application
    Filed: December 15, 2022
    Publication date: February 8, 2024
    Applicant: Creatics LLC
    Inventors: Lewis K. Pannell, Jana Rocker, Carlo Contreras, Jack Di Palma
  • Publication number: 20220128563
    Abstract: The present invention relates to non-invasive methods for the diagnosis and prognosis of pancreatic cancer. In some embodiments, such methods and compositions relate to particular pancreatic cancer biomarkers and combinations thereof.
    Type: Application
    Filed: July 20, 2021
    Publication date: April 28, 2022
    Applicant: Creatics LLC
    Inventors: Lewis K. Pannell, Jana Rocker
  • Publication number: 20200400673
    Abstract: Described herein are non-invasive or minimally invasive methods and compositions for collecting and assessing samples for detection of gastrointestinal (GI) tract cancers and pancreatic cancers. Samples comprising gastrointestinal lavage fluid (GLF) are obtained from subjects and screened against a glycan microarray to reveal disease-specific glycan-binding patterns by immunoglobulins contained in the GLF, especially immunoglobulin A (IgA). The disease-specific glycan-binding patterns include a disease-specific glycan or subset of glycans from the microarray that are bound by the immunoglobulins in GLF at highest intensities or at lowest intensities, as well as one or more glycan motifs found within this disease-specific subset of glycans.
    Type: Application
    Filed: September 2, 2020
    Publication date: December 24, 2020
    Applicant: Creatics LLC
    Inventors: Lewis K. Pannell, Joseph John Otto
  • Publication number: 20190239863
    Abstract: Embodiments of the present invention relate to non-invasive methods and compositions for collecting detecting, measuring, and identifying target molecules. In some embodiments, methods and compositions relate to target molecules in gastrointestinal lavage fluid or feces.
    Type: Application
    Filed: January 10, 2019
    Publication date: August 8, 2019
    Applicant: Creatics LLC
    Inventors: Lewis K. Pannell, Jana Rocker, Carlo Contreras, Jack Di Palma
  • Publication number: 20190234951
    Abstract: The present invention relates to non-invasive methods for the diagnosis and prognosis of pancreatic cancer. In some embodiments, such methods and compositions relate to particular pancreatic cancer biomarkers and combinations thereof.
    Type: Application
    Filed: July 26, 2018
    Publication date: August 1, 2019
    Applicant: Creatics LLC
    Inventors: Lewis K. Pannell, Jana Rocker
  • Publication number: 20190170769
    Abstract: Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for detecting endometrial cancer or ovarian cancer are provided.
    Type: Application
    Filed: October 12, 2018
    Publication date: June 6, 2019
    Inventors: Michael A. Finan, Rodney P. Rocconi, Lewis K. Pannell
  • Patent number: 10126311
    Abstract: Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for detecting endometrial cancer or ovarian cancer are provided.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: November 13, 2018
    Assignee: UNIVERSITY OF SOUTH ALABAMA
    Inventors: Michael A. Finan, Rodney P. Rocconi, Lewis K. Pannell
  • Publication number: 20160033511
    Abstract: The present invention relates to non-invasive methods for the diagnosis and prognosis of pancreatic cancer. In some embodiments, such methods and compositions relate to particular pancreatic cancer biomarkers and combinations thereof.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 4, 2016
    Inventors: Lewis K. Pannell, Jana Rocker
  • Publication number: 20150241453
    Abstract: Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for detecting endometrial cancer or ovarian cancer are provided.
    Type: Application
    Filed: May 11, 2015
    Publication date: August 27, 2015
    Inventors: Michael A. Finan, Rodney P. Rocconi, Lewis K. Pannell
  • Patent number: 8455624
    Abstract: Some embodiments of the present invention relate to methods and compositions for assessing the absence, presence, progression, or stage of cancer. In particular, methods and compositions for detecting endometrial cancer or ovarian cancer are provided.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: June 4, 2013
    Assignee: University of South Alabama
    Inventors: Michael A. Finan, Rodney P. Rocconi, Lewis K. Pannell
  • Patent number: 6797485
    Abstract: Disclosed herein are methods for identifying at least one bacterial colonization factor of enterotoxigenic E. coil which comprise the following steps in the following order: 1) obtaining the colonization factor; 2) solubilizing the colonization factor by dissolving the colonization factor in 1,1,1,3,3,3-hexafluoro-2-propanol; 3) adding a solution of volatile acid to the solubilized colonization factor of step 2 to obtain a product; 4) subjecting the product of step 3 to mass spectrometry to determine the mass of the colonization factor; and 5) comparing the mass determined in step 4 with the mass of at least one known colonization factor.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: September 28, 2004
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Frederick J. Cassels, Lewis K. Pannell
  • Publication number: 20020106717
    Abstract: Electrospray mass spectrometry has been shown to be useful and extremely accurate (about 1 mass unit/10,000 MW) to a total mass of 30-40 kD. Data clearly shows that use of electrospray mass spectrometry and protein sequencing as applied to the identification of ETEC CF.
    Type: Application
    Filed: August 31, 2001
    Publication date: August 8, 2002
    Inventors: Frederick J. Cassels, Lewis K. Pannell
  • Patent number: 5654432
    Abstract: The present invention provides new antiviral compounds, i.e., michellamines and derivatives and pharmacologically acceptable salts thereof, methods for isolating such antiviral compounds from a plant species of the genus Ancistrocladus, antiviral compositions containing such antiviral compounds, and methods of using such antiviral compounds for treating patients with viral infections. The antiviral compounds of the present invention inhibit the reproduction and cytopathicity of human acquired immunodeficiency viruses.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: August 5, 1997
    Assignee: The United States of America, as represented by the Department of Health and Human Services
    Inventors: Michael R. Boyd, John H. Cardellina, II, Kirk P. Manfredi, John W. Blunt, Lewis K. Pannell, James B. McMahon, Robert J. Gulakowski, Gordon M. Cragg, Gerhard Bringmann, Duncan Thomas, Johnson Jato
  • Patent number: 5455251
    Abstract: The present invention provides new antiviral compounds, i.e., michellamines and derivatives and pharmacologically acceptable salts thereof, methods for isolating such antiviral compounds from a plant species of the genus Ancistrocladus, antiviral compositions containing such antiviral compounds, and methods of using such antiviral compounds for treating patients with viral infections. The antiviral compounds of the present invention inhibit the reproduction and cytopathicity of human acquired immunodeficiency viruses.
    Type: Grant
    Filed: April 19, 1993
    Date of Patent: October 3, 1995
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Michael R. Boyd, John H. Cardellina, II, Kirk P. Manfredi, John W. Blunt, Lewis K. Pannell, James B. McMahon, Robert J. Gulakowski, Gordon M. Cragg, Gerhard Bringmann, Duncan Thomas, Johnson Jato
  • Patent number: 5134969
    Abstract: A cage for arboreal animals includes two compartments, each having a hinged, latched, door. The two compartments are separated by a sliding panel to enable maintenance to be performed easily and safely, minimizing unwanted contact between hazardous animals, such as venomous snakes, for example, and the investigators or maintenance personnel. The structure is further ventilated to provide air flow from bottom to top, and could maintain a humidity level in accordance with needs of caged animals. The sides of the cage are transparent to permit simple monitoring of the reptiles as well as to meet the social needs of those animals which need visual contact with other animals in adjacent cages. This cage meets or exceeds all current Federal principles and regulations for animal housing units.
    Type: Grant
    Filed: October 10, 1990
    Date of Patent: August 4, 1992
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Robert T. Mason, Robert F. Hoyt, Jr., Lewis K. Pannell