Patents by Inventor Lewis S. Choi

Lewis S. Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for protein-liposome coupling
    Patent number: 5399331
    Abstract: This invention relates to a method for synthesizing a substantially pure reactive lipid including, for example, N-[4-(p-maleimidophenyl)-butyryl]phosphatidylethanolamine (MPB-PE) and related compositions. The compositions of the present invention are useful as coupling agents and may be incorporated into liposomes and subsequently coupled to proteins, cofactors and a number of other molecules. A preferred coupling method is also disclosed as are protein conjugates.
    Type: Grant
    Filed: September 17, 1992
    Date of Patent: March 21, 1995
    Assignee: The Liposome Company, Inc.
    Inventors: Helen C. Loughrey, Pieter R. Cullis, Marcel B. Bally, Lewis S. Choi