Abstract: Ultrasound imaging adapts as a function of a coherence factor. Various beamforming, image forming or image processing parameters are varied as a function of a coherence factor to improve detail resolution, contrast resolution, dynamic range or SNR. For example, a beamforming parameter such as the transmit or receive aperture size, apodization type or delay is selected to provide maximum coherence. Alternatively or additionally, an image forming parameter, such as the number of beams for coherent synthesis or incoherent compounding, is set as a function of the coherence factor. Alternatively or additionally an image processing parameter such as the dynamic range, linear or nonlinear video filter and/or linear or nonlinear map may also adapt as a function of the coherence factor.

Abstract: In one embodiment, a medical image viewer in compliance with a medical image standard is provided, and a file in compliance with the medical image standard is provided to the medical image viewer. The medical image standard specifies a first field for data not in compliance with the medical image standard and a second field for data in compliance with the medical image standard. The first field of the file comprises medical image data, and the second field of the file comprises information that can be used to obtain software to at least one of display and manipulate the medical image data. The software is obtained, and at least one of the following is performed with the software: displaying the medical image data and manipulating the medical image data. Other embodiments are provided, and each of the embodiments described herein can be used alone or in combination with one another.

Abstract: The embodiments described herein relate to stepping through the stages of a protocol using an input device and a protocol controller for a medical diagnostic imaging system. The protocol controller may be operative to transition from one stage to a next stage in the protocol in response to no more than a single input from the input device. Thus, a single input from the input device may indicate to the protocol controller to transition to each of the stages of the protocol. In one embodiment, the same single input, such as a stage transition input, is received to transition to each stage of the at least two sequential stages. In another embodiment, different single input, such as different keys on a keyboard, may be used to transition to different stages of the at least two sequential stages. Other embodiments are provided, and each of the embodiments described herein can be used alone or in combination with one another.

Abstract: DNA sequences encoding human platelet-derived growth factor receptors (hPDGF-R), and expression constructs comprising sequences which encode a receptor that can be secreted or incorporated into the membrane of a mammalian cell. Peptide fragments with functions equivalent to the wild-type receptor, conferring a PDGF-sensitive mitogenic response on cells lacking the receptor are provided. The constructs can be used for enhancing PDGF response of cells, determining the regions involved in transducing the signal in response to PDGF binding, providing mutated analogs and evaluating drugs for their physiologic activity. Soluble fragments comprising PDGF receptor sequences are also provided, including important intracellular kinase insert sequences which interact with intracellular proteins.

Abstract: An in-line formed web having major surfaces in the X-Y plane and a depth in the Z direction is suitable for use as a composite fluid distribution and fluid retention layer in a disposable absorbent article. The web contains multiple layers of composite material which may have both thermoplastic fibers and absorbent material. The multiple layers can have different compositions of thermoplastic fibers and absorbent material as applied in-line by various arrangements of thermoplastic melt dies and absorbent fiber dispensers. By arranging at least two of the multiple layers in an opposing relation overlaid in the Z-axis direction of the web, a gradient can be formed in the Z-direction of the web. By coordinating the timing and deposition of the material onto a forming wire, at least one of the multiple layers is arranged to have zones of intermittent material deposition in at least one of a machine direction or a cross direction of the web.

Abstract: DNA sequences encoding human platelet-derived growth factor receptors (hPDGF-R), and expression constructs comprising sequences which encode a receptor that can be secreted or incorporated into the membrane of a mammalian cell. Peptide fragments with functions equivalent to the wild-type receptor, conferring a PDGF-sensitive mitogenic response on cells lacking the receptor are provided. The constructs can be used for enhancing PDGF response of cells, determining the regions involved in transducing the signal in response to PDGF binding, providing mutated analogs and evaluating drugs for their physiologic activity. Soluble fragments comprising PDGF receptor sequences are also provided, including important intracellular kinase insert sequences which interact with intracellular proteins.

Abstract: DNA sequences encoding human platelet-derived growth factor receptors (hPDGF-R), and expression constructs comprising sequences which encode a receptor that can be secreted or incorporated into the membrane of a mammalian cell. Peptide fragments with functions equivalent to the wild-type receptor, conferring a PDGF-sensitive mitogenic response on cells lacking the receptor are provided. The constructs can be used for enhancing PDGF response of cells, determining the regions involved in transducing the signal in response to PDGF binding, providing mutated analogs and evaluating drugs for their physiologic activity. Soluble fragments comprising PDGF receptor sequences are also provided, including important intracellular kinase insert sequences which interact with intracellular proteins.

Abstract: DNA sequences encoding human platelet-derived growth factor receptors (hPDGF-R), and expression constructs comprising sequences which encode a receptor that can be secreted or incorporated into the membrane of a mammalian cell. Peptide fragments with functions equivalent to the wild-type receptor, conferring a PDGF-sensitive mitogenic response on cells lacking the receptor are provided. The constructs can be used for enhancing PDGF response of cells, determining the regions involved in transducing the signal in response to PDGF binding, providing mutated analogs and evaluating drugs for their physiologic activity. Soluble fragments comprising PDGF receptor sequences are also provided, including important intracellular kinase insert sequences which interact with intracellular proteins.

Abstract: Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.

Abstract: This invention provides antibodies that bind to epitopes of human platelet-derived growth factor receptor (hPDGF-R) fragments, wherein the fragments comprise one or more platelet-derived growth factor (PDGF) ligand binding regions from extracellular domains D1, D2, and D3. Also provided are antibodies specific for domain D3, such as monoclonal antibodies directed to the intra-cysteine portion of domain D3.

Abstract: Defined constructs of modified human platelet-derived growth factor receptor polypeptides are provided. Extracellular region domain structures are identified and modifications and combinatorial rearrangements of the receptor segments are provided. Both cell bound and soluble forms of modified segments are made available, as are methods for assays using them, allowing for screening of ligand analogues.

Abstract: New selenium-75 labelled derivatives of cyclic nucleotides are described, which are of value in the saturation analysis of cyclic nucleotides, particularly adenosine-3', 5'-cyclic monophosphate (cyclic AMP) in body fluids.

Abstract: A dynamically tuned gyroscope having a single gimbal has torsion flexures with torsional stiffnesses such that, at its tuned speed, the gyroscope is insensitive to angular vibration at a frequency of twice the rotor rotational speed. The drive shaft is connected to a first torsion flexure having an effective torsional stiffness K.sub.1 of zero, K.sub.1 being made zero by the use of ball races or pivots, by known mechanical methods such as over-center or toggle spring action, or by the use of magnetic or electrostatic systems. The rotor is connected to a second torsion flexure which is orthogonal to the first flexure. The second torsion flexure has a torsional stiffness K.sub.2 equal to 4w.sup.2 r.sub.3.sup.2 m.sub.3 where w is the tuned rotor speed, m.sub.3 is the component mass of a gimbal, on which the torsion flexures are mounted, on an axis through the center of gravity of the gimbal and normal to the plane of the gimbal, and r.sub.3 is the distance of the component mass m.sub.