Patents by Inventor Lewis Siu Leung Choi

Lewis Siu Leung Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic process for aminocyclohexyl ether compounds
    Patent number: 9586899
    Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: March 7, 2017
    Assignee: Cardiome Pharma Corp.
    Inventors: Bertrand M. C. Plouvier, Doug Ta Hung Chou, Grace Jung, Lewis Siu Leung Choi, Tao Sheng, Anthony G. M. Barrett, Marco S. Passafaro, Martin Kurz, Daniel Moeckli, Pirmin Ulmann, Alfred Hedinger
  • SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS
    Publication number: 20150336887
    Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
    Type: Application
    Filed: August 4, 2015
    Publication date: November 26, 2015
    Inventors: Bertrand M.C. Plouvier, Doug Ta Hung Chou, Grace Jung, Lewis Siu Leung Choi, Tao Sheng, Anthony G. M. Barrett, Marco S. Passafaro, Martin Kurz, Daniel Moeckli, Pirmin Ulmann, Alfred Hedinger
  • Synthetic process for aminocyclohexyl ether compounds
    Patent number: 9115081
    Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: August 25, 2015
    Assignee: Cardiome Pharma Corp.
    Inventors: Bertrand M. C. Plouvier, Doug Ta Hung Chou, Grace Jung, Lewis Siu Leung Choi, Tao Sheng, Anthony G. M. Barrett, Marco S. Passafaro, Martin Kurz, Daniel Moeckli, Pirmin Ulmann, Alfred Hedinger
  • Synthetic process for aminocyclohexyl ether compounds
    Patent number: 8692002
    Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
    Type: Grant
    Filed: November 18, 2005
    Date of Patent: April 8, 2014
    Assignee: Cardiome Pharma Corp.
    Inventors: Bertrand M. C. Plouvier, Doug Ta Hung Chou, Grace Jung, Lewis Siu Leung Choi, Tao Sheng, Anthony G. M. Barrett, Marco S. Passafaro, Martin Kurz, Daniel Moeckli, Pirmin Ulmann, Alfred Hedinger
  • SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS
    Publication number: 20130102791
    Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
    Type: Application
    Filed: September 12, 2012
    Publication date: April 25, 2013
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Bertrand M. C. Plouvier, Doug Ta Hung Chou, Grace Jung, Lewis Siu Leung Choi, Tao Sheng, Anthony G. M. Barrett, Marco S. Passafaro, Martin Kurz, Daniel Moeckli, Pirmin Ulmann, Alfred Hedinger
  • Aminocyclohexyl ether compounds and uses thereof
    Patent number: 8163938
    Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: April 24, 2012
    Assignee: Cardiome Pharma Corp.
    Inventors: Grace Jung, Bertrand M. C. Plouvier, Yuzhong Liu, Jeff Jiqun Zhu, Tao Sheng, Anthony G. M. Barrett, Lewis Siu Leung Choi, Doug Ta Hung Chou
  • Prodrugs of ion channel modulating compounds and uses thereof
    Patent number: 7977373
    Abstract: Prodrugs of ion channeling modulating compounds, including, for example, prodrugs of the ion channel modulating compound of the following formula: are described herein, as well as methods of making and using such prodrugs and pharmaceutical compositions containing such prodrugs.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: July 12, 2011
    Assignee: Cardiome Pharma Corp.
    Inventors: Lewis Siu Leung Choi, Doug Ta Hung Chou, Allen W. Davidoff, Adewale Eniade, Bertrand M. C. Plouvier
  • AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF
    Publication number: 20110004006
    Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
    Type: Application
    Filed: July 9, 2010
    Publication date: January 6, 2011
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Grace Jung, Bertrand M. C. Plouvier, Yuzhong Liu, Jeff Jiqun Zhu, Tao Sheng, Anthony G. M. Barrett, Lewis Siu Leung Choi, Doug Ta Hung Chou
  • PEGYLATED ION CHANNEL MODULATING COMPOUNDS
    Publication number: 20100273724
    Abstract: This invention is directed to PEGlyated derivatives, drug conjugates and isotopic derivatives of certain ion channel modulating compounds.
    Type: Application
    Filed: July 7, 2010
    Publication date: October 28, 2010
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Elizabeth L. S. Cheu, Lewis Siu Leung Choi, Doug Ta Hung Chou, Allen W. Davidoff, Alan M. Ezrin, Grace Jung, Bertrand M.C. Plouvier, Aregahegn S. Yifru
  • Drug conjugates of ion channel modulating compounds
    Patent number: 7786119
    Abstract: This invention is directed to drug conjugates of certain ion channel modulating compounds having the following formula: wherein A, X, R1, R2, R3, R4, R5, LB, L and DM are defined herein, including isolated enantiomeric and diastereomeric isomers thereof, and mixtures thereof. Pharmaceutical compositions and methods of use are also disclosed.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: August 31, 2010
    Assignee: Cardiome Pharma Corp.
    Inventors: Elizabeth L. S. Cheu, Lewis Siu Leung Choi, Doug Ta Hung Chou, Allen W. Davidoff, Alan M. Ezrin, Grace Jung, Bertrand M. C. Plouvier, Aregahegn S. Yifru
  • Aminocyclohexyl ether compounds and uses thereof
    Patent number: 7767830
    Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: August 3, 2010
    Assignee: Cardiome Pharma Corp.
    Inventors: Grace Jung, Bertrand M. C. Plouvier, Yuzhong Liu, Jeff Jiqun Zhu, Tao Sheng, Anthony G. M. Barrett, Lewis Siu Leung Choi, Doug Ta Hung Chou
  • SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS
    Publication number: 20100152464
    Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
    Type: Application
    Filed: November 18, 2005
    Publication date: June 17, 2010
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Bertrand M. C. Plouvier, Doug Ta Hung Chou, Grace Jung, Lewis Siu Leung Choi, Tao Sheng, Anthony G. M. Barrett, Marco S. Passafaro, Martin Kurz, Daniel Moeckli, Pirmin Ulmann, Alfred Hedinger
  • PRODRUGS OF ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF
    Publication number: 20090105256
    Abstract: Prodrugs of ion channeling modulating compounds, including, for example, prodrugs of the ion channel modulating compound of the following formula: are described herein, as well as methods of making and using such prodrugs and pharmaceutical compositions containing such prodrugs.
    Type: Application
    Filed: March 31, 2005
    Publication date: April 23, 2009
    Applicant: Cardiome Pharma Corp.
    Inventors: Lewis Siu Leung Choi, Doug Ta Hung Chou, Allen W. Davidoff, Adewale Eniale, Bertrand M.C. Plouvier
  • Quaternary salts of n-substituted cyclic or acyclic amines as pharmaceuticals
    Publication number: 20040214867
    Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of the following formula (I): Y-J-E An− wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).
    Type: Application
    Filed: February 14, 2003
    Publication date: October 28, 2004
    Inventors: Lewis Siu Leung Choi, Gregory N Beatch, Clive Page
  • Quaternary ammonium and their use as anti-tussive agent
    Publication number: 20030181489
    Abstract: In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula Y—J—E An− (I), wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).
    Type: Application
    Filed: February 14, 2003
    Publication date: September 25, 2003
    Inventors: Lewis Siu Leung Choi, Gregory N Beatch, Clive Page
  • Cyclic quaternary ammonium compounds
    Publication number: 20030166629
    Abstract: In one aspect, the present invention concerns the use of certain cyclic quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula (I) wherein n is an integer of from 0 to 4; R1 and E are independently selected from —CH2—R16 and a group represented by formula (II).
    Type: Application
    Filed: February 14, 2003
    Publication date: September 4, 2003
    Inventors: Lewis Siu Leung Choi, Gregory N. Beatch, Clive Page